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Broussonetia papyrifera (Les 3 rois mages) : vertus médicinales en extraction alcoolique

Broussonetia papyrifera (Les 3 rois mages, Murier de Chine, The Three Wise Men, Chinese mulberry) — famille Moracées.

Synonymes scientifiques : Morus papyrifera L., Papyrius papyrifera (L.) Kuntze.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 8 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 112 références scientifiques pour cette espèce (détail intégral dans l’application).

Indications thérapeutiques en extraction alcoolique :

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

  1. Diabete mellitus de type II

    Partie usitée : Racine.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Extrait (2012) — extrait : Plants belonging to the genus Broussonetia (Moraceae), which grow naturally in Asian & Pacific countries, have long been used in traditional Chinese medicine to treat various conditions, particularly tinea, dysentery, hernia & oedema. Antidiabetic & antitumoural properties seem possible, but need further support.

    • Selon Lee JA (s.d.)

      Extrait In this study, we investigated the effects of extracts of Broussonetia papyrifera root bark (PRE) & its bioactive components on inflammation & insulin sensitivity. The chronic low-grade inflammation in adipose tissue plays a causal role in obesity-induced insulin resistance & its associated pathophysiological consequences.

    • Selon Auteur (2022)

      Extrait The keywords for searching included “paper mulberry”, “Broussonetia papyrifera”, “skin-lightening”, “skin-whitening”, “depigmentation”, “pharmacological activity”, & “biological activity”. Apart from its anti-tyrosinase activity, paper mulberry and its compounds exhibited anti-inflammatory, antioxidant, antimicrobial, antiviral, anticancer, antidiabetic, anticholinesterase, antigout, antinociceptive, and hepatoprotective effects.

    • Selon CHEN Y (2022)

      Extrait The Broussonetia genus (Moraceae), recognized for its value in many Chinese traditional herbs, mainly includes Broussonetia papyrifera (L.) L'Hér. Moreover, its active compounds & extracts have exhibited a variety of pharmacological effects such as antitumor, antioxidant, anti-inflammatory, antidiabetic, anti-obesity, antibacterial, & antiviral properties, & its use against skin wrinkles.

    • Selon Nguyen LTH (2022)

      Extrait The keywords for searching included “paper mulberry”, “Broussonetia papyrifera”, “skin-lightening”, “skin-whitening”, “depigmentation”, “pharmacological activity”, & “biological activity”. Apart from its anti-tyrosinase activity, paper mulberry & its compounds exhibited anti-inflammatory, antioxidant, antimicrobial, antiviral, anticancer, antidiabetic, anticholinesterase, antigout, antinociceptive, & hepatoprotective effects.

  2. Cancer traitement adjuvant du carcinome hépatique

    Partie usitée : Écorce.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon SI B (2018)

      Extrait This study was carried out to investigate the possible application of Broussonetia papyrifera (B. papyrifera) silage as a functional feeding stuff in dairy cattle.

    • Selon XU B (2022)

      Extrait This study aimed to evaluate the effects of Broussonetia papyrifera polysaccharide (BPP) on liver injury & intestinal flora induced by APAP. Overall, BPP was a potential hepatoprotective drug that could protect against APAP-induced liver injury & might be mediated by intestinal flora.

    • Selon NIU K (2023)

      Extrait The gene expression related to hepatic lipid metabolism including acetyl-CoA carboxylase, fatty acid synthase, & peroxisome proliferator-activated receptor (PPARα) was down-regulated whereas liver X receptor was up-regulated in LfBP1 group. Hybrid Broussonetia papyrifera (BP) has been widely planted & commonly used as ruminant forage source after fermentation in China.

    • Selon Wang, Q (2024)

      Extrait Wang, Q et al, Total Flavonoids of Broussonetia Papyrifera Alleviate Non-Alcohol Fatty Liver Disease via Regulating Nrf2/AMPK/mTOR Signaling Pathways.

    • Selon Auteur (2022)

      Extrait Apart from its anti-tyrosinase activity, paper mulberry and its compounds exhibited anti-inflammatory, antioxidant, antimicrobial, antiviral, anticancer, antidiabetic, anticholinesterase, antigout, antinociceptive, and hepatoprotective effects. The keywords for searching included “paper mulberry”, “Broussonetia papyrifera”, “skin-lightening”, “skin-whitening”, “depigmentation”, “pharmacological activity”, & “biological activity”.

