Bacopa monnieri (Ti-véronik) : vertus médicinales en extraction alcoolique

Bacopa monnieri (Ti-véronik, Kinin-pavé, petite-Véronique, Quinine-des-pavés, Ti-veronik) — famille Scrofulariacées.

Synonymes scientifiques : Bacopa monnieri-(L)-West, Bramia indica-Lam, lysimachia monnieri-L, monniera africana-Pers, monnieria monnieria-Britt, septas reptans-L.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 24 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 124 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Partie aerienne. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ghosh T (2008)

     Extrait The extract produced significant decrease in the blood glucose level when compared with the controls in alloxan induced hyperglycemic rats both in the single dose as well as multiple dose experiment at the tested dose level and is comparable with the standard drug Glibenclamide. This article describes the antihyperglycaemic activity, in vivo antioxidant potential, effect on glycosylation of hemoglobin and in-vitro peripheral utilisation of glucose of the ethanolic extract of the aerial parts of B monnieri.

   • Selon Ghosh T (2014)

     Extrait Ghosh T et al, Antihyperglycemic activity of stigmasterol isolated from Bacopa monnieri Linn aerial parts against alloxan induced diabetic rats.

   • Selon Upadhyay P (2015)

     Extrait In this study we explored a new pharmacological intervention by investigating the neuroprotective effects of a standardized polyherbal formulation (PF) [(Bacopa monnieri (20 mg/kg), Hippophaé rhamnoides (25 mg/kg) & Dioscorea bulbifera (15 mg/kg), p.o] on passive avoidance learning (PAL) & memory in normal & streptozotocin (STZ) induced diabetic rats. Type II diabetes mellitus (T2DM) leads to elevated levels of plasma glucose & causes neurological complications including impairment of learning & memory processes.

2. 2

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Partie aerienne.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ghosh T (2007)

     Extrait The ethanolic extract of Bacopa monnieri Aerial parts were studied for its hepatoprotective effect on CCl₄-induced Hepatotoxic rats. The extract was also found to decrease significantly the CCl₄-induced elevation of lipid peroxidation & increase the activity of antioxidant enzymes (SOD & CAT) & GSH level in the liver of extract treated rats when compared with CCl₄ induced rats.CAT) & GSH level in the liver of extract treated rats when compared with CCl₄ induced rats.

   • Selon Ghosh T (2008)

     Extrait This article describes the antihyperglycaemic activity, in vivo antioxidant potential, effect on glycosylation of hemoglobin and in-vitro peripheral utilisation of glucose of the ethanolic extract of the aerial parts of B monnieri. Administration of the extract & Glibenclamide significantly decreased the levels of TBARS, increased the content of GSH and increased the activity of SOD & CAT in liver of diabetic rats.

   • Selon Gomathinayagan R (2004)

     Extrait Antioxidant enzymes such as catalase (CAT), superoxide dismutase (SOD), glutathione peroxidase (GPx) & the levels of glutathione (GSH) & the rate of lipid peroxidation (LPO) in the liver & kidney tissues were assessed.

3. 3

   Douleur inflammatoire, rhumatisme

   Partie usitée : Feuille. Profil pharmacologique documenté : Diclofenac-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Russo A (2005)

     Extrait Bacopa monnieri (BM), a traditional Ayurvedic medicine, used for centuries as a memory enhancing, anti-inflammatory, analgesic, antipyretic, sedative & antiepileptic agent. In addition, researchers have evaluated the anti-inflammatory, cardiotonic & other pharmacological effects of BM preparations/ extracts.

   • Selon Valotto-Neto LJ (s.d.)

     Extrait Bacopa monnieri (BM), an herb with active compounds, such as bacosides A & B, betulinic acid, loliolide, asiatic acid, & quercetin, demonstrates the potential for brain health. BM has anti-apoptotic & antioxidant actions and can repair damaged neurons, stimulate kinase activity, restore synaptic function, improve nerve transmission, & increase neuroprotection.

   • Selon SRIVASTATA P (2024)

     Extrait However, it is vital to comprehend the active phytochemical components of Bacopa monnieri extract (BME) & their molecular mechanisms in order to better grasp the effect of BME on neurological illnesses & diseases. The popular perennial creeping plant known as Bacopa monnieri (also known as Brahmi) is being utilized in the Indian Ayurvedic medicine practice.

   • Selon Hossain H (2007)

     Extrait Hossain H et al, Evaluation of Analgesic, Antidiarrhoeal & Cytotoxic Activities of Ethanolic Extract of Bacopa monnieri (L), British J of Pharmaceut Res, 2 :3, 2007-Aims: The crude ethanolic leaf extract of Bacopa monnieri (L) Penn. Conclusion: Therefore, the obtained results tend to suggest the antinociceptive, Antidiarrhoeal & cytotoxic activities of crude ethanolic extract of BM leaves & thus provide the scientific basis for the traditional uses of this plant part as a remedy for pain & diarrhoea.

   • Selon Patil A (2014)

     Extrait The various ethnomedicinal uses mentioned are antitumor, against anxiety & depression, epilepsy, against bronchitis & asthma, gastrointestinal disorders, cardiovascular effects, hypothyroidism, anticonvulsant, analgesic, anti-inflammatory, antioxidative activity, antipyretic & antistress. Out of the various extracts & cell lines used for studying anticancer activity, the ethanolic extract of Bacopa monnieri was active on Human Breast Cancer Cell Line (MDA–MB-468).

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.