Areca catechu (Arékié) : vertus médicinales en extraction alcoolique
Areca catechu (Arékié, Arequier) — famille Arecacées.
Synonymes scientifiques : Areca catechu-Burm.f, A macrocarpa-C ex M.
Sources externes reconnues associées à cette monographie : Pharmacopée française.
Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 24 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 98 références scientifiques pour cette espèce (détail intégral dans l’application).
Indications thérapeutiques en extraction alcoolique :
Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).
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Diabète mellitus de type II
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Sahane RS (2013)
Extrait The present study was done to evaluate the ethanolic extract of Areca catechu leaves for antidiabetic activity in Sprague Dawley rats. Diabetes mellitus was induced in rats by High fat diet, high fat emulsion & intraperitoneal injection of Streptozotocin (STZ, 35mg/kg body weight).
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Selon Song F (2022)
Extrait This study focused on the flavonoid compounds of arecanut & their in vitro bioactivities, including antioxidant activities and inhibitory potential towards enzymes involved in the treatment of hyperglycemia & hypertension. Furthermore, ultra-high-performance liquid chromatography coupled with mass spectrometry(UHPLC–MS/MS) was utilized to characterize the flavonoidcompositions in extracts of areca nut.
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Selon Mondal S (2012)
Extrait Diabetes mellitus was induced in rats by single intraperitoneal injection of streptozotocin (STZ, 50 mg/kg body weight). Areca catechu commonly known as Areca nut in English, is a perennial tree occurring throughout the Indian subcontinent & used traditionally for several medicinal purposes.
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Selon Ghate R (2014)
Extrait catechu flowers were administrated orally at the dose of 500 mg/kg for hypoglycemic effect in alloxan induced diabetic rats for 21 d. catechu flowers have shown a significant antidiabetic efficacy in alloxan induced diabetic rats.
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Selon Balkrishna A (2023)
Extrait Some common herbal remedies, including Foeniculum vulgare, Tinospora cordifolia, Asparagus racemosus, Ocimum tenuiflorum, Areca catechu, & Lepidium meyenii, have been highly regarded sources that have the benefits of lowering PCOS as well as having hypoglycemic & antiobesity effects. PCOS is linked to obesity, insulin resistance, & increased amounts of androgens, or male hormones.
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Selon Sahane RS (2013)
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Cancer : traitement adjuvant du carcinome mammaire & oral squameux
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon Sari ML (2017)
Extrait This study was undertaken to assess the anticancer potential of areca nut extract on human squamous carcinoma (HSC)-3, HSC-2 & human keratinocyte (HaCat) cancer cell lines, and to elucidate the mechanism of its action. Areca (betel, Areca catechu) nuts have been reported to show high contents of phenolic and flavonoid compounds with associated antioxidant activity.
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Selon Lakshmi T (2017)
Extrait catechu seed (ACS) against SCC-25 human oral squamous carcinoma cell line. Conclusion:The ethanol seed extracts of AC was found to be cytotoxic at lower concentrations & induced apoptosis in human oral squamous carcinoma SCC-25 cells.
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Selon Meiyanto E (2003)
Extrait This research therefore addressed to examine the inhibitory effect of Areca catechu seed ethanolic extract (EP) on proliferating breast cancer cells, MCF-7. These results conclude that Areca catechu seed ethanolic extract (EP) possesses antiproliferative effect through growth inhibition & apoptosis induction.
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Selon BHAT JG (2023)
Extrait With this information, we formulated a polyherbal preparation chiefly containing these two plant products & evaluated its anticancer efficacy on the specific cancer cell line. It was screened for its anticancer properties against A549 cancer cell lines.
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Selon Meiyanto E (2009)
Extrait Previous study on cytotoxic activity of Areca catechu L. on human colon cancer WiDr cells showed that the IC50 values of AC ethanolic extract (AE) & AC chloroform fraction (ACF) were 124 µg/mL & 119 µg/mL respectively.
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Selon Sari ML (2017)
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HTA, oedème
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon BHANDARE AM (2010)
Extrait The hydroalcoholic extract of Areca catechu L. Altogether, these results suggest that the hydroalcoholic extract of AC could be considered as a potential analgesic, anti-inflammatory & antioxidant agent.
