Annona cherimola (Chérimôl) : vertus médicinales en extraction alcoolique

Annona cherimola (Chérimôl, Chérimole, Cherimoya) — famille Annonacées.

Synonymes scientifiques : Annona acutifolia-Saff ex REF, A odorata-L, A pubescens-Salisb, A tripetala-Aiton.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 44 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Acarbose-like, Canagliflozine-like. Association synergique mentionnée : Glibenclamide, Acarbose.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon CALZADA F (2023)

     Extrait The antihyperglycemic activity of ethanolic extract from Annona cherimola Miller (EEAch) & its products were evaluated using in vivo & in silico assays. This research sorts in vivo & in silico pharmacological studies regarding the use of AC leaves as a source for the development of new potential antidiabetic agents for T2D control, such as flavonoids rutin & myricetin.

   • Selon Valdes M (2023)

     Extrait Both treatments were evaluated separately & in combination with the oral antidiabetic drugs (OADs) acarbose (Aca), metformin (Met), glibenclamide (Gli), & canagliflozin (Cana) in acute & subchronic assays. Ethanolic extract obtained from Annona cherimola Miller ( EEAc) & the flavonoid rutin (Rut) were evaluated in this study to determine their antihyperglycemic content, % HbA1c reduction, & antihyperlipidemic activities.

   • Selon Quílez A.M (2018)

     Extrait This review aims to achieve a comprehensive understanding of the research conducted so far on the local and traditional uses, pharmacological activities, mechanism of actions of active compounds, toxicity, & possible interactions with other drugs of the Annona species. Many investigations have been performed with extracts from the leaves, bark, fruit & seeds & have shown a wide range of pharmacological activities, such as antiprotozoal, antitumoural, antidiabetic, hepato-protective, anti-inflammatory & anxiolytic activities.

   • Selon Jamkhande PG (2017)

     Extrait Annona cherimola, commonly known as Custard apple has recently gained attention of researchers because of copious anticancer bioactive chemicals & nutrients. The crude extracts as well as isolated compounds from different plant parts exhibited pharmacological activities such as antidiabetic, antimicrobial, antidepressant, anxiolytic, antiviral, antitumor & cytoprotective.

   • Selon MARTINEZ-SOLIS J (2022)

     Extrait Annona cherimola Miller (Ac) is a plant used in Mexican traditional medicine for the treatment of diabetes. In this work, the tea infusion extracts obtained from 1.5 g of leaf powder from Ac collected in May (Ac-Ma), June (Ac-Jun), July (Ac-Jul), & August (AcAu) were evaluated on streptozocin-induced diabetic (STID) mice & for subchronic toxicity in STID & non-diabetic (ND) mice.

2. 2

   Cancer : traitement adjuvant de l’adénocarcinome gastrique

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Macuer-Guzman J (2019)

     Extrait cherimola seeds against the human stomach gastric adenocarcinoma (AGS) cell line & the normal human gastric epithelial cell line (GES-1). Annona cherimola is a tree belonging to the family Annonacea, whose fruit (cherimoya) is very desirable, but its seeds are considered waste.

   • Selon Jamkhande PG (2017)

     Extrait Annona cherimola, commonly known as Custard apple has recently gained attention of researchers because of copious anticancer bioactive chemicals & nutrients. Plants of the Annonaceae family have a long history of medicinal use in the treatment of several disease conditions such as epilepsy, cardiac diseases, pathogenic infections, hemorrhage, ulcer, cancer, liver disorders & other ailments.

   • Selon Ceramella J (2021)

     Extrait we investigated the antioxidant & anticancer properties on melanoma cells of three Annona cherimola leaves extracts (ethanolic, methanolic & aqueous). The ethanolic extract showed the most promising & interesting anticancer activity, mostly on the malignant A2058 melanoma cell line (I50-C= 5.6±0.8 ng/mL), without exerting cytotoxicity on the normal cells.

   • Selon Quílez A.M (2018)

     Extrait Many of the assays were carried out with the isolated acetogenins in different lines of tumour culture cells and were found effective at very low doses even in multidrug-resistant tumours, & hence constitute promising compounds in the treatment of different types of cancers. This review aims to achieve a comprehensive understanding of the research conducted so far on the local and traditional uses, pharmacological activities, mechanism of actions of active compounds, toxicity, & possible interactions with other drugs of the Annona species.

   • Selon Fuel M (2021)

     Extrait The antitumor effect of these extracts was evaluated in vitro with colorectal cancer (CRC) cell lines T84, HCT-15, SW480 & HT-29, as well as with cancer stem cells (CSCs). Moringa oleifera, Tropaeolum tuberosum & Annona cherimola are medicinal plants traditionally used in Ecuador.

3. 3

   Amibiase, diarrhée, dysenterie amibienne: Entomaeba histolytica & Giardia lamblia

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Calzada F (2017)

     Extrait Results: The in vitro antiprotozoal assay showed that kaempferol was the most potent antiamoebic & antigiardial compound with IC50 values of 7.9 μg/mL for Entamoeba histolytica & 8.7 μg/mL for Giardia lamblia. Annona cherimola Miller (Annonaceae) is a medicinal plant frequently recommended in Mexican traditional medicine for the treatment of gastrointestinal disorders such as diarrhea & dysentery.

   • Selon Bories C (1991)

     Extrait cherimolia (Annonaceae) seeds were tested for antiparasitic activity against E.

   • Selon Quílez A.M (2018)

     Extrait This review aims to achieve a comprehensive understanding of the research conducted so far on the local and traditional uses, pharmacological activities, mechanism of actions of active compounds, toxicity, & possible interactions with other drugs of the Annona species. Many investigations have been performed with extracts from the leaves, bark, fruit & seeds & have shown a wide range of pharmacological activities, such as antiprotozoal, antitumoural, antidiabetic, hepato-protective, anti-inflammatory & anxiolytic activities.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.