Casearia sylvestris (Pis-chien) : vertus médicinales en extraction alcoolique

Casearia sylvestris (Pis-chien, Ti-kafé mawon, Puce-à-chien, Petit café marron, Dog poo, Dog flea, Little brown coffee) — famille Flacourtiacées.

Synonymes scientifiques : Casearia samyda-C.F., Guidonia sylvestris-(Sw)-Maza, Samyda parviflora-L, S sylvestris-(Sw)-Poir..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 16 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 58 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome mammaire et d’ascite

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Da Silva S (2009)

     Extrait Since the direct in vitro activity against Ehrlich tumor & Lewis’s lung cancer cells was low, we investigated the effects of MGDE or IGDE treatment on the activity of total natural killer cells from Ehrlich ascites tumor-bearing mice, as a possible explanation for the mechanisms of these compounds in vivo. Both compounds presented similar & low in vitro cytotoxicity against Ehrlich ascites tumor cells & & not present any significant toxicity against Lewis’s lung cancer cells.

   • Selon Bettega FK (2014)

     Extrait Antiproliferative effects in vivo were measured in tumor tissue from Ehrlich ascites-bearing mice through the 3H-thymidine uptake assay & the trypan blue exclusion method Results: In vitro, EC50 values found at 24 h on MCF-7 cells were 141 µg/mL for CAE & 66 µg/mL for f-CHCl3. This article reports the results of an investigation about the antiproliferative effects of C sylvestris on tumor cells in vitro & in vivo.

   • Selon Dos Santos AG (2010)

     Extrait An EtOH extract of the leaves of Casearia sylvestris afforded new clerodane diterpene, Casearin X, together with the known compounds casearins B, D, L, & O, & caseargrewiin F. The diterpenes isolated were cytotoxic to human cancer cell lines, with caseargrewiin F being the most active & the new clerodane, Casearin X, the second active compound with IC (50) values comparable to the positive control Doxorubicin.

   • Selon Itokawa H (1988)

     Extrait Antitumor principles from Casearia sylvestris Sw (Flacourtiaceae), structure élucidation of new clerodane diterpènes by 2-D NMR Spectroscopy Chem Pharm Bull (Tokyo) 1988; 36(4): 1585–8.

   • Selon Itokawa H (1990)

     Extrait New antitumor principles, casearins A–F, for Casearia sylvestris Sw.

2. 2

   Arthrite, arthrose, rhumatisme, œdème

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Esteves I (2005)

     Extrait To investigate the antiulcer & antiinflammatory activities of the essential oil from Casearia sylvestris leaves (EOCS) the following tests were used: rat paw edema, granulomatous tissue test, vascular permeability, writhing test, gastric ulcer stress-induced & evaluation of gastric secretion (pylorus ligation test). With the overall results obtained in this study the authors suggest an anti-inflammatory activity for the EOCS of Casearia sylvestris beyond its anti-ulcer activity.

   • Selon Portella de Campos DL (2015)

     Extrait As in Brazil Casearia sylvestris Sw., popularly known as Guaçatonga is widely used for its analgesic, antiseptic and anti-inflammatory activities, this study sought to evaluate the effects of its hydroalcoholic extract in healing process of burns injuries. The anti-inflammatory & bactericidal effects of C.S suggests a potential therapeutic benefit in the treatment of inflammatory conditions in second-degree scald burn injuries, as well as, counteracting against the in vitro paralysis induced by B.

   • Selon De Campos EP (2015)

     Extrait As in Brazil Casearia sylvestris Sw., popularly known as Guaçatonga is widely used for its analgesic, antiseptic & anti-inflammatory activities, this study sought to evaluate the effects of its hydroalcoholic extract in healing process of burns injuries. Conclusion: The anti-inflammatory & bactericidal effects of CS suggest a potential therapeutic benefit in the treatment of inflammatory conditions in second-degree scald burn injuries, as well as, counteracting against the in vitro paralysis induced by B.

   • Selon Heymans AC (2020)

     Extrait To evaluate the topical anti-inflammatory activity for the crude hydroalcoholic extract of Casearia sylvestris (HCE-CS) in the models of single or multiple administration of croton oil to induce ear edema in mice. Casearia sylvestris is a plant used topically in different communities in Brazil, to treat wounds or promote cutaneous healing.

   • Selon Pierri (2017)

     Extrait Carrageenan-induced paw edema and carrageenan-induced pleurisy assays (rats) were used to evaluate anti-inflammatory activity of ethanolic extract, its fractions and clerodane diterpenes from C. The present study aimed to investigate the anti-inflammatory activity of ethanolic extract from C sylvestris leaves and to identify the compounds responsible for this activity.

3. 3

   Gastralgies : lésion gastrique à Helicobacter pilori

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pierri (2017)

     Extrait The present study aimed to investigate the anti-inflammatory activity of ethanolic extract from C sylvestris leaves and to identify the compounds responsible for this activity. sylvestris leaves was fractionated by solid phase extraction & the chemical composition of extract and fractions were assessed by chromatographic techniques.

   • Selon Esteves I (2005)

     Extrait To investigate the antiulcer & antiinflammatory activities of the essential oil from Casearia sylvestris leaves (EOCS) the following tests were used: rat paw edema, granulomatous tissue test, vascular permeability, writhing test, gastric ulcer stress-induced & evaluation of gastric secretion (pylorus ligation test). With the overall results obtained in this study the authors suggest an anti-inflammatory activity for the EOCS of Casearia sylvestris beyond its anti-ulcer activity.

   • Selon Sertie J A (2000)

     Extrait Antiulcer activity of the crude extract from the leaves of Casearia sylvestris.

   • Selon Ameni AZ (2015)

     Extrait Casearia sylvestris S.w (Salicaceae) is catalogued by the Brazilian Unified Health System as a plant of interest for the Brazilian population with the purpose of treating inflammatory disorders, such as pain and gastrointestinal disorders based on the folk use and some literature about efficacy; however, no toxicological studies concerned the safety of extract fluid of this plant have been reported. sylvestris could be safe even when used over a long period for therapeutic uses proposed by the Brazilian Unified Health System.

   • Selon De Matos E (2007)

     Extrait The antinociceptive properties of Casearia sylvestris Sw. The antinociceptive effect of CS extract in the acetic acid test was prevented by prior treatment with the non-selective opioid receptor antagonist naloxone (1mg/kg; 5.8+/-4.2 & 31.5+/-3.1 writhes in vehicle-treated & naloxone-treated groups, respectively), indicating that the endogenous opioid system is involved in its analgesic mechanism of action.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.