Acanthospermum hispidum (Tèt-bèf) : vertus médicinales en extraction alcoolique
Acanthospermum hispidum (Tèt-bèf, Chivé-Zonbi, tète-à-bœuf, Cheveux-à-Zombi, Ox-head, Zombie-hair) — famille Astéracées.
Synonymes scientifiques : Acanthospermum humile var. Hispidum -(DC)-Kunth.
Sources externes reconnues associées à cette monographie : TRAMIL.
Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 6 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 21 références scientifiques pour cette espèce (détail intégral dans l’application).
Indications thérapeutiques en extraction alcoolique :
Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).
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Infection bactérienne : Bacillus subtilis, Klebsiella pneumoniae, Proteus vulgaris, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon ADUE F (2011)
Extrait The extract demonstrated antibacterial activity against Staphylococcus aureus, Klebsiella pneumoniae, Bacillus subtilis, Salmonella typhi, Proteus vulgaris & Pseudomonas aeruginosa with MICs ranging between 11 and 53 mg/ml. The effect of the sub-inhibitory concentrations of Acanthospermum hispidum extract on the activities of amoxicillin and ciprofloxacin was assessed by the Kirby-Bauer disc diffusion method.
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Selon GOMATHI V (2013)
Extrait The ethanolic extract of whole plant of Acanthospermum hispidum DC exhibited significant antioxidant activity by total antioxidant activity assay, nitric acid free radical scavenging activity assay, reducing power assay and hydrogen peroxide free radical scavenging assay. The present study was carried out to preliminary phytochemical and antioxidant activity of whole plant of Acanthospermum hispidum DC.
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Selon ADUE F (2011)
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Cancer : traitement adjuvant du carcinome lymphatique
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Deepa N (2007)
Extrait (2007) investigated the antitumor activity of 50% aqueous ethanol extract of Acanthospermum hispidum DC against Dalton’s ascites Lymphoma in mice. Thus, it is suggested that Acanthospermum hispidum DC appears promising for the development of Phytomedicine for the treatment of cancer.
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Selon GOMATHI V (2013)
Extrait The ethanolic extract of whole plant of Acanthospermum hispidum DC exhibited significant antioxidant activity by total antioxidant activity assay, nitric acid free radical scavenging activity assay, reducing power assay and hydrogen peroxide free radical scavenging assay. The present study was carried out to preliminary phytochemical and antioxidant activity of whole plant of Acanthospermum hispidum DC.
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Selon ADUE F (2011)
Extrait The effect of the sub-inhibitory concentrations of Acanthospermum hispidum extract on the activities of amoxicillin and ciprofloxacin was assessed by the Kirby-Bauer disc diffusion method. hispidum appears to contain Phytoconstituents that may be useful adjuvant for antibiotic formulations.
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Selon Deepa N (2007)
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Infection fongique : candidiase
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Chakraborty AK (2012)
Extrait A scrutiny of the literature revealed some notable pharmacological activities of the drug like antimicrobial, antifungal, antiviral, Anthelmintic, immunomodulator, Abortifacient, Antitrypanosomal and Antileishmanial. The present review is an attempt to highlight the various ethnobotanical and traditional uses as well as the various phytochemical and pharmacological reports on Acanthospermum Hispidum.
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Selon Arena ME (2011)
Extrait Arena ME et al: In vivo & in vitro Antibacterial activity of acanthospermal, B, a sesquiterpene lactone isolated from Acanthospermum hispidum.
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Selon Theresa IE (2011)
Extrait Theresa IE et al: Two Flavones from Acanthospermum Hispidum DC & their Antibacterial Activity.
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Selon Summerfield A (1997)
Extrait Summerfield A et al, Antiviral activity of an extract from leaves of the tropical plant Acanthospermum hispidum.
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Selon Fleischera TC (2003)
Extrait The ethanolic extracts of the leaves and flowering tops of Acanthospermum hispidum showed varying degrees of activity against a wide range of pathogenic bacteria.
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Selon Chakraborty AK (2012)
D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.
