Ocimum gratissimum (Fonbazen) : medicinal properties in alcoholic extraction

Ocimum gratissimum (Fonbazen, Framboisin) — family Lamiacées.

Scientific synonyms : Ocimum guineense-S. & T., O viride-Willd.

Recognised external sources linked to this monograph: TRAMIL.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 21 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 77 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Type II diabetes mellitus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Excerpt According to Ajiboye BA (2024) — excerpt:

   • Excerpt According to this research, the PI3K/AKT pathway of Ocimum gratissimum leaf flavonoid-rich extracts in streptozotocin-induced diabetic rats was studied. Diabetes is a group of medical conditions characterized by the body's inability to effectively control blood glucose levels, due to either insufficient insulin synthesis in type 1 diabetes or inadequate insulin sensitivity in type 2 diabetes.

   • According to ONALOAPO AY (2015)

     Excerpt The present study was undertaken to investigate the effects of ethanolic extracts of Ocimum gratissimum leaves on blood glucose and weight parameters in streptozotocin induced diabetic Wistar rats. Results: Results showed that ethanolic extract of Ocimum gratissimum reduced blood glucose levels and body weight significantly all through the treatment period, that these effects were more rapid with increasing doses of the extract, and the glucose lowering potential of Ocimum gratissimum was comparable to that seen following administration of metformin.

   • According to Ezeorba TPK (2024)

     Excerpt Notably, Ocimum EOs exhibit potent antimicrobial, antioxidant, anti-inflammatory, antidiabetic & anticancer properties, making them promising candidates for alternative medicine & pharmaceutical applications. Ocimum species, including African basil (Ocimum gratissimum) & Holy basil (Ocimum sanctum), are valued for their diverse therapeutic properties particularly in the form of essential oils (EOs).

   • According to Enyevi PB (2020)

     Excerpt Materials & methods: Twenty-four rats weighing 100-160 g were randomly assigned to four treatment groups, the normal & diabetic controls, received a placebo treatment, while groups three and four were administered Glibenclamide & OG leaf-extract (400 mg kg-1 b.wt.), respectively. The aim of the study was to evaluate the effect of OG leaf-extract on hematological indices & lipid profile of Streptozotocin-induced diabetic Wistar rats.

   • According to Aguiyi JC (2000)

     Excerpt The hypoglycaemic effect of the methanolic extract of Ocimum gratissimum leaves was evaluated in normal and alloxan-induced diabetic rats. Intraperitoneal injection of the extract (400 mg/kg) significantly reduced plasma levels both in normal & diabetic rats by 56 & 68%, respectively.

2. 2

   Plant fungi – carrot: Rhizopus stolonifer, Fusarium culmorum, Sclerotinia sclerotiorum, Penicillium expansum

   Plant part used: Pesticidal and veterinary use.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Okoi AI (2013)

     Excerpt The microbial pathogens isolated were Rhizopus stolonifer, Fusarium culmorum, Sclerotinia sclerotiorum and Penicillium expansum. The bioactive and antifungal effects of ethanol extracts of Aframomum meleguetta & Ocimum gratissimum were investigated in vitro on causative agents of post-harvest decay of carrots.

   • According to Lemos J de A (2005)

     Excerpt Ocimum gratissimum, plant known as albahaca (Labiateae family), has been reported earlier with in vitro activity against some bacteria and dermatophytes. gratissimum as a possible antifungal agent.

   • According to Regassa Hunde (2024)

     Excerpt Aloe barbadensis & Ocimum gratissimum are used to cure a variety of sick conditions, both infectious & not.

   • Excerpt According to the results of the antimicrobial experiment, the zones of inhibition created by the disc diffusion method ranged in size from 2±0.26 mm lower to 30±0.34 mm highest for the three extraction techniques, with MTOH extraction producing the highest value of 30±0.34 mm.

   • According to Pandey AK (2014)

     Excerpt Attention is also focused on the biological properties of Ocimum oils which are related to their various interesting applications as antimicrobial, antioxidant, repellent, insecticidal, larvicidal, nematicidal & therapeutic (anti-inflammatory, antinociceptive, antipyretic, antiulcer, analgesic, anthelmintic, anticarcinogenic, skin permeation enhancer, immunomodulatory, cardio-protective, antilipidemic) agents. (O americanum), Ocimum citriodorum, Ocimum gratissimum Linn., Ocimum kilimandscharicum Linn., Ocimum micranthum Willd., Ocimum sanctum Linn., (alt.

   • According to Pandey S (2017)

     Excerpt Ocimum gratissimum has been used in traditional medicine for curing various ailments in tropical countries. This systematic review presents the antiviral, antiprotozoal, antimalarial, insecticides & nematicidal activities of the plant for developing a standard therapeutic system.

3. 3

   Plant fungi – yam: Aspergillus niger, A. flavus, Fusarium oxysporum, Rhizopus stolonifer, Botryodiplodia theobromae, Penicillium chrysogenum

   Plant part used: Pesticidal and veterinary use.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Okigbo RN (2006)

     Excerpt flavus, Fusarium oxysporum Rhizopus stolonifer, Botryodiplodia theobromae & Penicillium chrysogenum. Effects of leaf extracts of Ocimum gratissimum & Aframomum melegueta on spore germination and mycelial reduction of the most occurring fungal pathogen causing soft rot of Yam tuber were investigated.

   • According to Okoi AI (2013)

     Excerpt The microbial pathogens isolated were Rhizopus stolonifer, Fusarium culmorum, Sclerotinia sclerotiorum and Penicillium expansum. The bioactive and antifungal effects of ethanol extracts of Aframomum meleguetta & Ocimum gratissimum were investigated in vitro on causative agents of post-harvest decay of carrots.

   • According to Lemos J de A (2005)

     Excerpt Ocimum gratissimum, plant known as albahaca (Labiateae family), has been reported earlier with in vitro activity against some bacteria and dermatophytes. gratissimum as a possible antifungal agent.

   • According to Regassa Hunde (2024)

     Excerpt Aloe barbadensis & Ocimum gratissimum are used to cure a variety of sick conditions, both infectious & not.

   • Excerpt According to the results of the antimicrobial experiment, the zones of inhibition created by the disc diffusion method ranged in size from 2±0.26 mm lower to 30±0.34 mm highest for the three extraction techniques, with MTOH extraction producing the highest value of 30±0.34 mm.

   • According to Pandey AK (2014)

     Excerpt Attention is also focused on the biological properties of Ocimum oils which are related to their various interesting applications as antimicrobial, antioxidant, repellent, insecticidal, larvicidal, nematicidal & therapeutic (anti-inflammatory, antinociceptive, antipyretic, antiulcer, analgesic, anthelmintic, anticarcinogenic, skin permeation enhancer, immunomodulatory, cardio-protective, antilipidemic) agents. (O americanum), Ocimum citriodorum, Ocimum gratissimum Linn., Ocimum kilimandscharicum Linn., Ocimum micranthum Willd., Ocimum sanctum Linn., (alt.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.