  3. Pathologies respiratoires : hyperplasie cellulaire muqueuse, pleurésie, inflammation pulmonaire subaiguë

    Partie usitée : Racine.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Extrait (2012) — extrait : Plants belonging to the genus Broussonetia (Moraceae), which grow naturally in Asian & Pacific countries, have long been used in traditional Chinese medicine to treat various conditions, particularly tinea, dysentery, hernia & oedema. Several active compounds including coumarins, polyphenols, alkaloids, flavonoids, glycosides, lignans & diterpenes have been isolated from the plants of this genus in the past few years, & some members of these constituents have been demonstrated to exert antioxidant, antiinflammatory, antiplatelet, antityrosinase, antimicrobial & antinociceptive effects.

    • Selon Auteur (2021)

      Extrait The general aspects, plant profile, traditional uses, distribution, major phytoconstituents, & significant pharmacotherapeutic attributes (antiviral, anti-cancer, anti-oxidant, cytotoxic potentials, anti-inflammatory, anti-diabetic, anti-microbial, anti-nociceptive, anti-gout, & anti-proliferative) mediated by various parts were all highlighted in this fascinating article. Broussonetia papyrifera, also known as paper mulberry, is a well-known conventional natural resource that has been used for decades, and the renowned advancements must be introduced to researchers for more improvement, product creation, innovative technology exploration, & the discovery of new concepts.

    • Selon GUO P (2023)

      Extrait Broussonetia papyrifera is rich in flavonoids, which have significant antioxidant, antibacterial, & anti-inflammatory activities and certain pharmacological activities. papyrifera: Several important enzyme genes involved in flavonoid production pathways have been discovered.

    • Selon Auteur (2022)

      Extrait Apart from its anti-tyrosinase activity, paper mulberry and its compounds exhibited anti-inflammatory, antioxidant, antimicrobial, antiviral, anticancer, antidiabetic, anticholinesterase, antigout, antinociceptive, and hepatoprotective effects. The keywords for searching included “paper mulberry”, “Broussonetia papyrifera”, “skin-lightening”, “skin-whitening”, “depigmentation”, “pharmacological activity”, & “biological activity”.

    • Selon CHEN Y (2022)

      Extrait Moreover, its active compounds & extracts have exhibited a variety of pharmacological effects such as antitumor, antioxidant, anti-inflammatory, antidiabetic, anti-obesity, antibacterial, & antiviral properties, & its use against skin wrinkles. The Broussonetia genus (Moraceae), recognized for its value in many Chinese traditional herbs, mainly includes Broussonetia papyrifera (L.) L'Hér.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.

Évolution de cette fiche publique

Sous le CTA · journal des mises à jour

Contenu

−1 synergie · +8 références · −8 références

Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.

−1 synergie+8 références−8 références
+8 références — afficher les textes
Lin CN et al, Revised structure of broussoflavonol G & the 2D NMR spectra of some related prenylflavonoids. Phytochem,  41:  1215–7. 1996a.Lin CN

Lin CN et al, Revised structure of broussoflavonol G & the 2D NMR spectra of some related prenylflavonoids. Phytochem,  41:  1215–7. 1996a.

Ajoutée
PARK JY et al, evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors, Jl of Enzyme Inhibition & Med Chem, 22:1, 2017-Abstract: The current study was designed to assPARK JY · 2017

PARK JY et al, evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors, Jl of Enzyme Inhibition & Med Chem, 22:1, 2017-Abstract: The current study was designed to assess the inhibitory activity of Broussonetia papyrifera-derived polyphenols against 3-chymotrypsin-like & papain-like coronavirus cysteine proteases. The isolated compounds were broussochalcone B (1), broussochalcone A (2), 4—hydroxy-iso-lonchocarpin (3), papyriflavonol A (4), 3′-(3-methylbut-2-enyl)-3′,4,7-trihydroxyflavane (5), kazinol A (6), kazinol B (7), broussoflavan A (8), kazinol F (9), …

Ajoutée
Lin CN et al.  Novel antiplatelet constituents from formosan moraceous plants. J Nat Prod  59:  834–8. 1996b-Abstract : Sixteen constituents from Formosan Moraceous plants were tested for their antiplLin CN

