Acanthus montanus (Zèb-dôwlis) : vertus médicinales en extraction alcoolique

Enitan A et al, Evaluation of different solvents for extraction of phytochemical constituents & antioxidant activities of the leaves of Acanthus montanus (Nees) T. Anderson, Lekovite Sirovine, 2021-Abstrac:Bear's breech or mountain thistle (Acanthus montanus (Nees) T. Anderson) is a shrub belonging to Acanthaceae family. It is widespread in Africa, Romania, Greece, & Eastern Mediterranean. African people engage its medicinal use for the management of urethral pain, endometritis, urogenital infections, urinary disease, aches & pains. Fresh leaves of AM were collected from Forestry Research I…

Patric-Iwuanyanwu K C et al, Prevention of carbon tetrachloride (CCl4)-induced liver damage in rats by Acanthus montanus. Asian J. of Biochem, 3(4), 213-20, 2008-Abstract: the hepatoprotective effects of aqueous & alcoholic extracts of stem & leaf of Acanthus montanus pre-treatment against carbon tetrachloride (CCl4,)-induced liver damage in wistar albino rats were investigated. The plant extracts were fed to the rats intragastricaly for 15 days prior to the administration of 0.5 mL CCl4 kg-1 body weight. Serum L-alanine aminotransferase (L-ALT), L-aspartate amino transferase (L-AST), lacta…

Adamu M et al, Anthelminthic Efficacy of Aqueous Extract of Acanthus Montanus Leaf Against Strongylid Nematodes of Small Ruminants, Afr J of Comp Alter Med, 7:4, 2010-Abstract: The anthelminthic efficacy of the crude aqueous extract of Acanthus montanus (Nees) T. Anders (Acanthaceae) against strongylid nematodes of small ruminants was investigated using the in-vitro egg hatch & larval growth inhibition assays. Faecal samples collected per rectum from sheep and goats were subjected to parasitological examination using the McMaster counting technique with a yield of 700 eggs per gram (E.P.G.)…

Asongalem EA et al, Anti-inflammatory, lack of central analgesia & antipyretic properties of Acanthus montanus (Ness) T. Anderson. J Ethnopharmacol. 2004;95:63–8-Abstract : Aqueous leaves extract of Acanthus montanus (Nees) T. Anderson (Acanthaceae) were tested for antiinflammatory, analgesic & antipyretic properties. This was done using standard methodologies following oral administration of the extract. The results showed that the extract significantly reduced the oedema induced by carrageenanwithin 30 min with 200 mg/kg being the most potent. On the analgesia front, acetic acid writhing …

Foyet HS et al, TOCOLYTIC EFFECT OF ACANTHUS MONTANUS IN RAT UTERUS, Pharmacologyonline 3 : 9-17, 2006-Abstract : The objective of this study was to investigate the tocolytic efficacy of A. montanus (Nees) T. Anderson (Acanthaceae) as a possible remedy for threatened abortion & dysmenorrhea. Aqueous & organic extracts & fractions of dried leaves prepared with different solvents (hexane, ethyl acetate & methanol) were tested in vitro for relaxant activity on rat uterus. Aqueous & organic extracts exhibited relaxant properties with the EC5values of 3.0 & 0.27 mg/ml respectively. Each extract…

Ogundajo A et al, Inhibition of α‐amylase & α‐glucosidase by Acanthus montanus leaf extracts. British J of Pharmaceuti Res, 9, 1–8.2016-Abstract:  The aim of this study was to determine the in-vitroanti-diabetic potentials of Acanthus montanus. This was done by assessing the inhibitory effect of both methanol & ethylacetate extracts of the plant on the activities of α-amylase & α-glucosidase. Study Design: The design included extraction of A. montanus leaves with methanol & ethanol & subsequent evaluation of the extracts for possible hypoglycemic effect. Place & Duration of Study: The leave…

Omekannaya B et al, Effects Of Methanol Extract Of Acanthus Montanus Leaves On Liver Function Induces Of Paracetamol Induced Male Wist Ar Albino Rats, Repository.mouau.edu.ng, 2023-Abstract:The study investigated the effects of methanol extract of Acanthus montanus leaves on liver function indices of paracetamol induced male albino rats. A total of 36 male rats & l 8 mice were used for the study. The rats were grouped into 9 groups of 4 animals each. Group I served as normal control, group 2 served as negative control, group 3 served as drug control, group 4: 200 mg/kg bwt of extract group,…

Ukwe CV et al, Hypoglycemic activity of leaves of Acanthus montanus T. Anderson (Acanthaceae) in rats. Inter J of Diabetes in Developing Countries, 31, 32, 2011-Abstract: Hypoglycemic activity of Acanthus montanus, used locally in Nigeria to “cure” diabetes, was evaluated. Phytochemical tests & acute toxicity tests were carried out on the methanolic extract. Using normoglycemic & alloxanized (alloxan monohydrate 70 mg/kg IV body weight) rats, pre-treatment was done with 400 mg/kg of the extract & glibenclamide 10 mg/kg as reference drug orally. Blood glucose levels of the rats were measured…

