Citrus medica (Mano de Buda) : propiedades medicinales en extracción alcohólica

Citrus medica (Mano de Buda, Main de Bouddha, Buddha's Hand) — familia Rutacées.

Sinónimos científicos : Citrus fragrans Salisb, C Medica var sarcodactylis- (Hoola Van Nooten) -Swingle, C sarcodactylis-VH.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 13 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 137 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Diabetes mellitus tipo II

   Parte usada: fruta.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Peng CH (2009)

     Extrait In conclusion, FC fruits that concomitantly possess insulin secretagogue & slimming effects would be very beneficial to type 2 diabetes mellitus patient. By kinetic analysis on the hypoglycemic patterns of the intraperitoneal glucose tolerance (IPGTT) & the insulin-glucose tolerance tests (IGTT), its insulin secretagogue effect was confirmed.

   • Selon Hetta M (2013)

     Extrait From 70% aqueous methanol extract of the defatted powdered leaves of Citrus medica L. The antihyperglycemic activity exerted a significant reduction in blood glucose level to (105.2±8.35) in diabetic rats after one month of treatment with a dose of 200 mg/kg & to (87.4±6.30) with 400mg, when compared to Gliclazide standard (110.8±7.24) (P< 0.05).

   • Selon Menichini F (2016)

     Extrait This study aimed to investigate the antidiabetic, antilipidaemic & antioxidant activities of Citrus medica cv Diamante (Rutaceae) hydroalcoholic (CD) peel extract in Zucker diabetic fatty (ZDF) rats.

   • Selon Menichini F (2011)

     Extrait This study evaluated the in vitro inhibition of carbohydrate-hydrolysing enzymes, the stimulation of insulin secretion, and the in vivo metabolic effects in mice of Citrus medica L. Measurements of the effects of peel extract on the mouse insulinoma MIN6 β-cells indicated that it did exert direct stimulatory effects on the exocytotic release of insulin in a concentration-dependent manner.

   • Selon Sah AN (2011)

     Extrait The objective of the present investigation was to evaluate the antidiabetic & hypolipidemic activity of petroleum ether extract of Citrus medica Linn. One group was selected as control group (buffer alone) and four groups of STZ induced diabetic rats (n = 5 in each group) were administered vehicle (1% tween 80), seed extract (200 & 400 mg/kg, p.o.) of CM & standard drug Glibenclamide (5 mg/ kg) for 15 days after 10 days of single dose of STZ (60 mg/kg) intraperitoneal administration.

2. 2

   Cáncer: tratamiento adyuvante del adenocarcinoma gástrico

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Suchitra MR (2020)

     Extrait the leaves of Citrus medica have been named traditionally do possess activities in the gastric mucosa. The ethanolic leaf extract of CM possessed antioxidant & anticancer properties in gastric mucosal lines.

   • Selon Alaqeel NK (2023)

     Extrait To explore the most effective uses of citrus peel-derived antioxidants, this review presents background information, an overview of the role of citrus antioxidants in cancer therapy, & a discussion of the key underlying molecular mechanisms. In particular, the antioxidant chemicals found in citrus peel have been identified as potential cancer-fighting agents.

   • Selon Barreca D (2020)

     Extrait The unique characteristics of their basic skeleton & the nature & position of the substituents have attracted & stimulated vigorous investigations as a consequence of an enormous biological potential, that manifests itself as (among other properties) antioxidant, anti-inflammatory, antiviral, antimicrobial, & anticancer activities. Apigenin, diosmetin, luteolin, acacetin, chrysoeriol, and their respective glycosides, that occur in concentrations up to 60 mg/L, are the most common flavones found in Citrus fruits & juices.

   • Selon Liu B (2023)

     Extrait In this study, we synthesized AuNPs using leaf extract of Citrus medica (C. Additionally, it was seen that biosynthesized AuNPs show selective inhibition on the proliferation of HepG2 (human liver cancer cell line) relative to THLE3 (normal adult liver epithelial cells) via generation of ROS & MDA, reduction of GSH level and SOD activity, & over expression of Bax/Bcl-2and Caspase-3 mRNA.

   • Selon Tundis R (2023)

     Extrait This review focused on the composition & biological properties of the EOs of C medica & C Clementina & their main constituents, limonene, γ-terpinene, myrcene, linalool, & sabinene. Citrus is an important genus in the Rutaceae family, with high medicinal & economic value, & includes important crops such as lemons, orange, grapefruits, limes, etc.

3. 3

   Infección bacteriana: S. aureus, L. monocytogenes, E. coli, P. aeruginosa, P. carotovorum

   Parte usada: fruta.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Fratianni F (2019)

     Excerpt Salò̀—cultivated in the Cosenza province, Southern Italy, & to evaluate their antioxidant & antibacterial activity, performed against Escherichia coli, Listeria monocytogenes, Pseudomonas aeruginosa, Staphylococcus aureus, & Pectobacterium carotovorum. The aim of this paper was to study the polyphenols of peel and pulp of three Citrus taxa—Citrus medica, Citrus bergamia, & Citrus medica cv.

   • Selon Vitalini S (2022)

     Excerpt The antibacterial activity against Bacillus cereus & Escherichia coli was evaluated by microwell dilution method to determine MIC & MBC values. The present work aimed to chemically characterize & evaluate the antiradical power & biological effects of Citrus medica var.

   • Selon Selvaraju N (2022)

     Excerpt This work reports on the synthesis of prominent members of the carbon family, carbon quantum dots (CQDs), from a natural carbon precursor, Citrus medica fruit, & their inhibiting property against P. Pseudomonas aeruginosa (P.

   • Selon Aliberti L (2016)

     Excerpt The antimicrobial activity of the EOs was assayed against some bacterial strains: Bacillus cereus (DSM 4313), Bacillus cereus (DSM 4384), Staphylococcus aureus (DSM 25693), Pseudomonas aeruginosa (ATCC 50071), & Escherichia coli (DSM 8579). The antimicrobial activity registered confirm their traditional uses as food preserving agents & led us to hypothesize the possible use of these oils as antimicrobials.

   • Selon Hasan MM (2022)

     Excerpt Therefore, experiments were carried out to test the antibacterial activity of methanolic extracts of peels from various locally available citrus fruits such as citron (Citrus medica), satkora (Citrus macroptera) & adajamir (Citrus assamensis) against Bacillus spp. Citrus fruits can be exploited as antibacterial & antioxidant ingredients in food & nutraceuticals,

   • Excerpt according to the findings of this study.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.