Pennisetum purpureum (Zèb-léfan) : vertus médicinales en extraction alcoolique

Pennisetum purpureum (Zèb-léfan, Herbe-à-éléphant, Merker, Elephant grass) — famille Poacées.

Synonymes scientifiques : Cenchrus purpureus (Schumach.) M, Gymnotrix nitens-Andersson, Pennisetum benthamii Steud..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 5 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 38 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : chemoprevention du carcinome pulmonaire à petite cellule

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Flora TM (2018)

     Extrait Conclusions: Some of the tested plants namely Albizia adianthifolia, Alchornea cordifolia, Alchornea laxiflora, Pennisetum purpureum, Spathodea campanulata represent a potential source of novel anticancer drugs. Results: In the preliminary assay using CCRF-CEM cells, 12 extracts from five plants displayed IC50 values below 80 μg/mL, namely Albizia adianthifolia, Alchornea cordifolia, Alchornea laxiflora, Pennisetum purpureum, & Spathodea campanulata.

   • Selon Chen Y (2020)

     Extrait 2 (NT2) is a new hybrid of napiergrass (Pennisetum purpureum S.), & Is commonly added as an ingredient in bioorganic energy soup, a plant-based drink which is thought to have health-promoting effects. The ethanol extracts did not show immunomodulatory activities in macrophages without lipopolysaccharide (LPS, 100 ng/ml) treatment, but significantly suppressed the LPS-stimulated production of inflammatory mediators, including nitric oxide (NO), interleukin (IL)-6, & tumor necrosis factor (TNF)-α, & such effects were associated with decreased expression of inducible NO synthase (iNOS) protein & cluster of differentiation 14 (CD14) mRNA, suggesting that NT2 has anti-inflammatory activities.

   • Selon Chinedu O (2010)

     Extrait The fresh leaf samples of Pennisetum purpureum has been shown to be a potential source of dietary protein & antioxidants.

   • Selon Akuru UB (2015)

     Extrait Phytochemical composition & antidiabetic properties of aqueous stem extract of Pennisetum purpureum on alloxan –induced diabetic wistar-albino rats was assessed. There was significant (p<0.05) reduction in triglyceride, very low density lipoprotein & white blood cell levels while high density lipoprotein level, cholesterol &low density lipoprotein level have no significant difference (p>0.05).

   • Selon Bajaj G (2011)

     Extrait The leukocyte count of calves increased (P<0.01) from 9.68 to 16.92x10/mm3with significantly decrease in packed cell volume from 31.80 to 26.67 & slight increase in haemoglobin from 10.47 to 10.92 g/dl.

2. 2

   Arthrose, arthrite, rhumatisme, oedème

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ali K (2015)

     Extrait The finding in this study indicates that PG extracts have potential effects as an antioxidant and anti-inflammatory activities against inflammation & free radicals in all tests. The anti-inflammatory activity of aqueous extract of PG (AEPG) was evaluated in rats, using carrageenan induced edema, & indomethacin (10 mg/kg) was used as reference drug.

   • Selon Chen Y (2020)

     Extrait The ethanol extracts did not show immunomodulatory activities in macrophages without lipopolysaccharide (LPS, 100 ng/ml) treatment, but significantly suppressed the LPS-stimulated production of inflammatory mediators, including nitric oxide (NO), interleukin (IL)-6, & tumor necrosis factor (TNF)-α, & such effects were associated with decreased expression of inducible NO synthase (iNOS) protein & cluster of differentiation 14 (CD14) mRNA, suggesting that NT2 has anti-inflammatory activities. In conclusion, ethanol extracts of NT2 possessed in vitro antioxidative activities & exhibited anti-inflammatory activities by decreasing NO, IL-6, & TNF-α production in association with decreased CD14 mRNA expression in LPS-induced RAW 264.7 macrophages, indicating its potential roles on health promotion & prentive effects against chronic diseases & such effects were & it’s in vitro antioxidant activities, suggesting its potential roles on health promotion.

   • Selon Oluwefemi Adekelo Ojo (2022)

     Extrait The crude extracts were found to have antioxidant, antimicrobial, anti-cytotoxic, anti-hypertensive, & anti-inflammatory properties. The genus Pennisetum contains remarkable natural bioactive components, & its 140 species are widely distributed in tropical & subtropical countries, where they are frequently used for therapeutic purposes such as the treatment of dysentery, fever, diabetes, & abdominal pain by indigenous people.

   • Selon Chinedu O (2010)

     Extrait The fresh leaf samples of Pennisetum purpureum has been shown to be a potential source of dietary protein & antioxidants. In this study, the anti-gastric acid effect of fresh leaf samples of achara Ibeku was determined by inducing ulcer with ethanol.

   • Selon Chinedu O (2015)

     Extrait There is dearth of information on possible anti-ulcerogenic effect of methanolic extract of edible young leaves of Napier grass (Pennisetum purpureum). The fresh leaf samples of Pennisetum purpureum has been shown to be a potential source of dietary protein a&antioxidants.

3. 3

   Douleur, hyperalgie

   Partie usitée : Feuille. Profil pharmacologique documenté : Aspirine-like, Acetaminophène-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Igbokwe E (2015)

     Extrait Pennisetum purpureum (Elephant or Napier grass) is being used in East Africa & some other parts of the world as animal feed & also in pulp industry. The study is aimed at evaluating the analgesic activity of the ethanol extract of PP in experimentally induced acetic acid writhing in mice.

   • Selon Oluwefemi Adekelo Ojo (2022)

     Extrait The genus Pennisetum contains remarkable natural bioactive components, & its 140 species are widely distributed in tropical & subtropical countries, where they are frequently used for therapeutic purposes such as the treatment of dysentery, fever, diabetes, & abdominal pain by indigenous people. Aim of the review: The current review provides a profound perception, enhanced understanding, & comprehensive information on the traditional uses, phytochemical compounds, and biological activities of the genus Pennisetum, as well as toxicological perspectives.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.