Artocarpus altilis (Fouyapen) : propiedades medicinales en extracción alcohólica

Artocarpus altilis (Fouyapen, Pan de África, Fruit-à-pain, Breadfruit) — familia Moracées.

Sinónimos científicos : Artocarpus communis-TR & G.F, A. incisa-(T)-L. f, var. N.s. Duss, Sitodium Altile Parkinson.

Fuentes externas reconocidas asociadas a esta monografía: TRAMIL.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 16 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 34 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Cáncer: tratamiento adyuvante del carcinoma colorrectal, de mama, de pulmón, de hígado, de útero, de vejiga, de cerebro, de estómago, de riñón, de próstata y de páncreas

   Parte usada: fruta.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hsu (2010)

     Extrait Cytotoxic effects of geranyl flavonoid derivatives from the fruit of Artocarpus communis in SK-Hep-1 human hepatocellular Carcinoma, Food Chem.

   • Selon Juliastuti H (2017)

     Extrait Breadfruit leaf (Artocarpus altilis) can be used to cure several diseases such as renal disease, high blood pressure, liver, diabetes, asthma, toothache, skin infection and cancer in Indonesian community. This study was aimed to examine the hepatoprotective effect of ethanol extract of Indonesian breadfruit leaf in carbon tetrachloride-induced liver injury Wistar rats by measuring Serum Glutamic Pyruvic Transaminase (SGPT) & Malondialdehyde (MDA) levels.

   • Selon WAHYUDIN M (2017)

     Extrait Artocarpus altilis plants have traditionally been used by the people of Indonesia for the treatment of diabetes mellitus. altilis leaf extract that can improve insulin resistance in obese rats (Rattus norvegicus) through identification of the concentrations that can decrease the levels of FFA.

   • Selon Arung TE (2009)

     Extrait Anticancer Properties of Diethyether Extract of Wood from Sukun (Artocarpus altilis) in Human Breast Cancer (T47D) Cells, Trop J of Pharmaceut Res, 2009, 8(4) 317-24.

   • Selon Palupi (2020)

     Extrait This study aimed to evaluate the anti-inflammatory, antioxidant, & immunomodulatory of ethanolic extract of the leaf, fruit, & bark from Artocarpus altilis which is traditionally used for the treatment of inflammation-related diseases. Ethanolic extract of these compounds at 100 & 200 mg/kg doses was orally administered in chronic inflammatory rats induced by Freund's Complete Adjuvant for 14 days to investigate there in vivo anti-inflammatory & antioxidant activity.

2. 2

   Diabetes mellitus tipo I y II

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Puspa DN (2014)

     Extrait Enzyme α-glucosidase inhibition assay of Artocarpus altilis leaf extract shown that ethanol extract, ethyl acetate fraction & two flavonoid compounds (AC-31 & AC-51) have antidiabetic activity stronger than quercetin as positive control with IC50 value 6.79 μg/mL, 5.98 μg/mL, 15.73 μM, & 24.41 μM, respectively.

   • Selon METHI Indravati (s.d.)

     Extrait altilis leaves decoction and GABA on blood glucose levels and insulin expression of bêta-cells in streptozotocin-induced diabetic rats. Information about the Artocarpus altilis leaf as an antidiabetic associated with the active compounds Gamma Amino Butyric Acid (GABA) is still limited.

   • Selon WAHYUDIN M (2017)

     Extrait Artocarpus altilis plants have traditionally been used by the people of Indonesia for the treatment of diabetes mellitus. altilis leaf extract that can improve insulin resistance in obese rats (Rattus norvegicus) through identification of the concentrations that can decrease the levels of FFA.

   • Selon Vienna S (2015)

     Extrait Altilis, one of its major bioactive constituents, has a broad range of pharmacological activity such as antioxidant, antibacterial, anti-inflammatory, antidiabetic & many others. Artocarpus altilis is one kind of herbal medicine that is usually used by Indonesian people.

   • Selon Juliastuti H (2017)

     Extrait Breadfruit leaf (Artocarpus altilis) can be used to cure several diseases such as renal disease, high blood pressure, liver, diabetes, asthma, toothache, skin infection and cancer in Indonesian community.

3. 3

   Hepatitis, normalización de los parámetros hepáticos (MDA y SGPT)

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Juliastuti H (2017)

     Extrait Breadfruit leaf (Artocarpus altilis) can be used to cure several diseases such as renal disease, high blood pressure, liver, diabetes, asthma, toothache, skin infection and cancer in Indonesian community. This study was aimed to examine the hepatoprotective effect of ethanol extract of Indonesian breadfruit leaf in carbon tetrachloride-induced liver injury Wistar rats by measuring Serum Glutamic Pyruvic Transaminase (SGPT) & Malondialdehyde (MDA) levels.

   • Selon Hsu (2010)

     Extrait Cytotoxic effects of geranyl flavonoid derivatives from the fruit of Artocarpus communis in SK-Hep-1 human hepatocellular Carcinoma, Food Chem.

   • Selon WAHYUDIN M (2017)

     Extrait Artocarpus altilis plants have traditionally been used by the people of Indonesia for the treatment of diabetes mellitus. altilis leaf extract that can improve insulin resistance in obese rats (Rattus norvegicus) through identification of the concentrations that can decrease the levels of FFA.

   • Selon Palupi (2020)

     Extrait This study aimed to evaluate the anti-inflammatory, antioxidant, & immunomodulatory of ethanolic extract of the leaf, fruit, & bark from Artocarpus altilis which is traditionally used for the treatment of inflammation-related diseases. The maximum percentage of inflammation, serum levels of peroxide radicals, & liver superoxide dismutase activity were observed, and in vitro antioxidant was measured by using the scavenging of nitric oxide & 2, 2-Diphenyl-1- picrylhydrazyl radicals’ methods.

   • Selon Kingsley AI (2014)

     Extrait Artocarpus altilis is used in ethnomedicine for the treatment of boils & wounds, hypertension, skin infections & in pain management. This study therefore evaluated the anti-inflammatory activity, as well as the antioxidant potential of an ethanol stem bark extract of A altilis.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.