Agaricus blazei (Agaric) : vertus médicinales en extraction alcoolique

Agaricus blazei (Agaric, Champignon du soleil, Matsutake, Sun mushroom) — famille Agaricacées.

Synonymes scientifiques : Agaricus brasiliensis-Wasser, Didukh, A rufotegulis, var hadriaticus- L & N, Fungus subfrutescens-Ktze, Pasollota subfrutescens-(Ktze)-Kaujjman..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 17 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 118 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome gastrique, hépatique, pulmonaire (non-à-petite cellule), & lingual épithélial squameux

   Partie usitée : Mycelium.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Tung YC (2012)

     Excerpt SK-Hep-1 & HA22T/VGH cells are poorly differentiated human hepatocellular carcinoma cell lines with invasive and migratory abilities. Agaricus blazei (AB) is a mushroom with many biological effects & active ingredients, & the ethanolic extract of AB fermentation product (AB-pE) was demonstrated to inhibit the growth of hepatoma Hep3B & HepG2 cells in our previous study.

   • Selon Su ZY (2011)

     Excerpt Hepatocellular carcinoma is the most common type of liver cancer. Previously, it was reported that blazeispirol A (BA) is the most active antihepatoma compound in an ethanolic extract of Agaricus blazei fermentation product.

   • Selon Satoshi Ohno (2011)

     Excerpt Although many cancer patients use complementary and alternative medicine, including Agaricus blazei Murill (ABM), safety is not yet well understood. Adverse events were defined by subjective/objective symptoms & laboratory data

   • Excerpt according to the National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0 (NCI-CTCAE v3.0).

   • Selon da Silva de Souza AC (s.d.)

     Excerpt At least the following bioactivities can be considered as being supported by experimental evidence: antioxidant activity (in aging or disease), immunomodulation & cell signaling, anti-inflammatory activity, antiparasitic actions, antimicrobial activity, anticancer effects & tumor growth inhibiting effects, antimutagenic activity, hepatoprotection against chemical or viral infection & antidiabetic activity. The mushroom Agaricus blazei has evoked considerable scientific & practical interest in several fields, especially those linked to its medicinal properties.

   • Selon Hisamochi A (2013)

     Excerpt Their clinical courses from the start of CAM until the onset of DILI were observed unexpectedly, because they were under observation for stable malignant neoplasms: stage III malignant thymoma & stage IV lung cancer, respectively. Agaricus blazei Murill (ABM) is one of the most popular complementary alternative medicines (CAM).

2. 2

   Diabète mellitus de type II

   Partie usitée : Mycelium.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Firenzuoli, L (2008)

     Extrait Agaricus blazei Murill (ABM) popularly known as ‘Cogumelo do Sol’ in Brazil, or ‘Himematsutake’ in Japan, is a mushroom native to Brazil, & widely cultivated in Japan for its medicinal uses, so it is now considered as one of the most important edible & culinary-medicinal biotechnological species. It was traditionally used to treat many common diseases like atherosclerosis, hepatitis, hyperlipidemia, diabetes, dermatitis & cancer.

   • Selon Wei Q (2019)

     Extrait Agaricus blazei Murill (ABM), a medicinal mushroom, has beneficial effects on various human metabolic diseases. The objective of this research was to evaluate the antioxidant & antidiabetic properties of ABM extracts (ethanol extract & ethyl acetate extract).

   • Selon Hsu CH (2007)

     Extrait This study was done to determine whether the supplement of Agaricus blazei Murill extract improves insulin resistance in type 2 diabetes. The enrolled patients were randomly assigned to either receiving supplement of Agaricus blazei Murill (ABM) extract or placebo (cellulose) 1500 mg daily for 12 weeks.

   • Selon Vincent, M (2013)

     Extrait The present study aimed to test whether supplementation with Agaricus blazei Murill (ABM) extract could have an effect on diet-induced obesity in rats. Dietary supplement may potentially help to fight obesity and other metabolic disorders such as insulin-resistance a& low-grade inflammation.

   • Selon da Silva de Souza AC (s.d.)

     Extrait The mushroom Agaricus blazei has evoked considerable scientific & practical interest in several fields, especially those linked to its medicinal properties. At least the following bioactivities can be considered as being supported by experimental evidence: antioxidant activity (in aging or disease), immunomodulation & cell signaling, anti-inflammatory activity, antiparasitic actions, antimicrobial activity, anticancer effects & tumor growth inhibiting effects, antimutagenic activity, hepatoprotection against chemical or viral infection & antidiabetic activity.

3. 3

   Troubles hépatiques: cirrhose, hépatite, stéatose hépatique

   Partie usitée : Mycelium.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hisamochi A (2013)

     Extrait We experienced a case of a 60-year-old woman with severe hepatitis associated with extract of ABM & extract of Ganoderma lucidum, & a case of a 75-year-old man with drug-induced liver injury (DILI) associated with extract of ABM & fucoidan. The second point was that histological findings of the liver were very similar to autoimmune hepatitis (AIH).

   • Selon Hsu CH (s.d.)

     Extrait This 1-year open-label pilot study aims to observe whether Agaricus blazei Murill extract improves liver function in patients with hepatitis B. Four (4) patients with hepatitis B who met the criteria (1) aged between 20 & 65 years; (2) being Chinese; (3) having been a hepatic B carrier (HBAg (+)) for more than 3 years; (4) alanine amino-transferase > 100 IU/L; & (5) not taking lamivudine, alpha-interferon, or other drugs for hepatitis participated in the study with informed consent.

   • Selon Tung YC (2012)

     Extrait Agaricus blazei (AB) is a mushroom with many biological effects & active ingredients, & the ethanolic extract of AB fermentation product (AB-pE) was demonstrated to inhibit the growth of hepatoma Hep3B & HepG2 cells in our previous study. SK-Hep-1 & HA22T/VGH cells are poorly differentiated human hepatocellular carcinoma cell lines with invasive and migratory abilities.

   • Selon Su ZY (2011)

     Extrait Previously, it was reported that blazeispirol A (BA) is the most active antihepatoma compound in an ethanolic extract of Agaricus blazei fermentation product. Hepatocellular carcinoma is the most common type of liver cancer.

   • Selon Al-Dbass AM (2012)

     Extrait The findings indicate that the extract of AB can protect the liver against carbon tetrachloride induced oxidative damage in rats & is an efficient hepatoprotective & antioxidant agent against carbon tetrachloride induced liver injury. Also increase level of non-enzymatic antioxidant along with the decrease level in malondialdehyde was found in all experimental animals which were treated with Agaricus blazei Mushroom extract as compared with normal controls.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.