Houttuynia cordata (Pwèv-Chin) : vertus médicinales en extraction alcoolique

Houttuynia cordata (Pwèv-Chin, poivre de Chine, Chinese pepper) — famille Saururacées.

Synonymes scientifiques : Houttuynia cordata f. viridis-Ohara, H emeiensis-ZY Zhu & SL Zhang, H foetida-Loudon, Polypara cordata -Kuntze..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 17 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 193 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon SAKULUDOMKAN W (2021)

     Extrait This study aimed to investigate the antidiabetic effects of fermented HC in high-fat diets & streptozotocin-induced diabetic rats. Taken together, these results demonstrate that HC can improve diabetic symptoms by enhancing insulin sensitivity, reducing oxidative stress, & suppressing inflammation.

   • Selon RAHMAN SS (2025)

     Extrait To induce diabetes, the rats received an intraperitoneal injection of streptozotocin. Objectives: This research aimed to determine the key bioactive components in the ethanolic extract of HC (HCEE) responsible for its thyroid-modifying properties & examine its effects on rats with experimentally induced hypothyroidism & diabetes.

   • Selon RAHMAN S (2024)

     Extrait This study aimed to explore the potential antidiabetic & hypolipidemic effects of Plu kaow (Houttuynia cordata Thunb.) ethanolic extract (PK) in streptozotocin (STZ) induced diabetic rats, focusing on its molecular mechanisms. In conclusion, PK shows promise as a potential treatment or management option for diabetes & hyperlipidemia, as well as their associated complications in diabetic rats.

   • Selon Auteur (2022)

     Extrait Houttuynia cordata is a traditional medicinal plant that is widely distributed in East Asia. Apart from its consumption as a delicacy in many countries, it has a rich history of medicinal use and numerous studies have reported its pharmacological activity against inflammation, cancer, viruses, bacteria, hyperglycaemia, obesity, etc.

   • Selon Hsu CC (2016)

     Extrait The anti-glycative & anti-oxidative effects from Houttuynia cordata leaves aqueous extract (HCAE) in heart & kidney of diabetic mice were examined. HCAE reduced reactive oxygen species, protein carbonyl, interleukin-6, tumor necrosis factor-alpha, N ε-(carboxymethyl)-lysine, pentosidine & fructose levels, & reserved glutathione content in heart & kidney of diabetic mice (P < 0.05).

2. 2

   Troubles hépatiques

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Chen HL (2021)

     Extrait Houttuynia cordata has been used as a traditional medicine for more than 1500 years. However, long-term use of HCE with large doses exhibited some hepatotoxicity & nephrotoxicity in rats,.

   • Selon Kim OK (2002)

     Extrait This study was performed to investigate the protective effect of Houttuynia cordata Thunb on hepatotoxicity in carbon tetrachloride (CCl4) intoxicated rats. The examined effects hexane, chloroform, butanol & water fractions prepared from the Houttuynia cordata Thunb methanol extract & rats were administrated with those orally once a day for successive 6 days, followed by treatment with CCl4 on the sixth day.

   • Selon Chen H (2021)

     Extrait Houttuynia cordata has been used as a traditional medicine for more than 1500 years. However, long-term use of HCE with large doses exhibited some hepatotoxicity & nephrotoxicity in rats.

   • Selon Tian L (2012)

     Extrait This study was designed to investigate the antioxidant activity, hepatoprotective effect, & phenolic composition of the ethyl acetate fraction (EAF) extracted from Houttuynia cordata tea. These results combined with liver histopathology indicate that EAF possesses a significant protective effect against acute hepatotoxicity induced by CCl4, which may be due to the strong antioxidant activity of phenolic components.

   • Selon SUKAR S (2023)

     Extrait Houttuynia cordata (Thunb.), an important medicinal plant of Northeast India, Korea, & China, is used to treat various ailments & for anticancer research. Network pharmacology analysis of the 14 compounds showed interaction with 232 different targets with their potential involvement in hepatocellular carcinoma.

3. 3

   Cancer : carcinome cutané squameux

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Gao L (2021)

     Extrait Most of reports of its anti-cancer activity were conducted in vitro, & its effects on cutaneous squamous cell carcinoma (SCC) has not been investigated yet. Houttuynia cordata Thunb (HCT) is a medicinal & edible herb which has beneficial effects on various diseases due to its diuretic, anti-inflammatory, anti-oxidative, anti-microbial, anti-viral, anti-cancer & anti-diabetic properties.

   • Selon SUKAR S (2023)

     Extrait Houttuynia cordata (Thunb.), an important medicinal plant of Northeast India, Korea, & China, is used to treat various ailments & for anticancer research. Whole extracts impart cytotoxicity on variety of cell lines including HepG2.

   • Selon Subhawa S (2020)

     Extrait In this study, the inhibitory effects of HCT & PR ethanolic extracts on breast cancer cell proliferation, migration, invasion & apoptosis were examined. Additionally, HCT & PR extracts also decreased the migration & invasion of both breast cancer cell lines through inhibition of MMP-2 & MMP-9 secretion.

   • Selon Pawinwongchai J (2011)

     Extrait Houttuynia cordata, a local plant in Northern Thailand, has many biological activities including anti-cancer, antileukemic, anti-microbial, anti-oxidant, anti-inflammatory & immunomodulatory effects. In addition, our cytokine study found that Hc extract especially HC ethanolic extract substantially reduced the Tumor Necrosis Factor-alpha (TNF-α).

   • Selon CHEN YF (2021)

     Extrait Conclusions: The anti-tumor effects of aristolactam BII, aristolactam AII, & noraristolodione on human lung carcinoma A549 cells were via cell cycle arrest & apoptosis. A549 lung cancer cell line was used to evaluate the effects of HC on the cell viability & possible anti-tumor effects.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.