Lapotitjéri di la NatiLa pharmacie de la nature
← ActualitésFiche plante · Annona squamosa (Ponm-Kannèl)

← Actualités · Journal Actualités · English

Annona squamosa (Ponm-Kannèl) : vertus médicinales en extraction alcoolique

Annona squamosa (Ponm-Kannèl, Pomme-cannelle, Apple and Cinnamon) — famille Annonacées.

Synonymes scientifiques : Annona asiatica L., A asiatica Vahl, A cinerea Dunal, A distincta Raüsch., A forskohlii DC., Guanabanus squamosus M. Gómez, Xylopia glabra L.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 31 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 181 références scientifiques pour cette espèce (détail intégral dans l’application).

Indications thérapeutiques en extraction alcoolique :

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

  1. Cancer : chemoprevention du carcinome hépatique

    Partie usitée : Feuille.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon Vanitha V (2017)

      Extrait Vanitha V et al, Fabrication of nanoparticles using Annona squamosa leaf & assessment of its effect on liver (Hep G2) cancer cell line IOP Conf.

    • Selon MEHTA SD (2017)

      Extrait Traditionally, Annona Squamosa Linn has been used for treatment of cancer, diabetes, microbial infection, cardiac disease, jaundice and other liver related disorder. Hence the current work aims to explore the hepatoprotective of the Annona Squamosa (AS) seeds.

    • Selon VANITHA VKJ (2016)

      Extrait The role of phytonutrients presents in the active ethyl acetate fraction of the ethanolic leaf Annona squamosa in regulating the balance between cell proliferation and apoptosis via modulating the expression pattern of proliferation & apoptosis regulating genes in HepG2 cell line was analyzed by studying the mRNA levels of two genes Bcl2, & P53 involved in apoptotic pathway. The effect of ethyl acetate fraction of ethanolic leaf extract of Annona squamosa (EAELAS) was studied on a HepG2 cell line.

    • Selon Auteur (2008)

      Extrait Studies on the seeds of Annona squamosa yielded a novel lipoxygenase inhibitor fatty acid ester, (+) - annonlipoxy (1). The crude ethanolic extract of fruit pulp & seeds of A squamosa also exhibited lipoxygenase activity with 22.2 & 26.7% inhibition, while the pet.

    • Selon Ravaomanarivo LHR (2014)

      Extrait To evaluate the potential efficacy of seed extracts of Annona squamosa & Annona muricata used as natural insecticides to control adult and larvae of the vectors Aedes albopictus & Culex quinquefasciatus under laboratory conditions. Extracts of A muricata induced high mortality rate to both species of mosquito compared to extracts of A squamosa at all concentrations tested.

  2. Diabète mellitus de type II

    Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon Tomar RS (2014)

      Extrait extract at a dose of 350 mg/kg and 700 mg/kg & Glibenclamide at a dose of 5mg/kg for 28 days, after induction of diabetes by alloxan, caused significant reduction in blood serum glucose and serum lipid profiles like total cholesterol and triglycerides but significant increase in body weight & serum high density Lipoproteins (HDL) level in diabetic rats compared to untreated group. Diabetes mellitus is characterized by rise in blood sugar levels resulting from insulin dysfunction or insulin insufficiency.

    • Selon Gupta KR (2005)

      Extrait The ethanolic extract of Annona squamosa leaves was administered orally at different doses to normal as well as streptozotocin (STZ)-induced diabetic rats & alloxan-induced diabetic rabbits. The same dose of ethanolic extract reduced FBG by 26.8% & improved glucose tolerance by 38.5 and 40.6% at 1 and 2 h, respectively, during GTT in alloxan-induced diabetic rabbits.

    • Selon Saeed F (2017)

      Extrait Aim of this research work was to explore the anti-diabetic activity and acute toxicity of Annona squamosa leaves ethanolic extract in albino rats & mice respectively. squamosa was administered orally in 100mg, 200mg & 400mg doses in three different groups of diabetes- induced rats.

