Capparis spinosa (Gwo Mouzanmbé :Gwo kaya) : vertus médicinales en extraction alcoolique

Capparis spinosa (Gwo Mouzanmbé :Gwo kaya, Babinn chat, Zèb-djab, Gros Mouzambé, gros Acaya, babine -à-chat, herbe grasse, Gwo Mouzanmbé: Gwo kaya, Big Mouzambé, Big Acaya, cat’s lip, fatty grass) — famille Capparacées.

Synonymes scientifiques : Capparis ovata auct non Desf, Cleome pingens-Willd.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 21 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 170 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome colorectal, hépatique & mammaire

   Partie usitée : Parties aeriennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon SUN Y (2023)

     Extrait spinosa possesses various biological activities, including antioxidant, antidiabetic, anticancer, hepatoprotective, neuroprotective, anti-inflammatory, anti-arthritic, antibacterial, & insecticidal effects. as a potential source of nutrition & its health benefits in foods: A comprehensive review of its phytochemistry, bioactivities, safety, & application, Food Chem, 409 :135258, 2023-Absract: Capparis spinosa L.

   • Selon Aichour R (2018)

     Extrait the aim of this study was to evaluate anti-inflammatory & hepatoprotective effects of methanolic extracts from fruits & leaves of Capparis spinosa. For hepatoprotective activity, liver injury was induced in male Wistar mice by administration of CCl4 (1 ml / kg of CCl4 30% in olive oil,), while CS leaf extract (CSLE) & fruit extract (CSFE) were administered orally to the experimental animals.

   • Selon Kalantari H (2018)

     Extrait Among these fractions, hydroalcoholic extract was used to assess the hepatoprotective effect in tert-butyl hydroperoxide (t-BHP) induced hepatotoxicity model by determining serum biochemical markers, sleeping time & antioxidant assay such as reduced glutathione (GSH) as well as histopathological examination of liver tissues. The present study investigates the antioxidant and hepatoprotective effects of Capparis spinosa L.

   • Selon Mollica A (2017)

     Extrait In this study, the nutraceutical potential of Capparis spinosa L. At the end of the experiment, animals were sacrificed, blood taken for assessment of lipid profile and liver/kidney biochemistry while section of the pancreas, kidneys were processed for general histology.

   • Selon Abkari (2015)

     Extrait histopathological examinations showed that liver steatosis, inflammation, & hepatic fibrosis were markedly attenuated in response to CS & fenofibrate interventions. Capparis spinosa (CS) belongs to the family of Capparidaceae & is a traditional plant used to treat various diseases, particularly dyslipidemia.

2. 2

   Troubles hépatiques: anormalité des paramètres sériques: ALT, ALP, AST, MDA, GSH, SOD, Catalase

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Kalantari H (2018)

     Extrait Among these fractions, hydroalcoholic extract was used to assess the hepatoprotective effect in tert-butyl hydroperoxide (t-BHP) induced hepatotoxicity model by determining serum biochemical markers, sleeping time & antioxidant assay such as reduced glutathione (GSH) as well as histopathological examination of liver tissues. The present study investigates the antioxidant and hepatoprotective effects of Capparis spinosa L.

   • Selon SUN Y (2023)

     Extrait spinosa possesses various biological activities, including antioxidant, antidiabetic, anticancer, hepatoprotective, neuroprotective, anti-inflammatory, anti-arthritic, antibacterial, & insecticidal effects. as a potential source of nutrition & its health benefits in foods: A comprehensive review of its phytochemistry, bioactivities, safety, & application, Food Chem, 409 :135258, 2023-Absract: Capparis spinosa L.

   • Selon Yusufoglu H (2014)

     Extrait Both extracts displayed hepatoprotective effect in a dose dependent manner as evident by reduced levels of serum ALT, AST, ALP, γ-GT & hepatic MDA concentration, as well as higher CAT, GPx, SOD activities & GSH concentration compared to TAA-intoxicated controls. The aim of this study was to investigate the hepatoprotective effect of Allium paniculatum L & Capparis spinosa L.

   • Selon Mollica A (2017)

     Extrait Results showed that the regular administration of CS leaf or buds normalized all the biochemical parameters & reversed the liver/kidney injury with variable degrees of organ protection. In this study, the nutraceutical potential of Capparis spinosa L.

   • Selon Ali Al-Nuani RM (2020)

     Extrait The aqueous Capparis spinosa extract (CSE)(500 mg/kg) was used to reduce the hepatotoxicity induced by paracetamol (PARA)(300mg/kg). Many of the hepatoprotective of plant use in medicine to treatment of hepatic disorders.

3. 3

   Diabete mellitus de type II

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Huseini H.F (2013)

     Extrait Design: The present study was undertaken to explore the possible anti-hyperglycemic effects of the CS fruit extract in type 2 diabetic patients. Conclusions: CS fruit extract may be a safe anti-hyperglycemic & anti-hypertriglyceridaemic agent for type 2 diabetic patients.

   • Selon Perna S (2023)

     Extrait RCTs with CS fruit supplementation or consumption in different cohorts of subjects with non-alcoholic fatty liver disease (NAFLD), Type-2-Diabetes (T2D), metabolic syndrome, & hyperlipidemia were included in this systematic review with a mean intervention duration from 2 to 12 weeks. In conclusion, this systematic review & meta-analysis showed the paucity of data available on the topic while showing the potential role of CS fruit as a promising food for improving the liver-lipid profile axis in patients with metabolic syndrome & diabetes.

   • Selon Jalali MT (2016)

     Extrait The present study aimed to investigate the effects of administration of Capparis spinosa (CS) fruit aqueous extract on liver metabolism in streptozotocin (STZ)-induced diabetic rats. The aqueous extract of CS was orally administered at a dose of 20mg/kg for 28 consecutive days & then its effects on blood glucose, lipid & insulin levels in normal & STZ diabetic rats were comparatively investigated.

   • Selon Kazemian M (2015)

     Extrait Conclusion: These results showed that CS root extract could improve diabetic related metabolic derangement such as hyperglycemia, dyslipidemia, & elevated liver markers in an insulin-independent manner,. Rats were rendered diabetic (streptozotocin 60 mg/kg, i.p.) & treated with 0.2, 0.4 g/ kg of plant extract or Glibenclamide for four weeks.

   • Selon Eddouks M (2005)

     Extrait The purpose of this study was to examine the effect of single & repeated oral administrations of the aqueous extract of Capparis spinosa L. (CS) at a dose of 20mg/kg on lipid metabolism in normal & streptozotocin-induced diabetic rats.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.