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Selon Anthikat RRN (2012)
Extrait Objective: To explore the Anti-inflammatory activity of aqueous extract of A catechu L in carrageenan, dextran & formalin induced inflammation models in Swiss albino mice, by injection into the interdigital area, through the subplantar region of the paw. Results: The present investigation provides proof for the effectiveness of treatment as an anti-inflammatory and antioxidant agent.
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Selon SARTINA A (2022)
Extrait The objective of this review is to collect information about the Arecaceae family as anti-OA agents, with the main study focusing on the primary & secondary metabolites of plants of the Arecaceae family, i.e., sugar palm (Arenga pinnata), nipa palm (Nypa fruticans), palmyra palm (Borassus flabellifer), date palm (Phoenix dactylifera), & betel nut (Areca catechu) have potential as anti-OA agents. The Aceraceae’s metabolites that show anti-inflammatory & chondroprotective effects are galactomannan, fatty acids (linoleic and linolenic acids), flavonoids (quercetin, luteolin, isorhamnetin), phenolics (coumaric acid, ferulic acid), polyphenols (epicatechin), & steroids (stigmasterol, campesterol, spirostane).
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Selon Lee KP (2014)
Extrait The anti-inflammatory effect of Indonesian Areca catechu leaf extract in vitro & in vivo.
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Selon Sharafudheen J (2015)
Extrait Sharafudheen J et al, Anti-inflammatory & antinociceptive activities of areca nut water extract.
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Selon BHANDARE AM (2010)
D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.
Évolution de cette fiche publique
Sous le CTA · journal des mises à jour
+3 indications · ~7 indications corrigées · +1 synergie · +8 références · ~5 références corrigées
Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes des références ajoutées, corrigées ou retirées sont ci-dessous.
+8 références — afficher les textes
Rahmi F et al, Apoptosis effect of Areca catechu L. chloroform fraction on T47D cells, Proceeding Faculty of Pharma UGM, 75-82.2008-
AjoutéeBalkrishna A et al, Incredible Combination of Lifestyle Modification & Herbal Remedies for Polycystic Ovarian Syndrome Management, Evid Based Comp & Alter Med, 3705508, 2023-Abstract: A relatively frequent endocrine-metabolic illness called polycystic ovarian syndrome (PCOS) is characterized by polycystic ovaries, persistent anovulation, & hyperandrogenism, which cause symptoms such as irregular menstruation, infertility, & hirsutism. PCOS is linked to obesity, insulin resistance, & increased amounts of androgens, or male hormones. The sedentary lifestyle, dietary fluctuations, inactivity, …
AjoutéeBHAT JG et al, ANTIICANCER PROPERTY OF AN AYURVEDIC POLYHERBAL PREPARATION CHIEFLY CONTAINING ARECA NUT & BETEL LEAF, Int Jl of Res in A2yurveda & Pharm, 14(1):13-6, 2023-Abstract: Areca nut, the nut of the areca palm (Areca catechu L.) & the leaf of betel vine (Piper betle L.) are the two inevitable ingredients of the common chewing mixture popularly known as betel quid. Both traditional & modern research findings proved that these two plant products have many medicinal values, including anticancer properties. With this information, we formulated a polyherbal preparation chiefly containing…
AjoutéeHandayani S et al, Areca (Areca catechu L.) Seeds Ethanolic Extract & Its Chloroform Fraction Induce Apoptosis & Decrease COX-2 Expression on WiDr Cells, Proceeding, Faculty of Pharmacy UGM, 67-74.2008-
AjoutéeJaiswal P et al, Molluscicidal activity of Carica papaya & Areca catechu against the freshwater snail Lymnaea acuminata, Vèt Parasitol, 152(3-4):264-70.2008-abstract: The molluscicidal activity of seed & lyophilized latex powder of Carica papaya & seed powder of Areca catechu against the vector snail Lymnaea acuminata was studied. The toxicity of these plant products was time & dose dependent. The toxicity of CP lyophilized latex powder (LC (50) at 96 h: 8.38 mg/l) was more pronounced than that of AC seed powder (LC (50) at 96 h: 12.32 mg/l) & CP seed powder (LC (50) at 96 h: 61.56 mg/l). E…
