Saccharum officinarum (Kann) : medicinal properties in alcoholic extraction

Saccharum officinarum (Kann, Kan-dous, Sweet cane, Sugar cane, Canne douce, Canne-à-sucre) — family Poacées.

Scientific synonyms : Saccharum berberi-Jesw, saccharum sinense-Roxb..

This database documents alcoholic (ethanol) extractions of active substances. Our monograph currently lists 10 indications in alcoholic extraction for this species. The Lapo v2 catalogue records 85 scientific references for this species (full detail in the application).

Important — scientific references on this public page: only a short excerpt of each cited source is shown (selected abstract sentences), kept in the original language of the publication (most often English), without translation. These excerpts are not the full article text and are not a complete bibliography. The full reference records and complete monographic detail are available in the Lapo v2 application (free 30-day trial).

1. 1

   Cancer: adjuvant treatment of colorectal, liver and breast cancer

   Plant part used: Bagasse.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Khan SW (2015)

     Excerpt The study was designed to investigate the effects of Saccharum officinarum juice on oxidative liver injury due to INH in mice. The histo-pathological examination of groups A showed normal liver structure which was deranged in (INH) group B, whereas group C showed significant recovery in histological structure.

   • According to Wang L (2018)

     Excerpt Wang L et al, Anti-fibrotic activity of polyphenol-enriched sugarcane extract in rats via inhibition of p38 and JNK phosphorylation, Food & Function, 2 2018-Abstract; Sugarcane (Saccharum officinarum L.), which is one of the most important sources of sugar, is also rich in polyphenolic compounds. Liver fibrosis is the excessive accumulation of extracellular matrix proteins & advanced liver fibrosis, resulting in cirrhosis, liver failure and portal hypertension.

   • According to Kadam US (2008)

     Excerpt Sugarcane (Saccharum officinarum L.) juice is widely consumed by people of the tropics & subtropics. It has been used to cure jaundice & liver-related disorders in Indian systems of medicine.

   • According to Alvarez-Henao MA (2022)

     Excerpt Sugarcane bagasse, is one of the largest agriculture residues in the world & its chemical composition is interesting for several areas. Phytosterols were extracted with supercritical CO2 from sugarcane bagasse.

   • According to Pallavi R (2012)

     Excerpt sugarcane peel (Saccharum Officinarum) was studied for their total phenol content, total flavanoid content, total anthocyanin content, antioxidant & antiproliferative activities. The data represented in this study demonstrated that the amount of phenolic compound and anthocyanin content of sugarcane peel, & determined the antiproliferative activity of sugarcane peel by cytotoxicity assay which shows 51.2% inhibition HT29 cell line at concentration of 0.625µg/ml.

2. 2

   Bacterial infection: Pseudomonas putrida, P. mirabilis, P. aeruginosa, Bacillus subtilis, Staphylococcus wernarii, Staphylococcus aureus

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Palaksha MN (2016)

     Excerpt The different concentrations of chloroform & ethanol extracts (50mg/ml & 100mg/ml) against different Gram negative (Pseudomonas putida ATCC700007 Pseudomonas mirabilis ATCC14153, Pseudomonas aeruginosa ATCC10662) & Gram positive (Bacillus subtilis ATCC11774, Staphylococcus wernari ATCC 27836, Staphylococcus aureus ATCCBAA1026) organisms using well diffusion method, was observed & the results were compared with standard Gentamycin, all the extracts were found to possess significant antibacterial activity. The present work highlights the antibacterial & Anthelmintic activities of Saccharum officinarum leaf extracts.

   • According to Zhao Y (2015)

     Excerpt The sugarcane bagasse extract showed bacteriostatic activity against the growth of Staphylococcus aureus, Listeria monocytogenes, Escherichia coli & Salmonella typhimurium. Results of sodium dodecyl sulfate polyacrylamide gel electrophoresis suggested the antibacterial mechanism was probably due to the damaged cellular proteins by sugarcane bagasse extract.

   • According to Uchenna EF (2015)

     Excerpt Phytochemical analysis & antimicrobial activities of the aqueous ethanolic extract of Saccharum officinarum were carried out. The findings show that the plant bark extract has bactericidal activity & could be used in the control & treatment of bacterial infection especially the gram-negative bacteria.

   • According to Jayakumari V (2007)

     Excerpt Plant extracts and antifungal microorganisms were tested singly & in combination for bio control of sugarcane red rot disease (Colletotrichum falcatum) using two sugarcane (Saccharum officinarum L.) cultivars, CoC671 & CoC92061, in pot & field experiments. Although sugarcane- planting materials (setts) treated individually with either Pseudomonas fluorescens Md1 or A.

3. 3

   Rheumatism, arthritis, osteoarthritis

   Plant part used: Sheet.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • According to Ledon N (2007)

     Excerpt A mixture of fatty acids obtained from sugar cane (Saccharum officinarum L.) wax oil (FAM), in which the main constituents are palmitic, oleic, linoleic, & linolenic acids, was evaluated in two models of inflammation: zymosan-induced arthritis & in the tail test for psoriasis, both on mice. To our knowledge, this is the first report on the anti-inflammatory effect of sugar cane by-products in experimental models of arthritis & psoriasis.

   • According to ASHADE, O.O (2014)

     Excerpt Sugar cane extract is a natural product which has played a wide range biological effects including thrombosis & anti-inflammatory activities. The study suggested that Saccharum officinarum peel ethanolic extract causes mild decline.

   • According to Ghiware N.B (2012)

     Excerpt Results reveals methanolic & ethanolic extracts of S officinarum leaves on animal model have potent anti-inflammatory activity with promising in vitro antioxidant effects. In-vivo anti-inflammatory study by carrageenan induced paw edema reveals that EtSO (87.23%) and MeSO (80.85%) has significant anti-inflammatory activity at 500mg/kg dose at 240 min., in comparison with control and is also comparable to standard Diclofenac.

   • According to Abubakar R (2014)

     Excerpt Abubakar R et al, Impact of Sugar cane peel (Saccharum officinarum) Extract on the Blood Status & Gonadal Integrity of Wistar Albino Rat, Semantic Scholars, 2014-Astract: Sugar cane extract is a natural product which has played a wide range biological effects including thrombosis & anti-inflammatory activities. The study was carried out to evaluate the effects of ethanolic extract of Saccharum officinarum peel on haematological & histopathological parameters.

   • According to Rahlman F (2010)

     Excerpt The addition of molasses (800 microg/mL) to unstimulated whole blood cultures resulted in increased levels of the biomarker of inflammation, Interleukin-6 (P < 0.001) & also the biomarker of humoral immunity, Interleukin-10 (P < 0.001).

Further indications (including other extraction modes where applicable), dosages, precautions for use, and the <strong>full scientific references</strong> (complete records, not only the short excerpts above) are available in the complete monographic record in the Lapo v2 application.