Aloe vera (Lalwé) : vertus médicinales en extraction alcoolique

Aloe vera (Lalwé, Aloès, Aloe) — famille Asphodeliacées.

Synonymes scientifiques : Aloe Barbadensis-Mill, A. Flava-Ros, A.elongata-Murr, A. perfoliata-L, var. Vera, A.vulgaris-Lam.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 15 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 59 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Ulcère du pied diabétique

   Partie usitée : FEUILLE (GEL).

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Mohan D (2014)

     Extrait Mohan D et al, an in vivo & in vitro investigation of the effect of Aloe vera gel ethanolic extract using animal model with diabetic foot ulcer, J Pharm Bio all. 2014, 6(3): 205–12-Aim: To examine the preventive effect of Aloe vera gel ethanolic extract using diabetic foot ulcer (DFUs) protocol in Wistar rats.

   • Selon Valentine UN (2018)

     Extrait This study was aimed at determining the phytochemical analysis & antibacterial activities of ethanol & methanol extract of Aloe vera leaves on bacteria isolated from diabetic foot ulcer patients. 150 swabs were obtained from diabetic foot ulcer patients in the hospital.

   • Selon Rajasekaran S (2006)

     Extrait The present study was designed to examine the potential Antihyperlipidaemic efficacy of the ethanolic extract from Aloe vera leaf gel in streptozotocin (STZ)-induced diabetic rats. Oral administration of A vera gel extract at a dose of 300 mg/kg bodyweight per day to STZ-induced diabetic rats for a period of 21 days resulted in a significant reduction in fasting blood glucose, hepatic transaminases (aspartate aminotransferase & alanine aminotransferase), plasma & tissue (liver and kidney) cholesterol, triglycerides, free fatty acids & phospholipids and a significant improvement in plasma insulin.

   • Selon Rajasekaran S (2005)

     Extrait This study was designed to evaluate the potential antioxidative activity of the ethanolic extract from Aloe vera leaf gel in the plasma & pancreas of streptozotocin (STZ)-induced diabetic rats. Oral administration of ethanolic extract at a concentration of 300 mg kg (-1) body weight for 21 days resulted in a significant reduction in fasting blood glucose, Thiobarbituric acid reactive substances, hydroperoxides & alpha-tocopherol & significant improvement in ascorbic acid, reduced glutathione & insulin in the plasma of diabetic rats.

   • Selon Rajasekaran S (2005)

     Extrait Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats.

2. 2

   Diabète mellitus de type II

   Partie usitée : FEUILLE (GEL). Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Mohan D (2014)

     Extrait Vera gel at a dose 30 mg/kg body weight per day to streptozotocin (STZ)-induced diabetic rats for a period of 9 days resulted in no change in blood glucose & plasma insulin. Vera gel ethanolic extract at a dose of 300 mg/kg body weight per day to diabetic rats for a period of 9 days resulted in a significant reduction in fasting blood glucose and a significant improvement in plasma insulin.

   • Selon Rajasekaran S (2006)

     Extrait The present study was designed to examine the potential Antihyperlipidaemic efficacy of the ethanolic extract from Aloe vera leaf gel in streptozotocin (STZ)-induced diabetic rats. Oral administration of A vera gel extract at a dose of 300 mg/kg bodyweight per day to STZ-induced diabetic rats for a period of 21 days resulted in a significant reduction in fasting blood glucose, hepatic transaminases (aspartate aminotransferase & alanine aminotransferase), plasma & tissue (liver and kidney) cholesterol, triglycerides, free fatty acids & phospholipids and a significant improvement in plasma insulin.

   • Selon Rajasekaran S (2005)

     Extrait This study was designed to evaluate the potential antioxidative activity of the ethanolic extract from Aloe vera leaf gel in the plasma & pancreas of streptozotocin (STZ)-induced diabetic rats. Oral administration of ethanolic extract at a concentration of 300 mg kg (-1) body weight for 21 days resulted in a significant reduction in fasting blood glucose, Thiobarbituric acid reactive substances, hydroperoxides & alpha-tocopherol & significant improvement in ascorbic acid, reduced glutathione & insulin in the plasma of diabetic rats.

   • Selon Rajasekaran S (2005)

     Extrait Antioxidant effect of Aloe vera gel extract in streptozotocin-induced diabetes in rats.

   • Selon Valentine UN (2018)

     Extrait This study was aimed at determining the phytochemical analysis & antibacterial activities of ethanol & methanol extract of Aloe vera leaves on bacteria isolated from diabetic foot ulcer patients. Solvents such as ethanol & methanol were used to extract the leaves of Aloe vera and screened for their phytochemical & antibacterial activities using standard methods.

3. 3

   Cancer : traitement adjuvant de l’adénocarcinome hépatique & pulmonaire, épithélial & utérin

   Partie usitée : FEUILLE (GEL).

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sudheer M (2011)

     Extrait The methanolic extract of Plumeria alba (Apocynaceae) & aqueous extract of Aloe vera (Liliaceae) were tested for their hepatoprotective activity against CCl 4 induced hepatotoxicity in adult male Wistar rats. Plumeria alba & Aloe vera, are described as a hepatoprotective in Ayurveda, the Indian system of medicine.

   • Selon Beya W (2012)

     Extrait Short term administration of A-vera extracts resulted in growth promotion, enhanced hepatic storage of metabolic substrates, increased ALP possibly in relation to bone growth & caused hypertrophy of the caecum of neonatal rats. When nursing mothers use Aloe vera, their babies are at risk of indirect exposure to Aloe vera via breast feeding or directly as health supplements.

   • Selon Karpagam T (2019)

     Extrait Vera were investigated using 3-(4,5-dimethylthiazole-2yl) -2,5-diphenyl tetrazolium Bromide assay on three human cancer cell lines HepG2 (liver cancer), HeLa (human cervical carcinoma cell line) & A549 (human lung adenocarcinoma epithelial cell line). In the present study, anticancer & cytotoxicity of Aloe vera ethanolic leaves extract was evaluated as the leaves of A.

   • Selon Jose J (2014)

     Extrait The present study was designed to determine the comparative anticancer activities of flavonoids isolated from Aloe vera, Mimosa pudica & Phyllanthus niruri against human breast carcinoma cell line (MCF-7) using MTT assay. Results : Flavonoids isolated from A vera, M pudica & P niruri showed cytotoxicity activity against human breast carcinoma cell line (MCF-7) & the inhibitory concentration at 50% growth (IC50) was found to be, M pudica (IC50= 35.52±0.50µg/ml), A vera (IC50= 54.97±0.36µg/ml) & P niruri (IC50= 84.88±0.87µg/ml).

   • Selon Madhavan S (2020)

     Extrait The control group of 700μg was compared with ethanolic extract of A vera & observed that it reduced the expression of TNF α (Tumor necrosis factor) & Interleukin 6 (IL-6). In this study we performed phytochemical screening of various Aloe vera extracts to compare its bioactive potential.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.