Lin CN et al.  Novel antiplatelet constituents from formosan moraceous plants. J Nat Prod  59:  834–8. 1996b-Abstract : Sixteen constituents from Formosan Moraceous plants were tested for their antiplatelet activities in rabbit platelet suspension and human platelet-rich plasma. Cycloartocarpin A, cycloheterophyllin, broussochalcone A, kazinol A, broussoaurone A, & broussoflavonol F showed strong inhibition of arachidonic acid (AA)-induced platelet aggregation. Of the compounds tested, broussochalcone A exhibited the most potent inhibition of platelet aggregation induced by AA (IC50 = 6.8 μ…

Ajoutée
Park JY et al, Evaluation of polyphenols from Broussonetia papyrifera &s coronavirus protease inhibitors J of Enzyme Inhibitors & Med Chem, 2017; 32(1),.2016-Abstract: The current study was designed tPark JY · 2017

Park JY et al, Evaluation of polyphenols from Broussonetia papyrifera &s coronavirus protease inhibitors J of Enzyme Inhibitors & Med Chem, 2017; 32(1),.2016-Abstract: The current study was designed to assess the inhibitory activity of Broussonetia papyrifera-derived polyphenols against 3-chymotrypsin-like & papain-like coronavirus cysteine proteases. The isolated compounds were broussochalcone B (1), broussochalcone A (2), 4-hydroxyi-solonchocarpin (3), papyriflavonol A (4), 3′-(3-methylbut-2-enyl)-3′,4,7-trihydroxyflavane (5), kazinol A (6), kazinol B (7), broussoflavan A (8), kazinol F (…

Ajoutée
Ryu HW et al, Anticholinesterase potential of flavonols from paper mulberry (Broussonetia papyrifera) & their kinetic studies  Food Chem, 2012; 132(3): 1244-50-Abstract: Ethanol extracts of paper mulbRyu HW · 2012

Ryu HW et al, Anticholinesterase potential of flavonols from paper mulberry (Broussonetia papyrifera) & their kinetic studies  Food Chem, 2012; 132(3): 1244-50-Abstract: Ethanol extracts of paper mulberry were found to display significant inhibition against cholinesterases, enzymes that are strongly linked with Alzheimer's disease (AD). The active components were identified as prenylated flavonols (2-4) that inhibited two related human cholinesterases in a dose-dependent manner, with IC50's ranging between 0.8 & 3.1μM & between 0.5 & 24.7μM against human acetylcholinesterase (hAChE) & butyl…

Ajoutée
Ryu HW et AL, Autoinhibit of Xanthine Oxidase by Phenolic Phytochemicals from Broussonetia papyrifera, J of the Korean Society, 2012-Abstract: The roots of Broussonetia papyrifera were extracted into Ryu HW · 2012

Ryu HW et AL, Autoinhibit of Xanthine Oxidase by Phenolic Phytochemicals from Broussonetia papyrifera, J of the Korean Society, 2012-Abstract: The roots of Broussonetia papyrifera were extracted into four different polar solvents: chloroform, 50% ethanol in water, ethanol, & water. The ethanol extract showed the most potent inhibition (72.3% at 20 g/mL) against xanthine oxidase (XOD). Chromatography of EE yielded nine phenolic phytochemicals, which were confirmed as broussochalcone A (1), brousso-chalcone B (2), 3,4-dihydroxyisolonchocarpin (3), 4-hydroxyisolonchocarpin (4), 3-'(3-methylbut…

Ajoutée
Chen RM et al, Natural PTP1B Inhibitors from Broussonetia papyrifera, Bioorganic & Med Chem Letters, 12(23) :3387-90, 2002-Abstract : Two new compounds, 8-(1,1-dimethylallyl)-5′-(3-methylbut-2-enyl)-3Chen RM · 2002

Chen RM et al, Natural PTP1B Inhibitors from Broussonetia papyrifera, Bioorganic & Med Chem Letters, 12(23) :3387-90, 2002-Abstract : Two new compounds, 8-(1,1-dimethylallyl)-5′-(3-methylbut-2-enyl)-3′,4′,5,7-tetrahydroxyflanvonol (1), 3′-(3-methylbut-2-enyl)-3′,4′,7-trihydroxyflavane (2) & three known compounds 3,3′,4′,5,7-pentahydroxyflavone (3), uralenol (4), broussochalcone A (5) were isolated from the roots of Broussonetia papyrifera, & their structures determined by spectroscopic methods. Compounds 1, 3, 4 & 5 significantly show the inhibitory activities against the PTP1B enzyme. Two …

