Luffa acutangula (Tòchon) : vertus médicinales en extraction alcoolique

Luffa acutangula (Tòchon, torchon, Éponge végétale, Pitenga, tea towel, plant-based sponge) — famille Cucurbitacées.

Synonymes scientifiques : Cucumis acutangulus-Linn. C lineatus-Bosc, C megacarpus-G.Don, Luffa acutangula-(L.), L amara-Roxb., Momordica tubiflora-Wall..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 87 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Fruit. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Raj SM (2012)

     Extrait The Antidiabetic activity of fruits & seeds ethanolic extract of Luffa acutangula (Cucurbitaceae) was studied in a Streptozotocin {STZ) induced diabetic in rats. The 50% ethanolic extract of the fruits of Luffa acutangula showed the significant effect compared with the respective diabetic control group, decrease the blood glucose level at a dose of 200 mg/kg & 400 mg/kg (p<0.001), the standard drug Glibenclamide also showed the significant decrease the blood glucose level after 21 days (241.33-105.33, p<0.001).

   • Selon Mohan Raj S (2012)

     Extrait The Antidiabetic activity of fruits & seeds ethanolic extract of Luffa acutangula (Cucurbitaceae) was studied in a Streptozotocin {STZ) induced diabetic in rats. The results showed that the extract (200 & 400 mg/kg) significantly (P<0.05) reduced fasting blood sugar of Streptozotocin diabetic rats in a dose-related manner, with maximum hypoglycemic effect at after 21 days.

   • Selon Pimple B (2011)

     Extrait Pimple B et al, Antidiabetic & antihyperlipidemic activity of Luffa acutangula fruit extracts in streptozotocin induced NIDDM rats.

   • Selon Quanico JP (2008)

     Extrait Quanico JP et al, Analgesic & hypoglycemic activities of Bixa orellana, Kyllinga monocephala & Luffa acutangula.

   • Selon GHANE SG (2022)

     Extrait Luffa acutangula (Roxb.) L. Fruits represent number of promising bioactivities such as antioxidant, anticancer, antidiabetic, antimicrobial, larvicidal etc.

2. 2

   Cirrhose, hépatite, stéatose hépatique

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Mishra B (2017)

     Extrait The alcoholic extract of fruits of the plant Luffa acutangula previously reported for is hepatoprotective activity was fractionated into three parts to chemically identify the most potent bioactive fraction. The hepatoprotective potential of the fraction prepared from extract was studied in vivo in rats as well as ex vivo in isolated hepatocytes against paracetamol induced hepatotoxicity.

   • Selon Ibrahim M (2014)

     Extrait Ibrahim M et al, Phytochemical & hepatoprotective activity of fruit extracts of Luffa acutangula Roxb.

   • Selon Abid M (2014)

     Extrait Abid M et al, Phytochemical & hepatoprotective activity of fruit extracts of Luffa acutangula Roxb var amara.

   • Selon Jadhav VB (2010)

     Extrait Hepatoprotective activity of hydroalcoholic extract of Luffa acutangula (HAELA) against carbon tetrachloride (CCl4) and rifampicin-induced hepatotoxicity in rats was evaluated & probable mechanism(s) of action has been suggested. Hepatoprotective activity of HAELA was due to the decreased levels of serum marker enzymes viz., (AST, ALT, ALP and LDH) and increased total protein including the improvement in histoarchitecture of liver cells of the treated groups as compared to the control group.

   • Selon Ulaganathan I (2010)

     Extrait Ulaganathan I et al, Protective effect of Luffa acutangula (var) amara against carbon tetrachloride induced hepatotoxicity in experimental rats.

3. 3

   Cancer : traitement adjuvant du lymphome

   Partie usitée : Fruit. Profil pharmacologique documenté : Cisplatine-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Dashora N (2015)

     Extrait Dashora N et al, In vitro antioxidant & in vivo anti-tumor activity of Luffa acutangula against Dalton’s Lymphoma Ascites (DLA) cells bearing mice.

   • Selon Reddy BP (s.d.)

     Extrait Reddy BP et al, Antiproliferative & antiangiogenic effects of partially purified Luffa acutangula fruit extracts on human lung adenocarcinoma epithelial cell line, Current Trends in Biotechnol & Pharm,.

   • Selon Dashora N (2015)

     Extrait The objective of the present study is to explore the anticancer activity of the ethanolic & aqueous extracts of the Luffa acutangula in Swiss albino mice against Ehrlich Ascites Carcinoma (EAC) cell line. After 24 h of the last dose & then eighteen hours of fasting, the mice were sacrificed & antitumor effect of ETOH & aqueous extracts was assessed by evaluating tumor volume, viable & nonviable tumor cell count, tumor weight & hematological parameters of EAC bearing host.

   • Selon Vanajothi R (2015)

     Extrait Luffa acutangula (Cucurbitaceae) is widely used as a traditional medicine in India & was reported to possess various pharmacological activities including its anti-proliferative effects. Five major fractions were collected & evaluated for their anti-proliferative activity against non-small cell lung cancer cells (NCI-H460).

   • Selon Petropoulos SA (2021)

     Extrait Luffa oil was the most effective against two of the tested cancer cell lines, namely HeLa (cervical carcinoma) & NCI-H460 (non-small cell lung cancer), while it also showed moderate toxicity against non-tumor cells (PLP2 cell line). In regards to particular oils, linseed oils were a rich source of α-linolenic acid, luffa & pumpkin oil were abundant in linoleic acid, while purslane oil presented a balanced composition with an almost similar amount of both fatty acids.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.