Celtis iguanea (Kwôk-chien) : vertus médicinales en extraction alcoolique
Celtis iguanea (Kwôk-chien, Grat-janmb, Croc-à-chien, gratte-jambe) — famille Ulmacées.
Synonymes scientifiques : Celtis aculeata Sw., Momisia iguanaea (Jacq.) Rose & Standl, Rhamnus iguanaea Jacq., R iguanaeus Jacq..
Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 5 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 18 références scientifiques pour cette espèce (détail intégral dans l’application).
Indications thérapeutiques en extraction alcoolique :
Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).
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Arthrose, arththite; rhumatisme, oedème
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon De Moraes FW (2022)
Extrait The antinociceptive & anti-inflammatory activities of crude ethanolic extract of Celtis iguanaea leaves & their active fractions are reported. In conclusion, the DF showed antinociceptive activity that involves the vanilloid system as well as anti-inflammatory effect & the EAF showed anti-inflammatory activity involving the reduction of TNF-α cytokine.
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Selon RIBEIRO KR (2025)
Extrait This study evaluated the in vitro antioxidant capacity & the in vivo antinociceptive & anti-inflammatory mechanisms of the standardized spray-dried Celtis iguanaea hydroethanolic leaf extract (SDCi). These findings support SDCi as an effective anti-inflammatory & antinociceptive phytopharmaceutical intermediate, with potential applications in managing pain & inflammation,.
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Selon Almeida D.D.S (2024)
Extrait We demonstrated the antinociceptive & anti-inflammatory effects of the ethyl acetate leaf extract of Celtis iguanaea (Jacq.) Sargent (EEAc) in mice. The antinociceptive effect of EAECi is attributed to its anti-inflammatory activity, as evidenced by its anti-hyperalgesic & antiedematogenic effects.
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Selon SAMADD A (2024)
Extrait Their extracts & pure substances have been shown to have the same anticancer, antibacterial, anti-inflammatory, antioxidant, hepatoprotective, cardioprotective, urease-inhibiting, & antidiarrheal properties as their traditional uses. Information on the Celtis genus was obtained from internet sources such as Google Scholar, Web of Science, PubMed, ScienceDirect, & so on by using appropriate keywords, including ethnobotanical, pharmacological, pharmaceutical, bioactivity, phytochemistry, & botanical features of the Celtis genus.
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Selon Zanchet B (2019)
Extrait The leaves are popularly used as anti-inflammatory, in the treatment of body pain & urinary infections. The species Celtis iguanaea (Jacq.) Sarg., (Cannabaceae) is widely distributed in Brazil where it is known as “esporão-de-galo or taleira”.
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Selon De Moraes FW (2022)
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Douleur, hyperalgie,
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon De Moraes FW (2022)
Extrait The antinociceptive & anti-inflammatory activities of crude ethanolic extract of Celtis iguanaea leaves & their active fractions are reported. The oral treatment with dichloromethane fraction (DF; 9 mg/Kg) produced antinociceptive effect in both phases of formalin test; however, the treatment with ethyl acetate fraction (EAF; 16 mg/Kg) reduced pain only in the second phase of this test.
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Selon RIBEIRO KR (2025)
Extrait This study evaluated the in vitro antioxidant capacity & the in vivo antinociceptive & anti-inflammatory mechanisms of the standardized spray-dried Celtis iguanaea hydroethanolic leaf extract (SDCi). These findings support SDCi as an effective anti-inflammatory & antinociceptive phytopharmaceutical intermediate, with potential applications in managing pain & inflammation,.
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Selon Leite da Veiga M (2016)
Extrait Celtis iguanaea is popularly known as “Esporão-de-galo” in Portuguese and its leaves are traditionally used in infusion forms as analgesic, antiasthmatic, digestive & diuretic. The aim of this study was to assess the acute & sub-acute toxicity of the crude extract from the Celtis iguanaea leaves in male rats.
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Selon Almeida D.D.S (2024)
Extrait We demonstrated the antinociceptive & anti-inflammatory effects of the ethyl acetate leaf extract of Celtis iguanaea (Jacq.) Sargent (EEAc) in mice. The antinociceptive effect of EAECi is attributed to its anti-inflammatory activity, as evidenced by its anti-hyperalgesic & antiedematogenic effects.
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Selon Rodrigues-Martin JL (2014)
Extrait The hydroxyl-linolenic acid, linoleic acids & conjugated oxo-linoleic acids are among the phytoconstituents that were identified in the Celtis iguanaea HE,. Celtis iguanaea (Canabaceae) is popularly known as esporão-de-galo, stands out among the medicinal plants used for treatment of gastric ulcers.
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Selon De Moraes FW (2022)
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Dyslipidémie : hypercholestérolémie, hyperlipidémie, hypertlyglycidérémie
Références scientifiques (courts extraits)
Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.
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Selon ZANCHET B (2018)
Extrait Celtis iguanea is popularly used in the treatment of diabetes mellitus. Therefore, hypercholesterolemic rats (1% cholesterol) were orally treated with CI extract (C-150, CI-300, or CI-600 mg/kg) or Simvastatin (4 mg/kg) (n = 6) once a day (30 days) with a hypercholesterolemic diet.
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Selon ZANCHET B (2018)
D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.
Évolution de cette fiche publique
Sous le CTA · journal des mises à jour
+2 indications · ~2 indications corrigées · −4 indications · +10 références · ~2 références corrigées
Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.
