Foeniculum vulgare (Fenouil) : vertus médicinales en extraction alcoolique

Foeniculum vulgare (Fenouil, Fennel) — famille Apiacées.

Synonymes scientifiques : Foeniculum vulgare-(L)-Karst.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 17 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 101 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer traitement adjuvant du carcinome hépatique & pulmonaire

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon KE W (2021)

     Extrait Studies have shown that various Foeniculum vulgare (fennel) extracts exhibit anti-cancer effects on malignant tumors such as skin cancer & prostate cancer. Hepatocellular carcinoma (HCC) is one of the most common malignant tumors.

   • Selon Auteur (2017)

     Extrait The biochemical analyses of hepatic enzymes were evaluated by estimating blood biomarkers of liver & renal damage along with histological examination. Foeniculum vulgare (Apiaceae) is commonly known as fennel.

   • Selon OZbêck H (2004)

     Extrait Hepatoprotective activity of Foeniculum vulgare (fennel) essential oil was studied using a carbon tetrachloride-induced liver fibrosis model in rats. The results of this study clearly indicate that F vulgare essential oil has a potent hepatoprotective action against carbon tetrachloride-induced liver fibrosis in rats.

   • Selon Ozbek H (2003)

     Extrait Hepatoprotective activity of Foeniculum vulgare (Fennel) essential oïl (FEO) was studied using carbon tetrachloride (CCl (4)) induced liver injury model in rats. The results of this study indicate that FEO has a potent hepatoprotective action against CCl (4)-induced hepatic damage in rats.

   • Selon Ghanem V (2012)

     Extrait Phenolic compounds from Foeniculum vulgare (Subsp. Piperitum) (Apiaceae) herb & evaluation of hepatoprotective antioxidant activity.

2. 2

   Cancer : traitement adjuvant du carcinome : mammaire, prostatique, utérin, leucémique

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Binneman B (2008)

     Extrait A naphthoquinone, 7-methyljuglone and some of its 5-hydroxy, 5-acetoxy-, 5-alkoxy- & 1,2,4,5-tetra-O-acetate derivatives were tested for their activity in four human cancer cell lines: breast adenocarcinoma, cervical epithelial carcinoma, oesophageal carcinoma and prostate epithelial carcinoma. Of all the ethanol extracts, Foeniculum vulgare was found to have the best activity on HeLa cells, which exhibited an IC50 value of 19.97± 0.048 µg/ml.

   • Selon KE W (2021)

     Extrait Studies have shown that various Foeniculum vulgare (fennel) extracts exhibit anti-cancer effects on malignant tumors such as skin cancer & prostate cancer. Collectively, in vivo & in vitro results suggest that FVE exerts inhibitory effects in HCC by targeting the oncoprotein survivin, suggesting FVE may be a potential anti-cancer agent that may benefit patients with HCC.

   • Selon KE W (2021)

     Extrait Various extracts of Foeniculum vulgare have shown promising anticancer activity; however, effects on lung cancer & the underlying molecular mechanisms of action are not clear. Taken together, these findings suggest that EEFS exerts anti-lung cancer activity by targeting the Bcl-2 protein & may have potential as a therapeutic drug for lung cancer.

   • Selon Auteur (2017)

     Extrait It is concluded that fennel oil has various pharmacological properties including antioxidant, anti-cancer activity, anti-inflammatory. Foeniculum vulgare (Apiaceae) is commonly known as fennel.

   • Selon Namrita L (2015)

     Extrait The results showed that compound 2 showed high toxicity against all the cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg/mL, respectively. vulgare was found to exhibit the most significant toxicity with an IC50 value of 19.97 μg/mL on HeLa cells.

3. 3

   Atrophie vaginale chez la femme ménauposée

   Partie usitée : Semence.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Yaralizadeh M (2016)

     Excerpt CONCLUSION:

   • Excerpt According to results of this study, Fennel is an effective means to manage the symptoms of vaginal atrophy in postmenopausal women & is devoid of side effects. The aim of the present study was to investigate the effect of Fennel vaginal cream on vaginal atrophy in postmenopausal women in Ahvaz, Iran.

   • Selon Auteur (2019)

     Excerpt This review paper evaluates use of Foeniculum vulgare extracts as a popular female plant in management of different ailments of women. Topical & vaginal fennel extract (5%) exhibited good efficacy in treatment of sexual function, vaginal atrophy & hirsutism.

   • Selon Pourjafarr A (2019)

     Excerpt The present study was conducted to investigate the protective effects of fennel & flaxseed during pre- & post-natal period until puberty & menopause on ovarian follicular reserve (OFR). Conclusions: It can be concluded that fennel alone & in combination with flaxseed could improve OFR during pregnancy, lactation & afterwards until puberty & menopause.

   • Selon Javidnia K (2003)

     Excerpt Fennel, Foeniculum vulgare, is a plant, which has been used as an estrogenic agent. Idiopathic hirsutism is defined as the occurrence of excessive male pattern hair growth in women who have a normal ovulatory menstrual cycle and normal levels of serum androgens.

   • Selon Karampoor P (2014)

     Excerpt Fennel (Foeniculum vulgare) has estrogenic, anti-inflammatory & antioxidant effects & traditionally used for treatment of infertile women. Polycystic Ovarian Syndrome (PCOS) is the most common endocrine disorder in women, which affects 5-10% of them in their reproductive age.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.