    • Selon MOUSSA AY (2024)

      Extrait The main reported biological activities for AS were cytotoxic, antidiabetic, antimicrobial, antiparasitic, antioxidant, antimalarial, Molluscidal, anthelmintic & insecticidal activities, & its chemical classes encompassed alkaloids, diterpenes, acetogenins, & cyclopeptides.

    • Selon Ponrasu T (2013)

      Extrait Annona squamosa is known for its antioxidant, antidiabetic & wound healing activity. We examined the efficacy of AS on the levels of enzymatic & nonenzymatic antioxidants during wound repair in normal & streptozotocin induced diabetic rats.

  3. Hépatite, cirrhose, stéatose hépatique

    Partie usitée : Semence.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon MEHTA SD (2017)

      Extrait Traditionally, Annona Squamosa Linn has been used for treatment of cancer, diabetes, microbial infection, cardiac disease, jaundice and other liver related disorder. Hence the current work aims to explore the hepatoprotective of the Annona Squamosa (AS) seeds.

    • Selon Auteur (2008)

      Extrait Studies on the seeds of Annona squamosa yielded a novel lipoxygenase inhibitor fatty acid ester, (+) - annonlipoxy (1). The crude ethanolic extract of fruit pulp & seeds of A squamosa also exhibited lipoxygenase activity with 22.2 & 26.7% inhibition, while the pet.

    • Selon VANITHA VKJ (2016)

      Extrait The role of phytonutrients presents in the active ethyl acetate fraction of the ethanolic leaf Annona squamosa in regulating the balance between cell proliferation and apoptosis via modulating the expression pattern of proliferation & apoptosis regulating genes in HepG2 cell line was analyzed by studying the mRNA levels of two genes Bcl2, & P53 involved in apoptotic pathway. The effect of ethyl acetate fraction of ethanolic leaf extract of Annona squamosa (EAELAS) was studied on a HepG2 cell line.

    • Selon Ravaomanarivo LHR (2014)

      Extrait To evaluate the potential efficacy of seed extracts of Annona squamosa & Annona muricata used as natural insecticides to control adult and larvae of the vectors Aedes albopictus & Culex quinquefasciatus under laboratory conditions. Extracts of A muricata induced high mortality rate to both species of mosquito compared to extracts of A squamosa at all concentrations tested.

    • Selon Rajeshkumar S (2015)

      Extrait Rajeshkumar S et al, PHYTOCHEMICAL SCREENING & HEPATOPROTECTIVE EFFICACY OF LEAVES EXTRACTS OF ANNONA SQUAMOSA AGAINST PARACETAMOL INDUCED LIVER TOXICITY IN RATS Inter Jl of Pharmacogn, 2015-DOI: 10.13040/IJPSR.0975-8232.IJP,.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.

Explorer la base (essai gratuit)

Évolution de cette fiche publique

Sous le CTA · journal des mises à jour

Contenu

+10 indications · −10 indications · +2 synergies · +13 références · −13 références

Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.

+10 indications−10 indications+2 synergies+13 références−13 références
+13 références — afficher les textes
Yang X et al. A review on the chemical constituents of Annona plants 17(3):186-9, back cover, 1992Yang X · 1992

Yang X et al. A review on the chemical constituents of Annona plants 17(3):186-9, back cover, 1992

Ajoutée
Hopp DC et al, Mono-THF ring annonaceous acetogenins from Annona squamosa. Phytochem. 1998; 47(5):803-9.Hopp DC · 1998

Hopp DC et al, Mono-THF ring annonaceous acetogenins from Annona squamosa. Phytochem. 1998; 47(5):803-9.

Ajoutée
Gupta RK et al, In vivo evaluation of anti-oxidant & anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models. Jl Ethnopharm 2008, 19; 118(1):21-5.Gupta RK · 2008

Gupta RK et al, In vivo evaluation of anti-oxidant & anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models. Jl Ethnopharm 2008, 19; 118(1):21-5.

Ajoutée
Hopp DC et al, Three new bioactive bis-adjacent THF-ring acetogenins from the bark of Annona squamosa. Bioorg Med Chem. 1998, 6(5):569-75.Hopp DC · 1998

Hopp DC et al, Three new bioactive bis-adjacent THF-ring acetogenins from the bark of Annona squamosa. Bioorg Med Chem. 1998, 6(5):569-75.

