Plectranthus amboinicus (Gwo-diten) : propiedades medicinales en extracción alcohólica

Plectranthus amboinicus (Gwo-diten, Tomillo grande, Gros-thym, Large thyme) — familia Lamiacées.

Sinónimos científicos : Coleus amboinicus-Lour., C aromaticus-Benth..

Fuentes externas reconocidas asociadas a esta monografía: TRAMIL y Farmacopea francesa.

Esta base documenta las extracciones alcohólicas (etanol) de las sustancias activas. Nuestra monografía recoge actualmente 23 indicaciones en extracción alcohólica para esta especie. El catálogo Lapo v2 registra 75 referencias científicas para esta especie (detalle completo en la aplicación).

Indicaciones terapéuticas en extracción alcohólica:

Importante — referencias científicas en esta página pública: solo se muestra un breve extracto de cada fuente citada (frases de resumen seleccionadas), conservado en el idioma original de la publicación (casi siempre el inglés), sin traducir. Estos extractos no constituyen el texto íntegro del artículo ni una bibliografía completa. Las fichas de referencia completas y el detalle monográfico están disponibles en la aplicación Lapo v2 (prueba gratuita de 30 días).

1. 1

   Infección bacteriana: Aeromonas hydrophila, Edverchila tarda, Enterobacter aerogenes, Flavobacterium, Escherichia coli, Proteus mirabilis, Staphylococcus aureus, Pseudomonas aeruginosa, Klebsiella pneumoniae

   Parte usada: raíz.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon MUNIANDY K (2014)

     Extrait aromaticus demonstrated good antibacterial activity against Escherichia coli, Proteus mirabilis & Staphylococcus aureus & moderate activity against Pseudomonas aeruginosa & Klebsiella pneumonia. This antibacterial study indicates the crude extract as a bioactive compound that could be useful to develop new antimicrobial agents & it can be used to assist us in reducing the burden of cost & drug resistance.

   • Selon Auteur (2016)

     Extrait or Plectranthus amboinicus Lour. This article is an effort to compile the information reported on its antimicrobial activities.

   • Selon Nirmala D (2008)

     Extrait amboinicus has antimicrobial & antifungal activity. Further investigation in the isolation & purification of the active principle responsible for the activity may provide an antimicrobial, antifungal along with antileptospiral activity drug Template from natural source.

   • Selon Auteur (1998)

     Extrait Rasmi A, Antiviral activity against Herpès Simplex Virus type 2 of extracts from Cerbera odollam Gaertn., Clausena excavata Burm. F., Coleus amboinicus Lour., Phyla nodiflora (L.) Greene & Thevetia peruviana Schum, MSc.

   • Selon Dos Santos NO (2015)

     Extrait Dos Santos NO et al, Assessing the chemical composition & antimicrobial activity of essential oils from Brazilian plants—Eremanthus erythropappus (Asteraceae), Plectranthus barbatus, & P.

2. 2

   Cáncer: tratamiento adyuvante del sarcoma

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Gurgel AP (2009)

     Extrait Plectranthus amboinicus (Lour.) Spreng is a medicinal specie often used in Brazil, especially in Northeast Region, for the treatment of several diseases including inflammations and cancer. amboinicus at the doses of 100, 150, 250 & 350 mg/kg (i.p.) inhibited the growth of sarcoma-180 & Ehrlich Ascite carcinoma tumors in mice.

   • Selon Hasibuan PAZ (2019)

     Extrait Conclusions: The P amboinicus leaves Ethanolic Extract Nanoparticles could be an effective anticancer by improving its downregulation on cyclinD1, upregulation caspase-9 & p53. The application of nanotechnology is aimed to enhance the capability of the chemical compounds of Plectranthus amboinicus leaves activity.

   • Selon Manurung K (2020)

     Extrait Conclusions : All the flavonoid compounds contained in the ethanolic extract of P amboinicus leaves exhibit very strong anti-cancer & antioxidant activity, which results in ethanolic extract of P amboinicus leaves have very strong antioxidant activity. The results showed that the flavonoid compounds contained in P amboinicus have similar anticancer activity to the reference molecule at the P-Glycoprotein-1, Cyclin Dependent Kinase-2, & Phosphoinositide-3-Kinase receptors, as well as better anticancer activity than the reference molecule for the Cyclooxygenase-2 & Phosphoenolpyruvate Carboxykinase receptors.

   • Selon Hasibuan PAZ (2017)

     Extrait Results: Treatment with P amboinicus (ethanolic extract nanoparticles (PAEEN) inhibited the proliferation of T47D cell lines after 48 hours & 72 hours of incubation at concentrations of 22.3 μg/mL, 44.6 μg/mL, & 89.2 μg/mL. Plectranthus amboinicus (Lour.) Spreng.

   • Selon Leo caroline M (2022)

     Extrait Studies show that the two medicinal herbs Plectranthus amboinicus (Indian borage, Karpooravalli) & Glycyrrhiza glabra (Liquorice, Athimathuram) have shown excellent anticancer activity on various cancers. The present study aimed to evaluate & assess the anticancer property of two medicinal plants PA & GG on oral cancer (KB) cell line.Materials & Methods: Ethanolic extracts of leaves of PA & roots of GG were prepared.

3. 3

   Infección viral: herpes simple

   Parte usada: Hoja.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (1998)

     Extrait Rasmi A, Antiviral activity against Herpès Simplex Virus type 2 of extracts from Cerbera odollam Gaertn., Clausena excavata Burm. F., Coleus amboinicus Lour., Phyla nodiflora (L.) Greene & Thevetia peruviana Schum, MSc.

   • Selon Auteur (2016)

     Extrait or Plectranthus amboinicus Lour. This article is an effort to compile the information reported on its antimicrobial activities.

   • Selon Nirmala D (2008)

     Extrait amboinicus has antimicrobial & antifungal activity. Further investigation in the isolation & purification of the active principle responsible for the activity may provide an antimicrobial, antifungal along with antileptospiral activity drug Template from natural source.

   • Selon Dos Santos NO (2015)

     Extrait Dos Santos NO et al, Assessing the chemical composition & antimicrobial activity of essential oils from Brazilian plants—Eremanthus erythropappus (Asteraceae), Plectranthus barbatus, & P.

   • Selon Ragasa CY (1999)

     Extrait Antimicrobial flavones from Coleus amboinicus.

Otras indicaciones (incluidos otros modos de extracción si procede), posologías, precauciones de uso y las <strong>referencias científicas completas</strong> (fichas íntegras, no solo los extractos cortos anteriores) están disponibles en la ficha monográfica de la aplicación Lapo v2.