Hymenaea courbaril (Koubari) : vertus médicinales en extraction alcoolique

Hymenaea courbaril (Koubari, Courbaril) — famille Caesalpiniacées.

Synonymes scientifiques : Hymenaea animifera Stokes, Hcandolleana Kunth, H multiflora Kleihoonte, H resinifera Salisb., H retusa Hayne.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 69 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Infection bactérienne : Staphylococcus aureus

   Partie usitée : Pelure du fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Scaramusa SA (2022)

     Extrait Combining the 70% ethanol extracts from peels & seeds reduced their inhibitory concentration by about 4 to 32 times against Bacillus cereus, Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, P. In this work, the in vitro antioxidant & antimicrobial potential of hydroalcoholic extracts from the peel &seeds of jatobá fruit & the synergistic effect of their combination against pathogenic bacteria were evaluated.

   • Selon Narvaez Correa M (2020)

     Extrait The assessment of the antimicrobial activity of Hymenaea courbaril on different microorganisms was realized with four bacteria, Escherichia coli, Staphylococcus aureus, Bacillus subtilis, & Pseudomonas aeruginosa, two yeasts Candida albicans & Saccharomyces cerevisiae, and finally two filamentous fungi Aspergillus niger. (jatobá) em camundongos tratados com acetaminophen, Rev Cubana de Plantas Med, 2020, 25: e752-Abstract: Hymenaea courbaril L.

   • Selon LOZANO CM (2021)

     Extrait The objective of this study was to evaluate the antimicrobial activity of crude ethanolic extracts of 48 medicinal plants collected at regional or municipal markets in Dominican Republic for the treatment of several types of infections associated diseases. Conclusion: Several ethanolic crude extracts derived from plants used in traditional medicine in the Dominican Republic possess antimicrobial activity against a variety of the tested micro-organisms.

   • Selon Cruz JER (2023)

     Extrait In this context, the present study aimed to determine the total phenolic content, antioxidant capacity, & antimicrobial & anti-biofilm potential of nine extracts of Hymenaea courbaril (Fabaceae), popularly known as Jatobá. Therefore, these results showed the potential use of HC as an antioxidant & point to its use in antimicrobial therapy with an anti-biofilm effect.

   • Selon De Brito M.S (2016)

     Extrait Partial Purification of Trypsin/Papain Inhibitors from Hymenea courbaril L. Seeds & Antibacterial Effect of Protein Fractions Materials & Methods.

2. 2

   Cancer : traitement adjuvant du mélanome

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Lisboa EM de J (2021)

     Extrait Male Swiss mice (n=6) were subcutaneously inoculated with 106 tumor cells & intragastrically administered ethanol (2 mg·mL-1, 5 mg·mL-1, or 10 mg·mL-1) or aqueous extracts of HC seed or bark for 90 days. Tumor development did not significantly differ between the groups studied; however, animals treated with the aqueous extract of the seed (2.205 mg·mL-1) had a reduction in tumor size compared to those treated with the aqueous extract of the bark (1.7 mg·mL-1).

   • Selon Abdel-Kader M (2002)

     Extrait Bioactivity-directed fractionation of a methanol extract of Hymenaea courbaril afforded the three new diterpenoids (13R)-13-hydroxy-1(10),14-ent-halimadien-18-oic acid (1), (2S,13R)-2,13-dihydroxy-1(10),14-ent-halimadien-18-oic acid (2), & (13R)-2-oxo-13-hydroxy-1(10),14-ent-halimadien-18-oic acid (3). Compound 1 exhibited weak cytotoxicity toward the 1138 mutant yeast strain & the A2780 human ovarian cancer cell line.

   • Selon Delgado C (2021)

     Extrait Hymenaea courbaril L. has been used in traditional medicine in South America to treat several diseases, including prostate cancer.

   • Selon Carneiro-Lobo LA (2025)

     Extrait courbaril) is a South American native species frequently used to treat various symptoms & illnesses, including anemia, fatigue, inflammation, pain, respiratory conditions, kidney & prostate disorders, cancer, diabetes, arthritis, rheumatism, gastric & hepatic dysfunctions, & skin conditions. Hymenaea courbaril L.

   • Selon SPERA KD (2010)

     Extrait Hymenaea courbaril has been used to treat different diseases, although its properties are yet to be scientifically validated. The results allowed us to also infer that the hydroethanolic extract from seeds shows cytotoxic activity against B16F10 melanoma cells line & it has dose-&-time-dependency.

3. 3

   Arthrose, arthrite, rhumatisme, oedème

   Partie usitée : écorce de tige.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Bezerra GP (2013)

     Extrait Aim of the study: In order to give a scientific basis to support the traditional use of HC this study was designed to evaluate antioxidant, myorelaxant & anti-inflammatory properties of the ethanol extract from stem bark & its fractions. The following activities were investigated: antioxidant by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay, myorelaxant on rat tracheal smooth muscle, & anti-inflammatory using ovalbumin-induced leukocytosis & airway hyperresponsiveness in rats.

   • Selon Jayaprakasam B (2007)

     Extrait Stinking toe (Hymenaea courbaril), also called Jatobá & Kerosene tree, is a medicinal plant commonly found in the central & South American countries. Compounds 1–5 and 7 were assayed for anti-inflammatory activity using cyclooxygenase-1 (COX-1) & -2 (COX-2) enzymes.

   • Selon Massae Hata M (2017)

     Extrait Massae Hata M et al, Anti-inflammatory effects of Hymenaea courbaril essential oil compounds on pterygium fibroblasts, Investigative Ophthalmol & Visual Sci, 2017, 58(8): The search for new drugs has found in plants an important source of biologically active compounds. The Hymenaea courbaril is a tree that grows in South America forests & it’s essential oil has proved anti-inflammatory effects.

   • Selon Vigilato-Rodriguez MA (2021)

     Extrait Jatobá resin is a product of Hymenaea genus trees with antimicrobial & anti-inflammatory activities, interesting properties for films applied in several areas.

   • Selon Carneiro-Lobo LA (2025)

     Extrait courbaril) is a South American native species frequently used to treat various symptoms & illnesses, including anemia, fatigue, inflammation, pain, respiratory conditions, kidney & prostate disorders, cancer, diabetes, arthritis, rheumatism, gastric & hepatic dysfunctions, & skin conditions. Hymenaea courbaril L.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.