Cajanus cajan (Pwa dangôl) : vertus médicinales en extraction alcoolique

Cajanus cajan (Pwa dangôl, Pois d’Angole, Angolan peas) — famille Fabacées.

Synonymes scientifiques : ---------.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 17 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 47 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glimepiride-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Manzo JAM (2017)

     Extrait Aims: Aims and objectives are to evaluate the effects of ethanolic extracts of Cajanus cajan (CCEE) leaves on its Antihyperglycemic effects on BGL of normoglycemic mice. Diabetes mellitus is a metabolic disease that is usually associated with abnormalities in the metabolism of different substrates leading to high blood glucose levels (BGL).

   • Selon Ezike AC (2010)

     Extrait Ezike AC et al, Experimental evidence for the antidiabetic activity of Cajanus cajan leaves in rats.

   • Selon Brito SA (2012)

     Extrait Brito SA et al, Evaluation of the antifungal activity and modulation between Cajanus cajan (L.) Millsp leaves and roots ethanolic extracts and conventional antifungals, Pharmacogn Mag 2012, 8 (30): 103-6.-BACKGROUND: The use and investigation of natural products with antimicrobial activity from vegetal source have been reported by several researchers. MATERIALS & METHODS: This study shows the characterization of secondary metabolites present in ethanolic extracts from leaves and roots of Cajanus cajan by phytochemical prospection.

2. 2

   Hépatite, stéatose hépatique, cirrhose

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Akinoye AO (2011)

     Extrait The aim of the study to investigate the hepatoprotective effect of the C cajan ethanolic extract on hepatic antioxidant status in D-galactosamine-induced hepatitis rats by measuring the extent of oxidative damage as well as the state of the antioxidant defense system. Material & Methods: Ethanolic extract of C cajan was administered orally (100mg/kg body weight) and the effect of the extract on the activities of Alanine Aminotransferase, Aspartate Aminotransferase, Catalase, Superoxide Dismutase, Glutathione Peroxidase, Glutathione-S-transferase as well as the levels of Malondialdehyde and reduced glutathione were estimated in D-galactosamine induced hepatitis rats.

   • Selon Sinha MP (s.d.)

     Extrait Since the protein possess hepatoprotective activity, it may first ameliorate GalN-induced liver damage & consequently the renal disorders are reduced. As GalN induced severe hepatotoxicity followed by renal failure, the protective role of the protein against GalN induced renal damages is likely to be an indirect effect.

   • Selon MANNA P (2007)

     Extrait The present study was conducted to determine the protective role of a 43-kD protein isolated from the leaves of the herb Cajanus indicus L against D (+)-galactosamine (GalN) induced liver damage in mice. Results suggest that GalN caused hepatic damages via oxidative insult & that the protein provided protection through its antioxidant mechanism,.

   • Selon MANNA P (2007)

     Extrait The herb, Cajanus indicus L, is well known for its hepatoprotective action. This exposure significantly altered the activities of the antioxidant enzymes like superoxide dismutase (SOD), catalase (CAT), glutathione-S-transferase (GST), glutathione reductase (GR) & the cellular metabolites such as reduced glutathione (GSH), oxidized glutathione (GSSG), total thiols, lipid peroxidation end products in liver & kidney compared to the normal mice.

   • Selon Prema L (1973)

     Extrait Prema L et al, Effect of protein fractions from Cajanus cajan (red gram) & Dolichos biflorus (horse gram) on the serum, liver & aortic lipid levels in rats fed a high-fat-high-cholesterol diet.

3. 3

   Infection bactérienne : Bacillus subtilis, staphylococcus aureus, Streptococcus pneumonia, Salmonella typhi, Klebsiella pneumoniae, Escherichia coli, Pseudomonas aeruginosa

   Partie usitée : Feuille.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Pratima H (2011)

     Excerpt were extracted in various organic solvents such as pet ether, chloroform, methanol, ethanol & aqueous & were tested against Bacillus subtilis, staphylococcus aureus, Streptococcus pneumonia, Salmonella typhi, Klebsiella pneumoniae, Escherichia coli, & Pseudomonas aeruginosa using agar well diffusion method. The ethanolic extract showed the highest activity on all the Gram-positive bacteria & Gram-negative bacteria Klebsiella pneumonia at 100mg/mL, whereas Pseudomonas aeruginosa was resistant to all the extracts except ethanol.

   • Selon Hasan SF (2013)

     Excerpt Antibacterial activities of four different extracts of Cajanus cajan L. For characterization of Bacillus spp the PCR amplified 16S rDNA were sequenced and individual sequence was compared with NCBI database information using BLAST search.

   • Selon Brito SA (2012)

     Excerpt Brito SA et al, Evaluation of the antifungal activity and modulation between Cajanus cajan (L.) Millsp leaves and roots ethanolic extracts and conventional antifungals, Pharmacogn Mag 2012, 8 (30): 103-6.-BACKGROUND: The use and investigation of natural products with antimicrobial activity from vegetal source have been reported by several researchers. MATERIALS & METHODS: This study shows the characterization of secondary metabolites present in ethanolic extracts from leaves and roots of Cajanus cajan by phytochemical prospection.

   • Selon Zu YG (2010)

     Excerpt Zu YG et al, Chemical composition of SFE-CO2 extracts from Cajanus cajan (L.) Huth & their antimicrobial activity in vitro & in vivo.

   • Excerpt Selon Zu Y (2010) — extrait :

   • Excerpt According to our findings, a therapeutic application of Cajanus ethanolic extracts containing crème or ointment as antiviral agent in recurrent HSV infection appears to be promising. Aqueous and ethanolic extracts of Cajanus cajan (Fabaceae) were examined in vitro for their antiviral activity against herpès simplex virus type 1 (HSV-1) and type 2 (HSV-2).

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.