Averrhoa carambola (Karanbôl) : vertus médicinales en extraction alcoolique

Averrhoa carambola (Karanbôl, carambole, carambola) — famille Oxalidacées.

Synonymes scientifiques : Averrhoa acutangula-Stokes, Sarcotheca Philippica-(Vilar)-Hallier f..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 21 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 78 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer traitement adjuvant du carcinome hépatique

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Luan F (2012)

     Extrait Pharmacological studies have revealed that crude extracts or monomeric compounds from AC exhibit multiple bioactivities, such as anti-oxidant, anti-hyperglycemic, anti-obesity, anti-hyperlipidemic, anti-tumor, anti-inflammatory, hepatoprotective, cardioprotective, anti-hypertensive, neuroprotective, & others. Averrhoa carambola is an edible fruit that is extensively cultivated in southern China, Southeast Asia, India, and northern South America.

   • Selon Singh R (2014)

     Extrait This study suggests the prophylactic role of AC against hepatocellular carcinoma in mice; therefore, it could be employed for the further screening as a good chemopreventive natural supplement against cancer. The current study was designed to evaluate the prophylactic role of the fruit of Averrhoa carambola(star fruit or Kamrak) on diethylnitrosamine- (DENA-) induced (15 mg/kg b.wt.; single i.p.

   • Selon Sharma J (2014)

     Extrait In the present study, the ability of Averrhoa carambola fruit extract to reduce Diethylnitrosamine/Carbon tetrachloride (DENA/CCl4) induced oxidative stress & hepato-carcinogenesis in Swiss albino mice was investigated. Therefore, the results from the present study demonstrate that the fruit extract of AC has the potential to reduce the liver cancer by alleviating the oxidative stress during chemical induced carcinogenesis in mammals.

   • Selon Chin JH (2010)

     Extrait All animals were sacrificed at day-15 & various organs such as liver, kidney & heart were removed.

   • Selon Zhang JW (2007)

     Extrait To examine the inhibitory effects of star fruit (Averrhoa carambola) juice towards seven major cytochrome P450 (CYP) isoforms & NADPH-cytochrome P450 reductase (CPR). Methods: The inhibitory effects of star fruit juice (0.5 to 5%, v/v) against the activities of seven CYP isoforms including CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP3A4 & CPR were examined in human liver microsomes.

2. 2

   Cancer : traitement adjuvant du carcinome hépatique

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sharma J (2014)

     Extrait In the present study, the ability of Averrhoa carambola fruit extract to reduce Diethylnitrosamine/Carbon tetrachloride (DENA/CCl4) induced oxidative stress & hepato-carcinogenesis in Swiss albino mice was investigated. Therefore, the results from the present study demonstrate that the fruit extract of AC has the potential to reduce the liver cancer by alleviating the oxidative stress during chemical induced carcinogenesis in mammals.

   • Selon Singh R (2014)

     Extrait This study suggests the prophylactic role of AC against hepatocellular carcinoma in mice; therefore, it could be employed for the further screening as a good chemopreventive natural supplement against cancer. The current study was designed to evaluate the prophylactic role of the fruit of Averrhoa carambola(star fruit or Kamrak) on diethylnitrosamine- (DENA-) induced (15 mg/kg b.wt.; single i.p.

   • Selon Luan F (2012)

     Extrait Pharmacological studies have revealed that crude extracts or monomeric compounds from AC exhibit multiple bioactivities, such as anti-oxidant, anti-hyperglycemic, anti-obesity, anti-hyperlipidemic, anti-tumor, anti-inflammatory, hepatoprotective, cardioprotective, anti-hypertensive, neuroprotective, & others. Averrhoa carambola is an edible fruit that is extensively cultivated in southern China, Southeast Asia, India, and northern South America.

   • Selon Chin JH (2010)

     Extrait All animals were sacrificed at day-15 & various organs such as liver, kidney & heart were removed.

   • Selon Zhang JW (2007)

     Extrait To examine the inhibitory effects of star fruit (Averrhoa carambola) juice towards seven major cytochrome P450 (CYP) isoforms & NADPH-cytochrome P450 reductase (CPR). Methods: The inhibitory effects of star fruit juice (0.5 to 5%, v/v) against the activities of seven CYP isoforms including CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2D6, CYP2E1, CYP3A4 & CPR were examined in human liver microsomes.

3. 3

   Diabète mellitus de type II

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shahreen S (2012)

     Extrait Averrhoa carambola L. The standard antihyperglycemic drug, glibenclamide, caused a 57.3% reduction in serum glucose levels versus control.

   • Selon Daud N (2013)

     Extrait An ethanolic extract of leaves & fruits of Averrhoa bilimbi (250 mg/kg) was orally administered to normal & diabetic male Wistar rats for 14 consecutive days. Hypercoagulation, which is often associated with diabetes mellitus may lead to several health problems such as thrombosis, stroke & heart attack.

   • Selon Abeysekera RA (2015)

     Extrait We report two unique clinical presentation patterns of star fruit nephrotoxicity following consumption of the fruit as a remedy for diabetes mellitus-the first, in a patient with normal renal function & the second case which we believe is the first reported case of chronic kidney disease (CKD) due to prolonged and excessive consumption of star fruits. Star fruit (Averrhoa carambola) is commonly consumed as an herbal remedy for various ailments in tropical countries.

   • Selon Ayesh S SM (2013)

     Extrait Averrhoa carambola L. carambola was used in ailments such as arthralgia, chronic headache, boils & pyodermas, colds, cough, epistaxis, spermatorrhea, fever, food poisoning, gastroenteritis, malaria, malarial splenomegaly, oliguria, postpartum edema, sore throat, subcalorism & traumatic injury.

   • Selon Gunasekaran LCA (2011)

     Extrait Averrhoa carambola (star fruit) leaves have been a part of traditional medicine used in Ayurvedic preparations to treat DM in Sri Lanka. Researchers have investigated the hypoglycaemic effects of several insoluble fiber-rich fractions (FRFs) including insoluble dietary fiber, alcohol-insoluble solid & water insoluble solid from the pomace of AC.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.