Ocimum gratissimum (Fonbazen) : vertus médicinales en extraction alcoolique

Ocimum gratissimum (Fonbazen, Framboisin) — famille Lamiacées.

Synonymes scientifiques : Ocimum guineense-S. & T., O viride-Willd.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 21 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 77 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Excerpt Selon Ajiboye BA (2024) — extrait :

   • Excerpt According to this research, the PI3K/AKT pathway of Ocimum gratissimum leaf flavonoid-rich extracts in streptozotocin-induced diabetic rats was studied. Diabetes is a group of medical conditions characterized by the body's inability to effectively control blood glucose levels, due to either insufficient insulin synthesis in type 1 diabetes or inadequate insulin sensitivity in type 2 diabetes.

   • Selon ONALOAPO AY (2015)

     Excerpt The present study was undertaken to investigate the effects of ethanolic extracts of Ocimum gratissimum leaves on blood glucose and weight parameters in streptozotocin induced diabetic Wistar rats. Results: Results showed that ethanolic extract of Ocimum gratissimum reduced blood glucose levels and body weight significantly all through the treatment period, that these effects were more rapid with increasing doses of the extract, and the glucose lowering potential of Ocimum gratissimum was comparable to that seen following administration of metformin.

   • Selon Ezeorba TPK (2024)

     Excerpt Notably, Ocimum EOs exhibit potent antimicrobial, antioxidant, anti-inflammatory, antidiabetic & anticancer properties, making them promising candidates for alternative medicine & pharmaceutical applications. Ocimum species, including African basil (Ocimum gratissimum) & Holy basil (Ocimum sanctum), are valued for their diverse therapeutic properties particularly in the form of essential oils (EOs).

   • Selon Enyevi PB (2020)

     Excerpt Materials & methods: Twenty-four rats weighing 100-160 g were randomly assigned to four treatment groups, the normal & diabetic controls, received a placebo treatment, while groups three and four were administered Glibenclamide & OG leaf-extract (400 mg kg-1 b.wt.), respectively. The aim of the study was to evaluate the effect of OG leaf-extract on hematological indices & lipid profile of Streptozotocin-induced diabetic Wistar rats.

   • Selon Aguiyi JC (2000)

     Excerpt The hypoglycaemic effect of the methanolic extract of Ocimum gratissimum leaves was evaluated in normal and alloxan-induced diabetic rats. Intraperitoneal injection of the extract (400 mg/kg) significantly reduced plasma levels both in normal & diabetic rats by 56 & 68%, respectively.

2. 2

   Champignon des végétaux - carotte : Rhizopus stolonifer, Fusarium culmorum, Sclerotinia sclerotiorum, Penicillium expansum

   Partie usitée : Usage parasiticide et veterinaire. Profil pharmacologique documenté : Dowicide-like.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Okoi AI (2013)

     Excerpt The microbial pathogens isolated were Rhizopus stolonifer, Fusarium culmorum, Sclerotinia sclerotiorum and Penicillium expansum. The bioactive and antifungal effects of ethanol extracts of Aframomum meleguetta & Ocimum gratissimum were investigated in vitro on causative agents of post-harvest decay of carrots.

   • Selon Lemos J de A (2005)

     Excerpt Ocimum gratissimum, plant known as albahaca (Labiateae family), has been reported earlier with in vitro activity against some bacteria and dermatophytes. gratissimum as a possible antifungal agent.

   • Selon Regassa Hunde (2024)

     Excerpt Aloe barbadensis & Ocimum gratissimum are used to cure a variety of sick conditions, both infectious & not.

   • Excerpt According to the results of the antimicrobial experiment, the zones of inhibition created by the disc diffusion method ranged in size from 2±0.26 mm lower to 30±0.34 mm highest for the three extraction techniques, with MTOH extraction producing the highest value of 30±0.34 mm.

   • Selon Pandey AK (2014)

     Excerpt Attention is also focused on the biological properties of Ocimum oils which are related to their various interesting applications as antimicrobial, antioxidant, repellent, insecticidal, larvicidal, nematicidal & therapeutic (anti-inflammatory, antinociceptive, antipyretic, antiulcer, analgesic, anthelmintic, anticarcinogenic, skin permeation enhancer, immunomodulatory, cardio-protective, antilipidemic) agents. (O americanum), Ocimum citriodorum, Ocimum gratissimum Linn., Ocimum kilimandscharicum Linn., Ocimum micranthum Willd., Ocimum sanctum Linn., (alt.

   • Selon Pandey S (2017)

     Excerpt Ocimum gratissimum has been used in traditional medicine for curing various ailments in tropical countries. This systematic review presents the antiviral, antiprotozoal, antimalarial, insecticides & nematicidal activities of the plant for developing a standard therapeutic system.

3. 3

   Champignon des végétaux - igname : Aspergillus niger, A. flavus, Fusarium oxysporum Rhizopus stolonifer, Botryodiplodia theobromae, Penicillium chrysogenum

   Partie usitée : Usage parasiticide et veterinaire.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Okigbo RN (2006)

     Excerpt flavus, Fusarium oxysporum Rhizopus stolonifer, Botryodiplodia theobromae & Penicillium chrysogenum. Effects of leaf extracts of Ocimum gratissimum & Aframomum melegueta on spore germination and mycelial reduction of the most occurring fungal pathogen causing soft rot of Yam tuber were investigated.

   • Selon Okoi AI (2013)

     Excerpt The microbial pathogens isolated were Rhizopus stolonifer, Fusarium culmorum, Sclerotinia sclerotiorum and Penicillium expansum. The bioactive and antifungal effects of ethanol extracts of Aframomum meleguetta & Ocimum gratissimum were investigated in vitro on causative agents of post-harvest decay of carrots.

   • Selon Lemos J de A (2005)

     Excerpt Ocimum gratissimum, plant known as albahaca (Labiateae family), has been reported earlier with in vitro activity against some bacteria and dermatophytes. gratissimum as a possible antifungal agent.

   • Selon Regassa Hunde (2024)

     Excerpt Aloe barbadensis & Ocimum gratissimum are used to cure a variety of sick conditions, both infectious & not.

   • Excerpt According to the results of the antimicrobial experiment, the zones of inhibition created by the disc diffusion method ranged in size from 2±0.26 mm lower to 30±0.34 mm highest for the three extraction techniques, with MTOH extraction producing the highest value of 30±0.34 mm.

   • Selon Pandey AK (2014)

     Excerpt Attention is also focused on the biological properties of Ocimum oils which are related to their various interesting applications as antimicrobial, antioxidant, repellent, insecticidal, larvicidal, nematicidal & therapeutic (anti-inflammatory, antinociceptive, antipyretic, antiulcer, analgesic, anthelmintic, anticarcinogenic, skin permeation enhancer, immunomodulatory, cardio-protective, antilipidemic) agents. (O americanum), Ocimum citriodorum, Ocimum gratissimum Linn., Ocimum kilimandscharicum Linn., Ocimum micranthum Willd., Ocimum sanctum Linn., (alt.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.