Matos P et al, A review of the ethnomedicinal uses, chemistry, & pharmacological properties of the genus Acanthus (Acanthaceae), J of Ethnopharmacol, 293 :115271, 2022-Abstract: The Acanthus genus belongs to the Acanthaceae family, & its species are distributed in all continents, mainly in tropical and subtropical regions. Several traditional applications are referred to, but few scientific studies validate them. Despite this, studies in animal models corroborate some of its uses in folk medicine, such as anticancer, antidiabetic, anti-inflammatory, & antinociceptive, which encourages the r…

Adeyemi OO et al, the relaxant activity of the methanolic extract of Acanthus montanus on intestinal smooth muscles. J Ethnopharmacol. 1999;68:169–73-Abstract: The effects of the methanolic extract of Acanthus montanus on different smooth muscle preparations have been investigated. The extract (6.25–100 μg/ml) produced a concentration-dependent relaxation & inhibition of the spontaneous contraction of the rabbit jejunum which was reversed by CaCl2 (0.1–1mM). This effect of the extract was not blocked by propranolol (3×10−7 M) but partially antagonised by phentolamine (10−6–3×10−6 M), procai…

Okoli CO et al, Acanthus montanus: An experimental evaluation of the antimicrobial, anti-inflammatory & immunological properties of a traditional remedy for furuncle, BMC COMP & ALTER MED, 8(1):27, 2008-Abstract: Acanthus montanus (Nees) T. Anderson (Acanthaceae) is a shrub widespread in Africa, the Balkans, Romania, Greece & Eastern Mediterranean. It is used in African traditional medicine for the treatment of urogenital infections, urethral pain, endometritis, urinary disease, cystitis, leucorrhoea, aches & pains. In southeastern Nigeria, the root is popular & acclaimed highly effective i…

Nana P et al, Maternal & developmental toxicity evaluation of Acanthus montanus leaves extract administered orally to Wistar pregnant rats during organogenesis, J of Ethnopharmacol, 116(2):228-33, 2008-Abstract: Acanthus montanus is a plant used in Cameroon to treat pains & threatened abortion. The aim of this study was to evaluate the influence of methanol/methylene chlorides leaves extract from AM on Wistar pregnant rats & identify the substance(s) essential for these actions. Dams were treated orally from days 6 to 15 of the pregnancy at the dose levels of 0, 250, 500 & 1000 mg/ (kg-day)…

Djami TAT et al, Subacute toxicity study of the aqueous extract from Acanthus montanus. Electronic J of Biol, 7, 11–15. 2011,

Igwe OU et al, Chemical Characterization & Investigation of the Bio- effects of the Leaves of Acanthus montanus (Acanthaceae) on Some Selected Microorganisms, Inter J of Chem Tech Res, 6(4):5554-61, 2014-Abstract: The leaves of Acanthus montanus are used in traditional herbal practices in South Eastern Nigeria & in some other parts of West Africa for the treatment of gonorrhoea, syphilis, wounds & boils. Other uses of AM in herbal medicine include the treatment of hypertension, cardiac dysfunctions, hepatitis & heart diseases. The chemical constituents of the ethanolic extract of the leaves…

Ikezu UJ et al, Structural elucidation & antimicrobial analysis of chloroform leaf extract of Acanthus montanus . IOSR J of Applied Chem, 7, 72–5, 2014,

Lowe A et al, Effect of processing on the biochemical contents of Acanthus montanus (Nees) T. Anderson (Acanthaceae) leaves, Food Sci Nutr, 6(2) :388-84, 2018-Abstract: The effect of processing on the biochemical contents of Acanthus montanus leaves was investigated. The moisture, crude protein, lipid, fiber, ash, & total carbohydrate contents of the raw vegetable were 59.15, 1.85, 2.32, 3.76, 2.04, & 34.65 g/100 g, respectively. The saponin, alkaloid, tannin, flavonoid, phenol, & anthocyanin contents of the raw vegetable were 5.35, 4.04, 1.10, 3.53, 2.87, & 1.27 g/100 g, respectively, whil…

Ngo Bun E et al, Validation of anticonvulsant & sedative activity of six medicinal plants, Epilepsy & Behavior, 14(3) :454-8, 2009-Abstract : Acanthus montanus, Alchornea laxiflora, Hyptis spicigera, Microglossa pyrifolia, Piliostigma reticulatum, & Voacanga africana were evaluated with respect to anticonvulsant & sedative activity in mice using animal models (maximal electroshock (MES), N-methyl-D-aspartate (NMDA), pentylenetetrazol (PTZ), isonicotinic hydrazide acid (INH), picrotoxin (PIC), and strychnine (STR)-induced convulsions or turning behavior & diazepam-induced sleep). A montanus …

Ojiako OA et al, Comparative Hypoglycemic Activities of Aqueous & Ethanolic Extracts of Four Medicinal Plants (Acanthus Montanus, Asystasia gangetica, Emilia coccinea & Hibiscus rosa sinensis) in Type I Diabetic Rats, J Comp Med Res. 2015; 4(3): 228-33-Abstract: The present study ascertained the capacities of crude aqueous & ethanolic leaf extracts of Acanthus Montanus, Asystasia gangetica, Emilia coccinea & Hibiscus rosa sinensis, as well as their Combinatorial formulations to ameliorate hyperglycemia in Type I diabetic rats. Methods: Hyperglycemia was induced by single intra-peritoneal in…