Évolution de cette fiche publique
Sous le CTA · journal des mises à jour
+1 indication · −1 indication · +1 synergie
Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.
Première publication publique
+21 références
Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.
+21 références — afficher les textes
Herz W et al: Acanthospermal A and Acanthospermum B, two new melampolides from Acanthospermum hispidum species. J Org Chem. 1975;40: 3486-91.
AjoutéeMathur SB et al: Isolation of triacontane, N-butyl eicosante & N-heptacosanol from Acanthospermum hispidum. Phytochemistry. 1976; 15: 2026.
AjoutéeSanon S et al: Antiplasmodial activity of alkaloid extracts from Pavetta crassipes (K. Schum) & Acanthospermum hispidum (DC), two plants used in Traditional medicine in Burkina. Faso. Parasitol Res. 2003; 90:314-7.
AjoutéeGANFON H et al, Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum Hispidum DC (Asteraceae), J of Ethnopharmacol, 11 :411-7, 2012.
AjoutéeTheresa IE et al: Two Flavones from Acanthospermum Hispidum DC & their Antibacterial Activity. Inter J of Organic Chem. 2011; 1(3):226-33.
AjoutéeArena ME et al: In vivo & in vitro Antibacterial activity of acanthospermal, B, a sesquiterpene lactone isolated from Acanthospermum hispidum. Phytother Research; 2011 25(4): 597–602.
AjoutéeCartagena E et al, Germacranolides & a new type of guaianolide from Acanthospermum hispidum. J Nat Prod 63: 1323-8.2000,
AjoutéeLemonica IP et al, Abortive & teratogenic effect of Acanthospermum hispidum DC & Cajanus cajan (L) Millps in pregnant rats J of Ethnopharm 1994; 43 :1:39-44.-Abstract: Extracts of Acanthospermum hispidum and Cajanus cajan have been used by Brazilian people in an attempt to produce abortion. In order to evaluate the possible abortive and/or teratogenic effect of these plant extracts, female Wistar rats were treated with the aqueous extract (infusion, proportion C. cajan and A. hispidum 1:1.3). Doses of 0, 150, 300 & 600 mg/kg were daily administered by gavage during the organogenic period. T…
AjoutéeEDEWOR IT et al, Effects Of Oral Administration Of Ethanolic Leaf Extract Of Acanthospermum Hispidum Dc On Carbon Tetrachloride Induced Acute Liver Injury In Rats, Biochem, 1(2), 2007-Abstract: -The effects of administering the ethanolic leaf extract of Acanthospermum hispidum dc on patients of hepatitis were studied on acute hepatitis induced by carbon tetrachloride (20% CCl4/olive oïl, 1.5 ml/kg, p.o) in rats. These effects were monitored by estimating the serum transaminases levels and the histopathological changes in the livers of experimental rats. The pretreatment of the animals with …
AjoutéeDeepa N et al: Antitumor Activity of Acanthospermum hispidum DC on Dalton Ascites Lymphoma in Mice. Natural Prod Sci. 2007; 13(3): 234-40.-Abstract: N. Deepa et al. (2007) investigated the antitumor activity of 50% aqueous ethanol extract of Acanthospermum hispidum DC against Dalton’s ascites Lymphoma in mice. The extracts were prepared by cold maceration with 50% aqueous ethanol and evaporated in vacuum to dry. (Yield: 50%aqueous ethanol -8.62% w/w). The extract was suspended in water with tween 20 and used for the study. The 50% aqueous ethanol extract (300 mg/kg p.o) was administered to …
AjoutéeADUE F et al, the effects of Acanthospermum hispidum extract on the antibacterial activity of Amoxicillin and Ciprofloxacin, Hygeia, J for Drugs & Med, 3(1), 58-63, 2011-Abstract: The effect of the sub-inhibitory concentrations of Acanthospermum hispidum extract on the activities of amoxicillin and ciprofloxacin was assessed by the Kirby-Bauer disc diffusion method. The extract demonstrated antibacterial activity against Staphylococcus aureus, Klebsiella pneumoniae, Bacillus subtilis, Salmonella typhi, Proteus vulgaris & Pseudomonas aeruginosa with MICs ranging between 11 and 53 mg/ml. A 5 …
AjoutéeHare-Krishna R et al, Preliminary Phytochemical investigation and Anthelmintic activity of Acanthospermum hispidum DC. Journal of Pharmaceut Sci & Technology. 2010; 2 (5): 217-21.