AjoutéeMeiyanto E et al, Areca (Areca catechu L.) Seeds Ethanolic Extract & Its Chloroform Fraction Increase Apoptotic Effect of Doxorubicin on Human Colon Cancer Cells,Resaerch-gate, 2009-Abstract: Previous study on cytotoxic activity of Areca catechu L. on human colon cancer WiDr cells showed that the IC50 values of AC ethanolic extract (AE) & AC chloroform fraction (ACF) were 124 µg/mL & 119 µg/mL respectively. The aim of this research is to examine the effect of combination between AE & ACF with doxorubicin, a widely used chemotherapeutic agent & whether these combinations induce apoptosis on …
AjoutéeSARTINA A et al, Potential metabolites of Arecaceae family for the natural anti-osteoarthritis medicine: A review, Heliyon, 8(12): e12039, 2022-Abstract: Osteoarthritis (OA) is a chronic inflammatory disorder of the joints caused by fluid and cartilage matrix component reduction. This disease results in symptoms of pain, deformity, and limitation of movement. In general, OA is treated with anti-inflammatory drugs & chondro-protection compounds, includes natural nutraceutical ingredients, which are expected to be effective & have minimal side effects. Arecaceae plants are widely spread world…
AjoutéeHandayani S et al, The Safety of Areca Seed Ethanolic Extract as Potential Chemopreventive Agent is Proven by Acute Toxicity Test, Indonesian Jl of Cancer Chem, 3:1, 2012-Abstract: Areca (Areca catechu L.) seeds ethanolic extract (AE) exhibits antiproliferative activity & induces apoptosis on T47D & MCF-7 cells. This study aimed to verify AE safety using acute toxicity test to support its development as chemopreventive agent. Male Sprague Dawley Rat (Rattus norvegicus) age 8 weeks divided into five groups, one group of control treated with 0.5% CMC-Na only & four groups for treatment. Singl…
AjoutéeAhn BY, Free Radical Scavenging Effect of Ethanol Extract from Areca catechu, J. Korean Soc. Appl. Biol. Chem. 52(1), 92-5, 2009.-Abstract: The medicinal plants used in the present study were purchased from the Korea Medicine Herbs Association (Korea). The plants were ground into 80 mesh & stored at 4°C for use as specimen for extraction. DPPH, L-ascorbic acid, BHA, & BHT were purchased from Sigma Chemical Co. (St. Louis, MO). Approximately 10 g of each medicinal plant was separately put into 100 mL of 100% ethanol, extracted repeatedly at 37°C two times for 12 h each time. The solution was…
CorrigéeMeiyanto et al, Ethanolic extract of Areca catechu L. seeds inhibit proliferation & induce apoptosis on MCF-7 cells, Indonesia J Pharm, (19)1 :12-8, 2003-Abstract: Areca catechu seed contains antioxidant substances, supposed to have anticancer property. This research therefore addressed to examine the inhibitory effect of Areca catechu seed ethanolic extract (EP) on proliferating breast cancer cells, MCF-7. Areca catechu seed ethanolic extract (EP) standardization was done according to the standard of BPOM. Areca catechu seed powder extraction was done using ethanol 96%. Cytotoxic assay – t…
CorrigéeZhang WM et al, Antioxidant activities of extracts from areca (Areca catechu L) flower, husk & seed, African Jl of Biotechnol, 8 (16) :2010-Abstract: The antioxidant activities of areca (Areca catectu L.) flower, husk & seed extracts were evaluated using 3 complementary in vitro assays, inhibition of DPPH (1,1-diphenyl-2- picrylhydrazyl) radicals, inhibition of hydroxyl radicals & reducing power system. The EC50 values were calculated for all the methods in order to evaluate the antioxidant efficiency of areca extracts. The phenol a&flavonoid contents were also analyzed. Areca seed has the …
CorrigéeVeerakumari L. In vitro studies on the effect of some anthelmintics on Cotylophoron cotylophorum (Fischoeder, 1901) (Digenea: Paramphistomidae) - A structural & biochemical analysis. 1996; Ph.D. Thesis submitted to the Univ of Madras, Chennai.
CorrigéeChu NS, Neurological aspects of Areca & betel chewing, Addiction Biol, 2006.-Abstract: Betel quid chewing has been claimed to produce a sense of well‐being, euphoria, warm sensation of the body, sweating, salivation, palpitation, heightened alertness and increased capacity to work. These effects suggest that betel quid chewing affects predominantly the central and autonomic nervous systems. Several studies have been conducted to elucidate the central and autonomic effects of betel quid chewing. The results are: (1) betel quid chewing increased the heart rate with onset within 2 minutes, max…
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