Lawsonia inermis (Rézéda-péyi) : medicinal properties in alcoholic extraction

Lawsonia inermis (Rézéda-péyi, local réséda, Henna, réséda du pays, Henné) — family Lythracées.

Scientific synonyms : Lawsonia alba-L.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 19 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 191 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Liver disorders associated with diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Sari MI (2018)

     Excerpt The aim of this research was to see the effect of Lawsonia inermis leaves ethanolic extract on liver histopathological of alloxan-induced Wistar rats. Result: The results showed that in P4 group, LLEE dose 600 mg/Kg BW for 28 days able to improve liver tissues structure of alloxan-induced Wistar rats.

   • According to CHIKARADDY A (2012)

     Excerpt Aims: In our study the main objective is to find out the hypoglycemic activity of ethanolic extract of leaves of Lawsonia inermis Linn in alloxan induced diabetic rats & its comparison with the standard drug Glibenclamide. Methodology: Albino rats weighing 200-250gms were selected and diabetes was induced by injecting alloxan monohydrate (180mg/kg b.w) intra peritonially.

   • According to Widyawati T (2019)

     Excerpt inermis leaf extracts on glucose level in normal & streptozotocin-induced diabetic rats. Materials & Methods: Serial extraction of Lawsonia inermis leaf was conducted to obtain the respective n-hexane (HE), ethyl acetate (EAE), ethanol (EE) & distilled water (A1E) extracts.

   • According to Rajwar S (2013)

     Excerpt The Present investigation was undertaken to evaluate the Polyherbal Formulation of Lawsonia inermis & Azadirachta indica in Alloxan & Streptozocin induced diabetic rats. The results showed that the Polyherbal formulation of L inermis & A indica (F1, F2, F3) found to be significant decrease (P<0.01) in blood glucose level as compared to the diabetic control group of animals while F4 & F5 were not significant (P>0.01) compared to the diabetic control group of animals.

   • According to SARI MI (n.d.)

     Excerpt The present study was conducted to evaluate the effect of giving ethanolic extract of Lawsonia inermis leaves to the glucose & Malondialdehyde (MDA) level in alloxan-induced diabetic Wistar male rats. The result showed that LLEE improved blood glucose level (BGLs) of alloxan-induced diabetic rats significantly (p< 0.001) at 29th day.

2. 2

   Type II diabetes mellitus

   Plant part used: Sheet. Mentioned synergistic association: AZADIRACHTA INDICA-A JUSS.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Rajwar S (2013)

     Excerpt The Present investigation was undertaken to evaluate the Polyherbal Formulation of Lawsonia inermis & Azadirachta indica in Alloxan & Streptozocin induced diabetic rats. The results showed that the Polyherbal formulation of L inermis & A indica (F1, F2, F3) found to be significant decrease (P<0.01) in blood glucose level as compared to the diabetic control group of animals while F4 & F5 were not significant (P>0.01) compared to the diabetic control group of animals.

   • According to Widyawati T (2019)

     Excerpt inermis leaf extracts on glucose level in normal & streptozotocin-induced diabetic rats. Materials & Methods: Serial extraction of Lawsonia inermis leaf was conducted to obtain the respective n-hexane (HE), ethyl acetate (EAE), ethanol (EE) & distilled water (A1E) extracts.

   • According to Sari MI (2018)

     Excerpt The aim of this research was to see the effect of Lawsonia inermis leaves ethanolic extract on liver histopathological of alloxan-induced Wistar rats. Methods: Thirty-five of male Wistar rats grouped into five groups, i.e., K (normal) given 0.9% NaCl solution & P1–P4 were induced using alloxan (120 mg/kg BW) intra-peritoneally.

   • According to SARI MI (n.d.)

     Excerpt The present study was conducted to evaluate the effect of giving ethanolic extract of Lawsonia inermis leaves to the glucose & Malondialdehyde (MDA) level in alloxan-induced diabetic Wistar male rats. The result showed that LLEE improved blood glucose level (BGLs) of alloxan-induced diabetic rats significantly (p< 0.001) at 29th day.

   • According to CHIKARADDY A (2012)

     Excerpt Aims: In our study the main objective is to find out the hypoglycemic activity of ethanolic extract of leaves of Lawsonia inermis Linn in alloxan induced diabetic rats & its comparison with the standard drug Glibenclamide. Methodology: Albino rats weighing 200-250gms were selected and diabetes was induced by injecting alloxan monohydrate (180mg/kg b.w) intra peritonially.

3. 3

   Liver disorders: abnormal serum levels: ALT, SGOT, SGPT, bilirubin, albuminuria

   Plant part used: Seed.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Baskaran K (2016)

     Excerpt On 22 day blood was collected through retro orbital puncture and the serum was subjected to liver function tests like, SGOT, SGPT, SALP, bilirubin & total protein. Aim of the study was to evaluate the hepatoprotective activity of ethanolic seed extract of Lawsonia inermis against paracetamol induced liver damage in rats.

   • According to Kumar M (2017)

     Excerpt Treatment of animals with 2-AAF resulted in increased hepatic parameters such as SGOT (2.22-fold), SGPT (1.72-fold), ALP (5.68-fold) & lipid peroxidation (2.94-fold). Different concentration of But-LI demonstrated pronounced protective effects via decreasing levels of SGOT, SGPT, ALP & lipid peroxidation altered by 2-AAF treatment.

   • According to Anand KK (1992)

     Excerpt The hepatoprotective activity of an ethanol-water (1:1) extract of Lawsonia Alba has been studied against CCl4-induced liver toxicity. The effects of the extract on hexobarbitone-induced sleep, BSP clearance, & on certain biochemical parameters indicated its protective role.

   • According to Sari MI (2018)

     Excerpt The aim of this research was to see the effect of Lawsonia inermis leaves ethanolic extract on liver histopathological of alloxan-induced Wistar rats. Observation of the liver histopathological includes changes of the central venous, sinusoid, hepatocyte morphology, & glycogen accumulation, P1–P4 compared to K.

   • According to Rahmat A (2006)

     Excerpt Abstract: The aimed of this study is to extract the essential oil from Strobilanthes crispus(Acanthaceae) & Lawsonia inermis Linn (Lythraceae) & to investigate the chemical constituents, antioxidant activity & cytotoxicity effects of these oils on several cancer cell lines and normal cell lines. The essential oil from L displayed the strongest cytotoxic effect on liver cancer cell lines (HepG2) with50- IC(concentration that inhibit 50% of cell proliferation) value of 24 μg ml.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.