Pleurotus ostreatus (Oyster mushroom) : medicinal properties in alcoholic extraction

Pleurotus ostreatus (Oyster mushroom, Pleurote) — family Pleurotacées.

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 8 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 45 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment for colorectal, breast and uterine carcinoma

   Plant part used: Mycelium.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Buniel PSA (2018)

     Excerpt Since many of the studies did not show specific varieties of the species used for the evaluation specifically on the anti-tumor and anticancer properties of the species, this study was therefore conducted. Florida had induced DNA damage to HT-29 cancer cell lines & that this variety of the species of PO is a potential source of bioactive compounds important for the treatment of colorectal cancer..

   • According to Nawang L (2018)

     Excerpt The aim of this study was to determined antiproliferative & anti metastatic activity of EEPw (Ethanolic extract of wet Pleorotus ostreatus) & EEPd (Ethanolic extract of dried Pleorotus ostreatus ) in 4T1 metastatic breast cancer cells line. Ethanolic extract of Pleorotus ostreatus (EEP) which contains lovastatin is predicted to inhibit metastatic cancer through inhibition of MMP-2 and MMP-9.

   • According to Cao XY (2015)

     Excerpt The present study aimed to determine the antitumor effects of polysaccharides extracted from Pleurotus ostreatus mycelium on gastric cancer in vitro & in vivo. Polysaccharides were extracted from PO mycelium & an antitumor component, known as PO mycelium polysaccharides 2 (POMP2), with a relative molecular weight of 29 kDa, was then sequentially purified using Sephadex G200 size-exclusion chromatography & diethylaminoethyl-52 cellulose ion-exchange chromatography.

   • According to Mishra V (2021)

     Excerpt Various studies have shown that extracts derived from oyster mushroom is rich in polysaccharides like β-glucan & other macro molecules which have an anti-proliferative effect against cancer cell lines, without harming the normal cells. It also explores the immunomodulatory effects of polysaccharides, proteoglycans & polypeptides derived from oyster mushroom that boosts the immune system to overcome the limitation of traditional cancer therapies.

   • According to Ekowati N (2017)

     Excerpt This study was aimed at obtaining P.ostreatus extract bioactive compounds potential in inhibiting the proliferation of cervical cancer cells (HeLa) & evaluating the HeLa cell proliferation kinetics & HeLa cell death mechanisms. Pleurotus ostreatus is a common mushroom cultivated in Indonesia, & potential properties of bioactive compounds for medicinal mushroom.

2. 2

   Fungal infection: Candida albicans, Candida sp.

   Plant part used: Mycelium.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Vamanu E (2011)

     Excerpt The aim of this work was focused on the obtaining of Pleurotus ostreatus mycelium (Pleurotus ostreatus M2191 & PQMZ91109) by submerged fermentation, in order to get freeze-dried biomass & extracts with high antioxidant & antimicrobial activities. The two Pleurotus species proved narrow antibacterial activity against Gram-negative & Gram-positive bacteria & two Candida strains tested.

   • According to Loganathan RJ (2008)

     Excerpt Loganathan RJ et al, Studies on the phytochemical, antioxidant & antimicrobial properties of three indigenous Pleurotus species.

   • According to Author (2012)

     Excerpt The antioxidant & antimicrobial potential of the ethanolic extract of Pleurotus ostreatus PQMZ91109 mycelium was determined based on inorganic and organic nitrogen sources in the culture medium. The extracts selectively inhibited the tested strains, mainly the two of the genus Candida, at an MIC value of 1.25 mg/mL.

   • According to Vamanu E (2011)

     Excerpt The purpose of the study was to determine the antioxidant activity of ethanolic extracts from the freeze-dried mycelium of the Pleurotus ostreatus M2191 strain, obtained in the presence of corn, malt, yeast extracts and peptone. For the four types of mycelium extracts, the antimicrobial activity was also determined.

   • According to Iwalokun BA (2007)

     Excerpt Iwalokun BA et al, Comparative phytochemical evaluation, antimicrobial & antioxidant properties of Pleurotus ostreatus.

3. 3

   Bacterial infection: Escherichia coli, Bacillus cereus, Listeria innocua, Staphylococcus aureus, Pseudomonas aeruginosa

   Plant part used: Mycelium.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Vamanu E (2011)

     Excerpt The aim of this work was focused on the obtaining of Pleurotus ostreatus mycelium (Pleurotus ostreatus M2191 & PQMZ91109) by submerged fermentation, in order to get freeze-dried biomass & extracts with high antioxidant & antimicrobial activities. The two Pleurotus species proved narrow antibacterial activity against Gram-negative & Gram-positive bacteria & two Candida strains tested.

   • According to Loganathan RJ (2008)

     Excerpt Loganathan RJ et al, Studies on the phytochemical, antioxidant & antimicrobial properties of three indigenous Pleurotus species.

   • According to Vamanu E (2011)

     Excerpt The extract obtained in the presence of peptone selectively inhibited the growth of Gram positive & negative bacteria, Staphylococcus aureus ATCC 6588, Pseudomonas aeruginosa ATCC 15442 being the most susceptible one. The purpose of the study was to determine the antioxidant activity of ethanolic extracts from the freeze-dried mycelium of the Pleurotus ostreatus M2191 strain, obtained in the presence of corn, malt, yeast extracts and peptone.

   • According to Author (2012)

     Excerpt The antioxidant & antimicrobial potential of the ethanolic extract of Pleurotus ostreatus PQMZ91109 mycelium was determined based on inorganic and organic nitrogen sources in the culture medium.

   • According to Iwalokun BA (2007)

     Excerpt Iwalokun BA et al, Comparative phytochemical evaluation, antimicrobial & antioxidant properties of Pleurotus ostreatus.

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.