Ajoutée
Shirwaikar A et al, In vitro antioxidant studies of Annona squamosa Linn. leaves. Indian J Exp Biol. 2004, 42(8):803-7.Shirwaikar A · 2004

Shirwaikar A et al, In vitro antioxidant studies of Annona squamosa Linn. leaves. Indian J Exp Biol. 2004, 42(8):803-7.

Ajoutée
Yang X et al, Studies on the chemical constituents of Annona squamosa, Acta Pharmaceutica Sinica 1992-Yang X · 1992

Yang X et al, Studies on the chemical constituents of Annona squamosa, Acta Pharmaceutica Sinica 1992-

Ajoutée
Chen Y et al, Monotetrahydrofuran annonaceous acetogenins from the seeds of Annona squamosa. Phytochem Letters 2012, 5 (1), 33-6-Abstract: Three new Monotetrahydrofuran annonaceous acetogenins, AnnosqChen Y · 2012

Chen Y et al, Monotetrahydrofuran annonaceous acetogenins from the seeds of Annona squamosa. Phytochem Letters 2012, 5 (1), 33-6-Abstract: Three new Monotetrahydrofuran annonaceous acetogenins, Annosquamosin A–C (1–3) were isolated from the 95% EtOH extract of Annona squamosa seeds, in addition to the known compounds, solamin, annotemoyin-1, uvariamicin-II, uvariamicin-III. Their structures were elucidated by spectroscopic analysis & the relative configurations of bearing tetrahydrofuran rings were established by comparing NMR data with model compounds,

Ajoutée
Panda S et al, Antidiabetic & antioxidative effects of Annona squamosa leaves are possibly mediated through quercetin-3-O-glucoside. Biofactors. 2007; 31(3-4):201-10.Panda S · 2007

Panda S et al, Antidiabetic & antioxidative effects of Annona squamosa leaves are possibly mediated through quercetin-3-O-glucoside. Biofactors. 2007; 31(3-4):201-10.

Ajoutée
Nagaraj B, Evaluation of Annona Squamosa Leaf Extract for its Adaptogenic & Antidepressant Activity, Thesis, Bangalore, 560041.-Abstract: Perusal of the literature survey indicates that there are no lAuteur inconnu

Nagaraj B, Evaluation of Annona Squamosa Leaf Extract for its Adaptogenic & Antidepressant Activity, Thesis, Bangalore, 560041.-Abstract: Perusal of the literature survey indicates that there are no literatures or studies were done on the Adaptogenic & Antidepressant activity of leaf extract of Annona squamosa. The uses of herbal drugs are being more popular. This study is designed to evaluate the Adaptogenic & Antidepressant activity of leaf extract of A squamosa.

Ajoutée
Chen Y et al. Anti-tumor activity of Annona squamosa seeds extract containing annonaceous acetogenin compounds. Jl of Ethnopharm. 2012; 142:462–6-Abstract: Three new bis-tetrahydrofuran annonaceous acChen Y · 2012

Chen Y et al. Anti-tumor activity of Annona squamosa seeds extract containing annonaceous acetogenin compounds. Jl of Ethnopharm. 2012; 142:462–6-Abstract: Three new bis-tetrahydrofuran annonaceous acetogenins (1–3) were isolated from a 95% EtOH extract of Annona squamosa seeds. Four known annonaceous acetogenins, uvarigrandin A (4), bullatacin (5), squamostatin-A (6), and squamostatin-D (7), were also isolated. Their structures were elucidated by spectroscopic analyses, and the absolute configurations of the carbinol centers of 1–3 were defined by application of the Mosher method. These co…

Ajoutée
Gupta RK et al. In vivo evaluation of anti-oxidant & anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models. Jl of Ethnopharm 2008; 118(1):21–5.Gupta RK · 2008

Gupta RK et al. In vivo evaluation of anti-oxidant & anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models. Jl of Ethnopharm 2008; 118(1):21–5.