Ajoutée
Chen RM et al, Natural PTP1B Inhibitors from Broussonetia papyrifera Bioorganic & Medicinal Chem Letters, 2002; 12(23):3387-90-Abstract: Two new compounds, 8-(1,1-dimethylallyl)-5'-(3-methylbut-2-enylChen RM · 2002

Chen RM et al, Natural PTP1B Inhibitors from Broussonetia papyrifera Bioorganic & Medicinal Chem Letters, 2002; 12(23):3387-90-Abstract: Two new compounds, 8-(1,1-dimethylallyl)-5'-(3-methylbut-2-enyl)-3',4',5,7-tetrahydroxyflanvonol (1), 3'-(3-methylbut-2-enyl)-3',4',7-trihydroxyflavane (2) and three known compounds 3,3',4',5,7-penta-hydroxy-flavone (3), uralenol (4), broussochalcone A (5) were isolated from the roots of Broussonetia papyrifera, & their structures determined by spectroscopic methods. Compounds 1, 3, 4 & 5 significantly show the inhibitory activities against the PTP1B enzyme

Ajoutée
Lin CN et al, Revised structure of broussoflavonol G & the 2D NMR spectra of some related prenylflavonoids. Phytochem,  41:  1215–7. 1996a.Lin CN

Lin CN et al, Revised structure of broussoflavonol G & the 2D NMR spectra of some related prenylflavonoids. Phytochem,  41:  1215–7. 1996a.

Retirée
PARK JY et al, evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors, Jl of Enzyme Inhibition & Med Chem, 22:1, 2017-Abstract: The current study was designed to assPARK JY · 2017

PARK JY et al, evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors, Jl of Enzyme Inhibition & Med Chem, 22:1, 2017-Abstract: The current study was designed to assess the inhibitory activity of Broussonetia papyrifera-derived polyphenols against 3-chymotrypsin-like & papain-like coronavirus cysteine proteases. The isolated compounds were broussochalcone B (1), broussochalcone A (2), 4—hydroxy-iso-lonchocarpin (3), papyriflavonol A (4), 3′-(3-methylbut-2-enyl)-3′,4,7-trihydroxyflavane (5), kazinol A (6), kazinol B (7), broussoflavan A (8), kazinol F (9), …

Retirée
Lin CN et al.  Novel antiplatelet constituents from formosan moraceous plants. J Nat Prod  59:  834–8. 1996b-Abstract : Sixteen constituents from Formosan Moraceous plants were tested for their antiplLin CN

Lin CN et al.  Novel antiplatelet constituents from formosan moraceous plants. J Nat Prod  59:  834–8. 1996b-Abstract : Sixteen constituents from Formosan Moraceous plants were tested for their antiplatelet activities in rabbit platelet suspension and human platelet-rich plasma. Cycloartocarpin A, cycloheterophyllin, broussochalcone A, kazinol A, broussoaurone A, & broussoflavonol F showed strong inhibition of arachidonic acid (AA)-induced platelet aggregation. Of the compounds tested, broussochalcone A exhibited the most potent inhibition of platelet aggregation induced by AA (IC50 = 6.8 μ…

Retirée
Park JY et al, Evaluation of polyphenols from Broussonetia papyrifera &s coronavirus protease inhibitors J of Enzyme Inhibitors & Med Chem, 2017; 32(1),.2016-Abstract: The current study was designed tPark JY · 2017

Park JY et al, Evaluation of polyphenols from Broussonetia papyrifera &s coronavirus protease inhibitors J of Enzyme Inhibitors & Med Chem, 2017; 32(1),.2016-Abstract: The current study was designed to assess the inhibitory activity of Broussonetia papyrifera-derived polyphenols against 3-chymotrypsin-like & papain-like coronavirus cysteine proteases. The isolated compounds were broussochalcone B (1), broussochalcone A (2), 4-hydroxyi-solonchocarpin (3), papyriflavonol A (4), 3′-(3-methylbut-2-enyl)-3′,4,7-trihydroxyflavane (5), kazinol A (6), kazinol B (7), broussoflavan A (8), kazinol F (…

