Cinnamonum verum (Kannèl) : vertus médicinales en extraction alcoolique

Cinnamonum verum (Kannèl, cannelle, Cinnamon) — famille Lauracées.

Synonymes scientifiques : Cinnamomum Zeylanicum-Breyne, C zeylanicum Blume, Laurus Cinnamomum-Linn.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 22 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 112 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabete mellitus de type II

   Partie usitée : Écorce.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ishaq BM (2022)

     Extrait Group 1 acts as a normal control, Group 2 as a diabetic control, & Group 3 as a standard control, all animals of Group 3 were given Glibenclamide at a dose of 5 mg/kg p. Streptozotocin (60 mg/kg, i.p.) was used to induce diabetes.

   • Selon Mishra A (2010)

     Extrait The current study was designed to evaluate the ameliorative effect of the Cinnamon oil upon early-stage diabetic nephropathy owing to its antioxidant & antidiabetic effect. Early stage of diabetic nephropathy was induced by administration of alloxan (150 mg/kg, I.

   • Selon Gulcin I (2019)

     Extrait Ethanolic (EEC) & aqueous (WEC) extracts of Cinnamomum verum were evaluated for their antioxidant profiles by eight distinguished bioanalytical antioxidant methods. As a conclusion, both EEC & WEC had rich phenolic contents & demonstrated effective anticholinergic, antidiabetic & antioxidant effects.

   • Selon Joshi K (2010)

     Extrait Cinnamomum zeylanicum, a commonly used spice and well-known medicinal plant has been reported to have anti-diabetic, anti-oxidant & anti-microbial properties.

   • Selon Verspohl E J (2005)

     Extrait Rats were given Cinnamomum cassia bark or extracts from Cinnamomum cassia & zeylanicum to evaluate blood glucose & plasma insulin levels in rats under various conditions. The elevation in plasma insulin was direct since a stimulatory in vitro effect of insulin release from INS-1 cells (an insulin secreting cell line) was observed.

2. 2

   Cancer : traitement adjuvant du carcinome : formulation ayurvédique: Kanchan GUGULLU

   Partie usitée : Écorce.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Varadarajan S (2020)

     Extrait Clinical significance: The anticancer properties of CV could be explored further for prevention & management of oral squamous cell carcinoma. Conclusion: CV its active compounds exhibited in vitro anticancer effects on oral squamous cell carcinoma.

   • Selon Husain L (2018)

     Extrait Conclusion: Ethanolic bark extract of CZ could be potentially beneficial in treating breast cancer & may be of interest for future studies in developing integrative cancer therapy against proliferation, metastasis, & migration of breast cancer cells. Aim of the study: In the present study, apoptotic & anti-microbial activity of ethanolic extract of CZ was evaluated against human breast cancer cell line MDA-MB-231 & compared for its effect on normal kidney epithelial cell line Vero.

   • Selon KUBATKA P (2020)

     Extrait Assessment of epigenetic changes in rat tumor cells in vivo showed a significant decrease in lysine methylation status of H3K4m3 & H3K9m3 in the high-dose treated group, a dose-dependent increase in H4K16ac levels (H4K20m3 was not changed), down-regulations of miR21 & miR155 in low-dose cinnamon groups (miR22 & miR34a were not modulated), & significant reduction of the methylation status of two out of five gene promoters ATM & TIMP3 (PITX2, RASSF1, PTEN promoters were not changed). Comprehensive oncology research suggests an important role of phytochemicals or whole plant foods in the modulation of signaling pathways associated with anticancer action.

   • Selon Qabaha K (2017)

     Extrait The objective of this work is to evaluate the in vitro inhibitory effect of C longa & Cinnamon ethanolic extracts on Lipopolysaccharide (LPS)-induced Interlukin-6 (IL-6) & Tumor Necrosis Factor-α (TNF-α) by polymorphonuclear Cells (PMNCs).

   • Selon Usha M (2012)

     Extrait The in vitro antibacterial activities of two spices cinnamon bark (Cinnamonum zeylanicum) and Ajowan fruits (Trachyspermum ammi) ethanol & acetone extracts has been evaluated against two-gram negative food spoilage bacteria Pseudomonas sp., Escherichia coli & two-gram positive bacteria Bacillus subtilis & Staphylococcus aureus. The results obtained in the present study suggest that the ethanol extract of Czeylanicum & T ammi revealed a significant scope to develop a novel broad spectrum of antibacterial herbal formulation & can be used for cooked food preservation,.

3. 3

   Douleur, hyperalgie

   Partie usitée : Feuille. Profil pharmacologique documenté : Diclofenac-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Qabaha K (2017)

     Extrait Curcuma longa & Cinnamon are used in folkloric medicine & thought to have different pharmacological activities including anti-inflammatory effects. The observed anti-inflammatory effect may be due to the presence of curcuminoids & cinnamic acid from C longa & Cinnamon, respectively.

   • Selon Klinthong S (2015)

     Extrait The crude ethanol extract in various concentrations (25, 50, 100 mg/kg) were tested for anti-inflammatory activity in cotton pellet-induced granuloma in rats. It was found that the extract of the RSDM formula at 50 mg/kg, per oral, showed significant inhibitory effect (p < 0.05) on granuloma formation comparable to indomethacin, a standard non-steroidal antiinflammatory drug (5 mg/kg).

   • Selon Pandey M (2015)

     Extrait In the present study, ethanol & aqueous extracts of leaf galls of Cinnamomum verum were prepared to evaluate the antioxidant activity using 2, 2-diphenyl-1-picrylhydrazyl free radical scavenging assay and superoxide radical scavenging assay with ascorbic acid as a standard, and analgesic activity by tail immersion test & acetic acid-induced writhing test methods using diclofenac sodium as the reference drug. For analgesic activity, ethanol extract showed the maximum time required for response against thermal stimuli (6.75±0.47 s) & maximum % of writhing inhibition (44.57%) when compared to aqueous extract (5.25±0.48 s & 32.61%), whereas diclofenac showed response in 7.25±0.25 s 67.39% inhibition in tail immersion & writhing tests, respectively.

   • Selon Khan MS (2011)

     Extrait This study was aimed to evaluate effects of certain essential oils namely Cinnamomum verum, Syzygium aromaticum, Cymbopogon citratus, C martini & their major components cinnamaldehyde, eugenol, citral & geraniol respectively, on growth, hyphal ultrastructure & virulence factors of Aspergillus fumigatus & Trichophyton rubrum. Our findings highlight anti-elastase & anti-keratinase activity of above-mentioned essential oils as a novel property to be exploited in controlling invasive & superficial mycoses.

   • Selon Alibi S (2020)

     Extrait The antimicrobial, anti-biofilm, anti-quorum sensing, & anti-oxidant activities of four essential oils extracted from Cinnamomum verum, Origanum majorana, Thymus vulgaris, & Eugenia caryophyllata against Gram-positive & Gram-negative multidrug-resistant bacteria were evaluated in vitro. These EOs have a remarkable anti-biofilm & anti-quorum sensing activities against almost all the species studied.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.