Ajoutée
Panda S et al, Annona squamosa seed extract in the regulation of hyperthyroidism & d lipid-peroxidation in mice: possible involvement of quercetin. Phytomed. 2007; 14(12):799-805.-Abstract: Annona squPanda S · 2007

Panda S et al, Annona squamosa seed extract in the regulation of hyperthyroidism & d lipid-peroxidation in mice: possible involvement of quercetin. Phytomed. 2007; 14(12):799-805.-Abstract: Annona squamosa (Custard apple) seeds are generally thrown away as waste materials. The extract of these seeds was evaluated for its possible ameliorative effect in the regulation of hyperthyroidism in mouse model. Serum triiodothyronine (T (3)), thyroxine (T (4)) concentrations, hepatic glucose-6-phospatase (G-6-Pase) & 5'-mono-deiodinase (5'DI) activity were considered as the end parameters of thyroid …

Ajoutée
Shirwaikar A et al, Antidiabetic activity of aqueous leaf extract of Annona squamosa in streptozotocin–nicotinamide type 2 diabetic rats, Jl of Ethnopharmacol, 91 (1): 171-5, 2004-doi: 10.1016/j.jep.2Shirwaikar A · 2004

Shirwaikar A et al, Antidiabetic activity of aqueous leaf extract of Annona squamosa in streptozotocin–nicotinamide type 2 diabetic rats, Jl of Ethnopharmacol, 91 (1): 171-5, 2004-doi: 10.1016/j.jep.2003.12.017,

Ajoutée
Yang X et al. A review on the chemical constituents of Annona plants 17(3):186-9, back cover, 1992Yang X · 1992

Yang X et al. A review on the chemical constituents of Annona plants 17(3):186-9, back cover, 1992

Retirée
Panda S et al, Antidiabetic & antioxidative effects of Annona squamosa leaves are possibly mediated through quercetin-3-O-glucoside. Biofactors. 2007; 31(3-4):201-10.Panda S · 2007

Panda S et al, Antidiabetic & antioxidative effects of Annona squamosa leaves are possibly mediated through quercetin-3-O-glucoside. Biofactors. 2007; 31(3-4):201-10.

Retirée
Chen Y et al. Anti-tumor activity of Annona squamosa seeds extract containing annonaceous acetogenin compounds. Jl of Ethnopharm. 2012; 142:462–6-Abstract: Three new bis-tetrahydrofuran annonaceous acChen Y · 2012

Chen Y et al. Anti-tumor activity of Annona squamosa seeds extract containing annonaceous acetogenin compounds. Jl of Ethnopharm. 2012; 142:462–6-Abstract: Three new bis-tetrahydrofuran annonaceous acetogenins (1–3) were isolated from a 95% EtOH extract of Annona squamosa seeds. Four known annonaceous acetogenins, uvarigrandin A (4), bullatacin (5), squamostatin-A (6), and squamostatin-D (7), were also isolated. Their structures were elucidated by spectroscopic analyses, and the absolute configurations of the carbinol centers of 1–3 were defined by application of the Mosher method. These co…

Retirée
Nagaraj B, Evaluation of Annona Squamosa Leaf Extract for its Adaptogenic & Antidepressant Activity, Thesis, Bangalore, 560041.-Abstract: Perusal of the literature survey indicates that there are no lAuteur inconnu

Nagaraj B, Evaluation of Annona Squamosa Leaf Extract for its Adaptogenic & Antidepressant Activity, Thesis, Bangalore, 560041.-Abstract: Perusal of the literature survey indicates that there are no literatures or studies were done on the Adaptogenic & Antidepressant activity of leaf extract of Annona squamosa. The uses of herbal drugs are being more popular. This study is designed to evaluate the Adaptogenic & Antidepressant activity of leaf extract of A squamosa.

Retirée
Gupta RK et al. In vivo evaluation of anti-oxidant & anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models. Jl of Ethnopharm 2008; 118(1):21–5.Gupta RK · 2008

Gupta RK et al. In vivo evaluation of anti-oxidant & anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models. Jl of Ethnopharm 2008; 118(1):21–5.

