Citrus maxima (Chadèk) : vertus médicinales en extraction alcoolique

Citrus maxima (Chadèk, Pomelos) — famille Rutacées.

Synonymes scientifiques : Aurantium decumana-(L.)-Mill, A maximum-Burm., Citrus costata-Raf., C grandis -(L.) Osbeck, C pompelnos-Risso, C sabon-Siebold ex Hayata, C yamabuki -Yu. Tanaka.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 26 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 144 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant : du carcinome hépatique & mammaire

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Da Silva ES (2018)

     Extrait As several varieties of citrus are known to possess antioxidant & cancer chemopreventive properties, the aim of the study was to evaluate in vitro if this CM possess these properties. Toranja ‘Burarama’, Citrus maxima (Burm.) Merr.

   • Selon Feksa DL (2018)

     Extrait Non-alcoholic fatty liver disease is a spectrum of liver changes, ranging from hepatic steatosis to hepatocellular carcinoma. The objective of this study was to evaluate the n vitro antioxidant potential of the CM leaves extract & on Wistar rats submitted to hepatic steatosis induction by fructose-associated hyperlipid diet (FHD).

   • Selon Riaz M (2015)

     Extrait Citrus maxima peel is rich in natural phenolic compounds & has a long use in the traditional medicine. In addition, lipid peroxidation products (MDA), nitric oxide, advanced protein oxidation products level (APOP), & catalase activities were also analyzed along with the histological profiling for the inflammatory cell infiltration, collagen, & iron deposition in liver.

   • Selon Nakamura M (2019)

     Extrait Citrus grandis Osbeck has been as a remedy for liver damage & hang over.

   • Selon LIN CY (2022)

     Extrait The aim of this study was to explore the lipid-lowering effects of nobiletin & the underlying molecular mechanisms in vitro in hepatic cells & in vivo in zebrafish models. Nobiletin significantly inhibited ANGPTL3 promoter activity & attenuated the transcription factor liver X receptor-α (LXRα)-mediated ANGPTL3 transcription.

2. 2

   Diabète mellitus de type II,

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Reshmi SK (2099)

     Extrait The aim of this study was to identify the bioactive compound of Citrus maxima fruit that targets the enzymes responsible for hyperglycaemia. Further application, such as developing food formulations from CM will benefit diabetic populations. (2018) — extrait : Citrus maxima belongs to the genus Citrus of the family Rutaceae, an important fruit with great benefits for humans in the world. Diabetes was induced by intraperitoneal injection of a single dose of Streptozotocin (STZ) 65 mg\kg body weight.

   • Selon Mohammed SM (2021)

     Extrait The ethanol extract of Citrus maxima fruit peel was evaluated for its hypoglycaemic and hypolipidemic activity in normal and Streptozotocin (STZ)-induced diabetic rats, using fasting & glucose tolerance test measurements. Results showed that CM extract possesses significant antidiabetic activity against streptozotocin induced diabetic rats by decreasing blood glucose levels, maintaining body weight, & serum lipid concentrations to approximate normal level.

   • Selon Abdul Muneer MT (2014)

     Extrait citrus maxima have been recommended in traditional herbal medicine as the source of diabetic medication or remedy for diabetes. In view of the various effects of CM, this study was designed to assess the effect of CM stem bark on alloxan induced streptozotocin-induced type – II diabetic rats & glucose tolerance test,.

   • Selon Mangesh, K (2014)

     Extrait Animals will be randomly divided into 5 groups of 6 each & assigned as Group 1: Normal control (normal saline), Group 2: Diabetic control (Streptozotocin 65 mg/Kg), Group 3: Diabetic Citrus maxima (200 mg/Kg), Group 4: Diabetic Anvillea garcinii (300 mg/Kg), Group 5: Diabetic Glibenclamide (500 mcg/Kg). This study was designed to assess the effect of ethanolic extract of fruit peels of Citrus maxima & ethanolic extract of dried whole plant of Anvillea garcinii on streptozotocin-induced diabetic rats & glucose tolerance test.

3. 3

   Diabète mellitus de type II

   Partie usitée : Fruit. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Reshmi SK (2099)

     Extrait The aim of this study was to identify the bioactive compound of Citrus maxima fruit that targets the enzymes responsible for hyperglycaemia. Further application, such as developing food formulations from CM will benefit diabetic populations. (2018) — extrait : Citrus maxima belongs to the genus Citrus of the family Rutaceae, an important fruit with great benefits for humans in the world. Diabetes was induced by intraperitoneal injection of a single dose of Streptozotocin (STZ) 65 mg\kg body weight.

   • Selon Mohammed SM (2021)

     Extrait The ethanol extract of Citrus maxima fruit peel was evaluated for its hypoglycaemic and hypolipidemic activity in normal and Streptozotocin (STZ)-induced diabetic rats, using fasting & glucose tolerance test measurements. Results showed that CM extract possesses significant antidiabetic activity against streptozotocin induced diabetic rats by decreasing blood glucose levels, maintaining body weight, & serum lipid concentrations to approximate normal level.

   • Selon Abdul Muneer MT (2014)

     Extrait citrus maxima have been recommended in traditional herbal medicine as the source of diabetic medication or remedy for diabetes. In view of the various effects of CM, this study was designed to assess the effect of CM stem bark on alloxan induced streptozotocin-induced type – II diabetic rats & glucose tolerance test,.

   • Selon Mangesh, K (2014)

     Extrait Animals will be randomly divided into 5 groups of 6 each & assigned as Group 1: Normal control (normal saline), Group 2: Diabetic control (Streptozotocin 65 mg/Kg), Group 3: Diabetic Citrus maxima (200 mg/Kg), Group 4: Diabetic Anvillea garcinii (300 mg/Kg), Group 5: Diabetic Glibenclamide (500 mcg/Kg). This study was designed to assess the effect of ethanolic extract of fruit peels of Citrus maxima & ethanolic extract of dried whole plant of Anvillea garcinii on streptozotocin-induced diabetic rats & glucose tolerance test.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.