Retirée
Ryu HW et al, Anticholinesterase potential of flavonols from paper mulberry (Broussonetia papyrifera) & their kinetic studies  Food Chem, 2012; 132(3): 1244-50-Abstract: Ethanol extracts of paper mulbRyu HW · 2012

Ryu HW et al, Anticholinesterase potential of flavonols from paper mulberry (Broussonetia papyrifera) & their kinetic studies  Food Chem, 2012; 132(3): 1244-50-Abstract: Ethanol extracts of paper mulberry were found to display significant inhibition against cholinesterases, enzymes that are strongly linked with Alzheimer's disease (AD). The active components were identified as prenylated flavonols (2-4) that inhibited two related human cholinesterases in a dose-dependent manner, with IC50's ranging between 0.8 & 3.1μM & between 0.5 & 24.7μM against human acetylcholinesterase (hAChE) & butyl…

Retirée
Ryu HW et AL, Autoinhibit of Xanthine Oxidase by Phenolic Phytochemicals from Broussonetia papyrifera, J of the Korean Society, 2012-Abstract: The roots of Broussonetia papyrifera were extracted into Ryu HW · 2012

Ryu HW et AL, Autoinhibit of Xanthine Oxidase by Phenolic Phytochemicals from Broussonetia papyrifera, J of the Korean Society, 2012-Abstract: The roots of Broussonetia papyrifera were extracted into four different polar solvents: chloroform, 50% ethanol in water, ethanol, & water. The ethanol extract showed the most potent inhibition (72.3% at 20 g/mL) against xanthine oxidase (XOD). Chromatography of EE yielded nine phenolic phytochemicals, which were confirmed as broussochalcone A (1), brousso-chalcone B (2), 3,4-dihydroxyisolonchocarpin (3), 4-hydroxyisolonchocarpin (4), 3-'(3-methylbut…

Retirée
Chen RM et al, Natural PTP1B Inhibitors from Broussonetia papyrifera, Bioorganic & Med Chem Letters, 12(23) :3387-90, 2002-Abstract : Two new compounds, 8-(1,1-dimethylallyl)-5′-(3-methylbut-2-enyl)-3Chen RM · 2002

Chen RM et al, Natural PTP1B Inhibitors from Broussonetia papyrifera, Bioorganic & Med Chem Letters, 12(23) :3387-90, 2002-Abstract : Two new compounds, 8-(1,1-dimethylallyl)-5′-(3-methylbut-2-enyl)-3′,4′,5,7-tetrahydroxyflanvonol (1), 3′-(3-methylbut-2-enyl)-3′,4′,7-trihydroxyflavane (2) & three known compounds 3,3′,4′,5,7-pentahydroxyflavone (3), uralenol (4), broussochalcone A (5) were isolated from the roots of Broussonetia papyrifera, & their structures determined by spectroscopic methods. Compounds 1, 3, 4 & 5 significantly show the inhibitory activities against the PTP1B enzyme. Two …

Retirée
Chen RM et al, Natural PTP1B Inhibitors from Broussonetia papyrifera Bioorganic & Medicinal Chem Letters, 2002; 12(23):3387-90-Abstract: Two new compounds, 8-(1,1-dimethylallyl)-5'-(3-methylbut-2-enylChen RM · 2002

Chen RM et al, Natural PTP1B Inhibitors from Broussonetia papyrifera Bioorganic & Medicinal Chem Letters, 2002; 12(23):3387-90-Abstract: Two new compounds, 8-(1,1-dimethylallyl)-5'-(3-methylbut-2-enyl)-3',4',5,7-tetrahydroxyflanvonol (1), 3'-(3-methylbut-2-enyl)-3',4',7-trihydroxyflavane (2) and three known compounds 3,3',4',5,7-penta-hydroxy-flavone (3), uralenol (4), broussochalcone A (5) were isolated from the roots of Broussonetia papyrifera, & their structures determined by spectroscopic methods. Compounds 1, 3, 4 & 5 significantly show the inhibitory activities against the PTP1B enzyme

Retirée

Par Emmanuel Nossin · ethnopharmacologue

Contenu

+1 indication · +1 synergie

Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.

+1 indication+1 synergie

Par Emmanuel Nossin · ethnopharmacologue

Contenu

Première publication publique

Nouvelle plantetop 3 · nb refs

Par Emmanuel Nossin · ethnopharmacologue