Retirée
Hopp DC et al, Mono-THF ring annonaceous acetogenins from Annona squamosa. Phytochem. 1998; 47(5):803-9.Hopp DC · 1998

Hopp DC et al, Mono-THF ring annonaceous acetogenins from Annona squamosa. Phytochem. 1998; 47(5):803-9.

Retirée
Gupta RK et al, In vivo evaluation of anti-oxidant & anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models. Jl Ethnopharm 2008, 19; 118(1):21-5.Gupta RK · 2008

Gupta RK et al, In vivo evaluation of anti-oxidant & anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models. Jl Ethnopharm 2008, 19; 118(1):21-5.

Retirée
Hopp DC et al, Three new bioactive bis-adjacent THF-ring acetogenins from the bark of Annona squamosa. Bioorg Med Chem. 1998, 6(5):569-75.Hopp DC · 1998

Hopp DC et al, Three new bioactive bis-adjacent THF-ring acetogenins from the bark of Annona squamosa. Bioorg Med Chem. 1998, 6(5):569-75.

Retirée
Shirwaikar A et al, In vitro antioxidant studies of Annona squamosa Linn. leaves. Indian J Exp Biol. 2004, 42(8):803-7.Shirwaikar A · 2004

Shirwaikar A et al, In vitro antioxidant studies of Annona squamosa Linn. leaves. Indian J Exp Biol. 2004, 42(8):803-7.

Retirée
Yang X et al, Studies on the chemical constituents of Annona squamosa, Acta Pharmaceutica Sinica 1992-Yang X · 1992

Yang X et al, Studies on the chemical constituents of Annona squamosa, Acta Pharmaceutica Sinica 1992-

Retirée
Shirwaikar A et al, Antidiabetic activity of aqueous leaf extract of Annona squamosa in streptozotocin–nicotinamide type 2 diabetic rats, Jl of Ethnopharmacol, 91 (1): 171-5, 2004-doi: 10.1016/j.jep.2Shirwaikar A · 2004

Shirwaikar A et al, Antidiabetic activity of aqueous leaf extract of Annona squamosa in streptozotocin–nicotinamide type 2 diabetic rats, Jl of Ethnopharmacol, 91 (1): 171-5, 2004-doi: 10.1016/j.jep.2003.12.017,

Retirée
Chen Y et al, Monotetrahydrofuran annonaceous acetogenins from the seeds of Annona squamosa. Phytochem Letters 2012, 5 (1), 33-6-Abstract: Three new Monotetrahydrofuran annonaceous acetogenins, AnnosqChen Y · 2012

Chen Y et al, Monotetrahydrofuran annonaceous acetogenins from the seeds of Annona squamosa. Phytochem Letters 2012, 5 (1), 33-6-Abstract: Three new Monotetrahydrofuran annonaceous acetogenins, Annosquamosin A–C (1–3) were isolated from the 95% EtOH extract of Annona squamosa seeds, in addition to the known compounds, solamin, annotemoyin-1, uvariamicin-II, uvariamicin-III. Their structures were elucidated by spectroscopic analysis & the relative configurations of bearing tetrahydrofuran rings were established by comparing NMR data with model compounds,

Retirée
Panda S et al, Annona squamosa seed extract in the regulation of hyperthyroidism & d lipid-peroxidation in mice: possible involvement of quercetin. Phytomed. 2007; 14(12):799-805.-Abstract: Annona squPanda S · 2007

Panda S et al, Annona squamosa seed extract in the regulation of hyperthyroidism & d lipid-peroxidation in mice: possible involvement of quercetin. Phytomed. 2007; 14(12):799-805.-Abstract: Annona squamosa (Custard apple) seeds are generally thrown away as waste materials. The extract of these seeds was evaluated for its possible ameliorative effect in the regulation of hyperthyroidism in mouse model. Serum triiodothyronine (T (3)), thyroxine (T (4)) concentrations, hepatic glucose-6-phospatase (G-6-Pase) & 5'-mono-deiodinase (5'DI) activity were considered as the end parameters of thyroid …

Retirée

Par Emmanuel Nossin · ethnopharmacologue

Contenu

Première publication publique

Nouvelle plantetop 3 · nb refs

Par Emmanuel Nossin · ethnopharmacologue