+10 références — afficher les textes
TREVISAN RR et al, Avalaçào da atividade fitotoxica com enfoque alelopático do extracto das cascas de Celtis Iguanea (Jacq) Sargent Ulmaceae e purificaçao de doist triterpènes, Rev Bras Plant Med, 14:494-9, 2012-
AjoutéePaula, M.A et al, Caracterização Farmacognóstica Da Celtis iguanaea (Jacq.) Sargent. Lat. Am. Jl. Pharm. 29, 526–33. 2010-Abstract: Pharmacognostic characterization of Celtis iguanaea (Jacq.) Sargent.” Celtis iguanaea (Jacq.) Sar- gent (Ulmaceae) is popularly known as esporão-de-galo & widely used in Brazilian folk medicine. The aim of this work was to perform a pharmacognostic study of C. iguanaea leaves & young stem through macro a microscopic analysis as well as phytochemical screening, purity essays (moisture, total & acid insoluble ash con- tents), total polyphenols & total flavonoids…
AjoutéeZanchet B et al,. In-Vitro Antiproliferative Potential of Celtis iguanaea Against Ovarian (OVCAR-3) & Colon (HT-29) Tumor Cell. Eur. Jl. Med. Plants, 1 :9, 2019--Abstract : The species Celtis iguanaea (Jacq.) Sarg., (Cannabaceae) is widely distributed in Brazil where it is known as “esporão-de-galo or taleira”. The leaves are popularly used as anti-inflammatory, in the treatment of body pain & urinary infections. However, the antiproliferative potential against human cancer cells remain to be elucidated. In this study, extracts & different fractions from the leaves of CI were tested in vi…
AjoutéeAlmeida D.D.S et al. Antinociceptive, Anti-Inflammatory, & Antioxidant Effects of a Flavonoid-Rich Phytocomplexfrom the Leaves of Celtis iguanaea (Jacq.) Sargent (Cannabaceae). Nat. Prod. Res. 2024-Abstract : We demonstrated the antinociceptive & anti-inflammatory effects of the ethyl acetate leaf extract of Celtis iguanaea (Jacq.) Sargent (EEAc) in mice. The in vitro antioxidant activity of EAECi & its phytoconstituents was also investigated. The antinociceptive effect of EAECi is attributed to its anti-inflammatory activity, as evidenced by its anti-hyperalgesic & antiedematogenic effects.…
AjoutéeSAMADD A et al, A comprehensive account on ethnobotany, phytochemistry & pharmacological insights of genus Celtis, Heliyon, 10(9): e29707., 2024-Abstract: The plants of Celtis L. genus have been traditionally used to cure aches, sore throats, fevers, cancer, sexually transmitted diseases, sexual weakness, diarrhea, stomach problems, amenorrhea, menstrual disorders, kidney stones, & pain. The review aims to give a comprehensive account of the current state of ethnopharmacology, phytochemistry, & biological activities of the Celtis genus, as well as to describe the potential area of future av…
AjoutéeBellard e Silva R et al, quality-by-design Development of Celtis iguanaea Microparticles with In vivo Gastroprotective Efficacy, Rev Braz de Farmacogn, 35 :4, 2025-Abstract: A spray-dried hydroethanolic leaf extract of Celtis iguanaea (Jacq.) Sarg., Cannabaceae, was developed & evaluated for its gastroprotective efficacy in mice. A 3 3 Box-Behnken design (n = 15) and Response Surface Methodology were used to optimize the spray drying. The variables studied were drying air inlet temperature (100-140 °C), extract feed flow rate (0.3-0.7 l/h), & leucine content (15-45% m/m relative to solids) …
AjoutéeGONZALVES NZ et al, toxicidade oral aguda do extrato de folhas de Celtis iguanea (Jacq) Sargent em ratos & camundongos, Rev Bras Plantas Med, 17:1118-24, 2015-Abstract:
AjoutéeRIBEIRO KR et al, Spray-Dried Celtis iguanaea (Jacq.) Planch (Cannabaceae) Extract: Building Evidence for Its Therapeutic Potential in Pain & Inflammation Management, Plants, 14(13):2008, 2025-Abstract: Celtis iguanaea, widely used in Brazilian folk medicine, is known for its analgesic & anti-inflammatory properties. This study evaluated the in vitro antioxidant capacity & the in vivo antinociceptive & anti-inflammatory mechanisms of the standardized spray-dried Celtis iguanaea hydroethanolic leaf extract (SDCi). Phytochemical analysis showed that SDCi contains 21.78 ± 0.82 mg/g polyphenols…
AjoutéeRODRIGUEZ-Martins JL et al. Efeito Anti-Ulcerogênico e Antisecretório do Extrato Hexânico das Folhas de Celtis iguanaea (Jacq.) Sargent. Rev. Bras. Plantas Med. 16, 250–5. 2014-
AjoutéeRIBEIRO KR et al, Alternative Model-Based Safety Assessment of a Celtis iguanaea Standardized Spray-Dried Extract, Rev Brasil de Farmacogn, 2026-Abstract: The Celtis iguanaea (Jacq.) Sarg., Cannabaceae, standardized spray-dried extract, underwent acute safety evaluation using a range of alternative toxicological models in alignment with Organization for Economic Co-operation & Development Test Guidelines. Acute aquatic toxicity was assessed using the Artemia salina lethality test (LC 50 418.4 μg/ml) & the zebrafish (Danio rerio) embryo toxicity test (OECD TG 236; LC 50 1116.0 μg/ml). Accord…
AjoutéeTREVISAN RR et al, Avalaçào da atividade fitotoxica com enfoque alelopático do extracto das cascas de Celtis Iguanea (Jacq) Sargent Ulmaceae e purificaçao de doist triterpènes, Rev Bras Plant Med, 14:494-9, 2012-
CorrigéeRODRIGUEZ-Martins JL et al. Efeito Anti-Ulcerogênico e Antisecretório do Extrato Hexânico das Folhas de Celtis iguanaea (Jacq.) Sargent. Rev. Bras. Plantas Med. 16, 250–5. 2014-
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