Carum carvi (Carvi) : vertus médicinales en extraction alcoolique

Carum carvi (Carvi, Cumin des Montagnes, Caraway, Mountain Cumin) — famille Apiacées.

Synonymes scientifiques : Carum carvi-(L)-Cranz, falcaria carifolia-CAM, Foenicumul carvi-(L)-Link, Pimpinella carvi-(L)-Jess, Sium carvi-(L)-Benth.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 11 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 60 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Semence. Association synergique mentionnée : Hibiscus sabdariffa-calice.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Auteur (2020)

     Extrait The present study aimed to determine the hypoglycemic effect of Afghan Hibiscus sabdariffa L & Carum Carvi L. Streptozotocin-induced diabetic rats were administered intraperitoneally with hydro-alcoholic extracts of Hs (75, 150 & 300 mg/kg), CC (150, 300 & 500 mg/kg) & their combinations for 21 days.

   • Selon Hajlaoui H (2021)

     Extrait Therefore, this study aims to perform a chemical analysis of both essential oils (EOs) from the seeds of Carum carvi (C. A high & equipotent antidiabetic activity was observed for the mixture (IC50 = 0.75 ± 0.15 mg/mL) when compared to the standard drug, acarbose, which is about nine times higher than each EO alone.

   • Selon Lemhadri A (2006)

     Extrait The purpose of this study was to examine the effect of single & repeated oral administration of the aqueous extract of Carum carvi fruits at a dose of (20mg/kg) on lipid metabolism in normal & streptozotocin-induced diabetic rats (STZ). In STZ diabetic rats, cholesterol levels were decreased significantly 6h after Carum carvi treatment (p<0.05).

   • Selon Abou El-Soud NH (2014)

     Extrait Thirty male albino rats were divided into three groups: normal control (group A), diabetic positive control (group B), & experimental (group C) receiving C carvi oil as a renoprotective agent at 10 mg/kg of body weights orally. This could be contributed to Carum carvi constituents, especially carvone γ –Terpinene & Limonene which have strong antioxidant activity.

   • Selon Haidari F (2011)

     Extrait To evaluate the effect of oral administration of caraway (Carum carvi) on the blood glucose level, lipid profile, & the weight of diabetic rats. Diabetes was induced by intraperitoneal injection of 60 mg/kg body weight streptozotocin.

2. 2

   Cancer : traitement adjuvant de la leucémie

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Naghibi SM (2015)

     Extrait Observing this dramatic change in TSH level by Carum ingestion, C carvi capsules was produced and one of the researchers tried the medication on herself with a dose of 40 mg/kg/day. We report a patient with papillary thyroid carcinoma who were under treatment with levothyroxine and experienced an elevated TSH level by ingestion of C carvi.

   • Selon Kamaleeswari M (2006)

     Extrait Thus, our study showed that caraway supple-mentation at a dose of 60mgkg had a modulatory role on tissue LPO, antioxidant profile and prevented DMH-induced histopathological lesions in colon cancer rats. To induce colon cancer, rats were given a weekly subcutaneous injection of1, 2-dimethylhydrazine (DMH) at a dose of 20mgkg (based on body weight) for the first 15 weeks.

   • Selon Zheng Q (1992)

     Extrait Bioassay-directed fractionation of dill weed oil & caraway oil, respectively, from the plants Anethum graveolens L. The alpha, beta-unsaturated ketone system in carvone appeared to be critical for the high enzyme-inducing activity.

   • Selon Aly A (2022)

     Extrait Furthermore, the caraway essential oils indicated anticancer activity against the two cell lines studied; colorectal adenocarcinoma (Caco-2) & liver cancer cell line (HepG-2) as reduced the cell viability & density. Additionally, the caraway EOs have anticancer activity against the two cell lines studied; colorectal adenocarcinoma (Caco-2) & liver cancer cell line (HepG-2) as reduced the cell viability & density.

   • Selon Bogucka-Kocka A (2008)

     Extrait The apoptotic activities of seven ethanol extracts from fruits of seven species of Apiaceae, Eryngium planum, Archangelica officinalis, Pastinaca sativa, Heracleum sibiricum, Carum carvi, Foeniculum vulgare, Levisticum officinale against ML-1--human acute myeloblastic leukaemia, J-45.01--human acute T cell leukaemia, EOL--human eosinophilic leukaemia, HL-60--human Caucasian promyelocytic leukaemia, 1301--human T cell leukaemia lymphoblast, C-8166--human T cell leukaemia, U-266B1--human myeloma, WICL--human Caucasian normal B cell, and H-9--human T cell, were investigated.

3. 3

   Colite, maladie inflammatoire intestinale, maladie de Chron

   Partie usitée : Semence. Profil pharmacologique documenté : Asacol-like, Prednisolone-like, Hydrocortisone-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Keshavarz A (2013)

     Extrait Anti-inflammatory, spasmolytic, antimicrobial, antioxidant, carminative and immunomodulatory properties of caraway suggest that it might exert beneficial effects on inflammatory bowel disease (IBD). Therefore, this study was carried out to investigate the effects of caraway hydroalcoholic extract (CHE) and its essential oil (CEO) in an immunological model of colitis in rats induced by trinitrobenzene sulfonic acid (TNBS).

   • Selon Naghibi SM (2015)

     Extrait Observing this dramatic change in TSH level by Carum ingestion, C carvi capsules was produced and one of the researchers tried the medication on herself with a dose of 40 mg/kg/day. Carum carvi is a widely available herb that has been used as a food additive and as a medication in traditional medicine for many years.

   • Selon Roome T (2021)

     Extrait Digas colic drops (DCD-684) a polyherbal formulation containing Carum carvi, Foeniculum vulgare, Mentha arvensis, Mentha piperita & Zingiber officinale is widely used in Pakistan against gastrointestinal ailments including infantile colic. However, at 18 & 36 ml/kg.bw, liver demonstrated mild inflammation correlating with raised aspartate transaminase (AST), alkaline phosphatase (ALP) & alpha fetoprotein (AFP) levels.

   • Selon Roome T (2021)

     Extrait Digas colic drops (DCD-684) is a polyherbal formulation containing decoctions of five medicinal plants namely Carum carvi L., Foeniculum vulgare Mill, Mentha arvensis L., Mentha piperita L. Thereby, providing the pharmacological basis of its therapeutic use in the gastrointestinal motility disorders & related inflammatory ailments.

   • Selon Yosefi SS (2014)

     Extrait Yosefi SS et al, Effectiveness of Carum carvi on early return of bowel motility after caesarean section.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.