AjoutéeCOMPARITIVE STUDY OF HEPATOPROTECTIVE ACTIVITY OF ACANTHOSPERMUM HISPIDUM PLANT EXTRACT AND HERBAL NIOSOMAL SUSPENSION AGAINST ANTI-TUBERCULAR DRUG INDUCED HEPATOTOXICITY IN RATS, Asian J of Pharm & clinical Res, 8(5), 2015 -ABSTRACT: Compare the hepatoprotective activity of Acanthospermum hispidum ethanolic extract (AHEE) & herbal niosomal suspension (HNS) against hepatotoxicity. Methods: AHEE and HNS were investigated against hepatotoxicity produced by administering a combination of four Antitubercular drugs (ATDs) isoniazid (27 mg/kg), rifampin (40 mg/kg), Pyrazinamide (66 mg/kg), and et…
AjoutéeKPEMISSI M et al, Hepatoprotective & antioxidant effects of Acanthospermum hispidum (DC) leaves on carbon tetrachloride-induced acute liver damage in rat, https://www.researchgate.net/ Publication/293800399.
AjoutéeChakraborty AK et al, Phytopharmacological review on Acanthospermum Hispidum, J of Applied Pharm Sci 02 (01); 2012: 144-8-ABSTRACT: Acanthospermum Hispidum (Family: Asteraceae) is an annual plant which is native to tropical America. This plant is cited as a weed in cotton culture in Brazil, and it is also used as a medicinal plant. The leaves and flowering tops of the plant have antimicrobial activity. The ethanolic extract of leaves and flowering tops gives activities against wide range of pathogenic bacteria. Crushed herb is use in the form of the paste to treat the skin aliments and leaf…
AjoutéeEvani L et al: Acanthospermum hispidum DC (Asteraceae): perspectives for a phytotherapeutic Product. Rev. Bras. Farmacogn. 2008; 18.
AjoutéeNair AGR et al: Polyphenolic compounds from leaves of Acanthospermum hispidum. Fitoterapia. 1985; 56: 249-50.
AjoutéeFleischera TC et al: Antimicrobial activity of the leaves and flowering tops of Acanthospermum hispidum. Fitoterapia. 2003; 74: 130–2.-Abstract: The ethanolic extracts of the leaves and flowering tops of Acanthospermum hispidum showed varying degrees of activity against a wide range of pathogenic bacteria. The activity resided mostly in the polar fractions of the alcoholic extract, being only slight in the non-polar fractions. No activity was observed for the aqueous extract of the fresh plant material.
AjoutéeSummerfield A et al: Interleukin-2 dependent sélective activation of porcine γδ T lymphocytes by an extract from the leaves of Acanthospermum hispidum. Inter J of Immunopharmacol.1988; 20: 85-98.
AjoutéeSummerfield A et al, Antiviral activity of an extract from leaves of the tropical plant Acanthospermum hispidum. Antiviral Res. 1997;36: 55–62.
AjoutéeGOMATHI V et al, Preliminary Phytochemical and In-Vitro Antioxidant Activity of the Whole Plant of Acanthospermum Hispidum Dc, Inter J of Med & Pharm, 1(1), 2013-Abstract: A hispidum DC is a branched herb up to 60cm Tall. The stems of these plants are covered with bushy hairs and smaller glandular hairs. It is used for the treatment of jaundice, malaria, vomiting, cephalgias, headache, abdominal pain, convulsions, stomachache, constipation, eruptive fever, snake bite, epilepsy, blennorrhoea, Hepatobiliary disorders, malaria, microbial infection and viral infections. Acanthospermum hispidum …
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