Chamaesyce hirta (Malonmen) : vertus médicinales en extraction alcoolique

Chamaesyce hirta (Malonmen, Mal-nommée) — famille Euphorbiacées.

Synonymes scientifiques : Euphorbia hirta-L, Euphorbia pilulifera-L.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 30 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 85 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Normalisation des paramètres sériques (SGPT, SGOT, ALP, Bilirubine), notamment à la suite d‘une chimiotherapie antituberculeuse

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon DUBEY S (2014)

     Extrait Alteration in the levels of biochemical markers of hepatic damage like SGPT, SGOT, ALP, Bilirubin, were tested in both treated and untreated groups. Carbon tétra chloride (2 ml/kg) has enhanced the SGPT, SGOT, ALP, Bilirubin.

   • Selon SENNIAPPAN P (2024)

     Extrait Objective: The study aimed to determine the antiulcer and hepatoprotective activities of Euphorbia hirta petroleum ether, chloroform and ethanolic extracts on paracetamol-induced ulcerated Wistar rats. A significant (p < 0.001) reduction in SGPT, SGOT, ALP, DB & TB levels in the EEEH 400 mg/kg extract-treated group was observed compared to the paracetamol group.

   • Selon OGEYEMHE BE (2026)

     Extrait The results showed no statistically significant differences (p > 0.05) in serum liver enzyme activities or bilirubin concentrations between treated groups & the control. Serum activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, & bilirubin levels were determined using standard biochemical methods.

   • Selon Apostol JG (2012)

     Extrait hirta decoction prepared by boiling the fresh entire plant in distilled water for 15 minutes was lyophilized and the resulting solid was dissolved in distilled water & used to determine total phenolics and to prepare stock solutions administered to thrombocytopenic rats. The antithrombocytopenic effect of the solution of the lyophilized decoction of Euphorbia hirta was investigated in Sprague-Dawley rats with subnormal platelet counts induced by ethanol.

   • Selon Tuhin RH (2017)

     Extrait hirta was subjected to determine the total phenolic content and total flavonoid content using galic acid and quercetin, respectively as standard. hirta is famous for its medicinal importance among the tribal population.

2. 2

   Hépatite, cirrhose, stéatose hépatique

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon DUBEY S (2014)

     Extrait Ethanolic extract of Euphorbia hirta Linn was prepared and tested for its hepatoprotective effect against CCl4induced hepatitis in rats. Treatment with Ethanolic extract of Euphorbia hirta Linn (100 mg/kg and 300 mg/kg) has brought back the altered levels of biochemical markers to the near normal levels in the dose dependent manner.

   • Selon SENNIAPPAN P (2024)

     Extrait Objective: The study aimed to determine the antiulcer and hepatoprotective activities of Euphorbia hirta petroleum ether, chloroform and ethanolic extracts on paracetamol-induced ulcerated Wistar rats. The air-dried whole plant was crushed, & 500 g of the powder & petroleum ether, chloroform & ethanol were used for continuous extraction by the Soxhlet device.

   • Selon Apostol JG (2012)

     Extrait hirta decoction prepared by boiling the fresh entire plant in distilled water for 15 minutes was lyophilized and the resulting solid was dissolved in distilled water & used to determine total phenolics and to prepare stock solutions administered to thrombocytopenic rats. The antithrombocytopenic effect of the solution of the lyophilized decoction of Euphorbia hirta was investigated in Sprague-Dawley rats with subnormal platelet counts induced by ethanol.

   • Selon OGEYEMHE BE (2026)

     Extrait A subacute experimental study was conducted to evaluate the short-term hepatic effects of aqueous Euphorbia hirta extract in adult male albino rats. These findings indicate that short-term oral administration of aqueous EH extract at the tested doses does not induce biochemical or histopathological evidence of liver injury.

   • Selon Tuhin RH (2017)

     Extrait hirta was subjected to determine the total phenolic content and total flavonoid content using galic acid and quercetin, respectively as standard. hirta is famous for its medicinal importance among the tribal population.

3. 3

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Maurya AK (2012)

     Extrait The present study was aimed to evaluate the antidiabetic activity potential of Euphorbia hirta leaves against streptozotocin (STZ) induced experimental rats. An ethanolic extract of E hirta was found to reduce blood sugar in streptozotocin induced diabetic rats.

   • Selon Shwetha S (2023)

     Extrait Conclusion: The results of the presents investigation recommends that, one of the mechanisms of ETOH extract of EH for antidiabetic activity is reduction of insulin resistance. The objective of current investigation was to assess the mechanism of action of Euphorbia hirta for its antidiabetic properties.

   • Selon Tuhin RH (2017)

     Extrait A single injection of alloxan monohydrate (120 mg/kg, i.p.) prepared in normal saline was administered to produce diabetes in rats, after overnight fasting. The aim of present work was to evaluate the wound healing property in diabetic animals by oral and topical administration of ethanolic extract of E.

   • Selon Sharma A (2025)

     Extrait Euphorbia hirta Linn is a widely recognized medicinal herb utilized in traditional medicine systems for treating respiratory ailments, gastrointestinal disorders, skin conditions, & wounds. Experimental studies have demonstrated a range of pharmacological effects, such as antimicrobial, anti-inflammatory, antioxidant, antidiabetic, anticancer, wound-healing properties.

   • Selon Bachhhar V (2024)

     Extrait Further antioxidant (DPPH & Phosphomolybdate assay) & antidiabetic activity were evaluated with the IC50 value of 39.01 ± 0.56, 48.29 ± 0.69, & 55 ± 1.69 µg/ml, respectively, which indicated the potency of the synthesized nanoparticles for various biomedical & pharmacological applications. In this study, titanium dioxide nanoparticles(TiO2 NPs) have been synthesized by ultrasonication-assisted cold maceration green technique mediated through stem extract of Euphorbia hirta such that the plant's phytochemical constituents are preserved & do not deteriorate.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.