Cleome rutidosperma (Mouzanmbé blan) : vertus médicinales en extraction alcoolique

Cleome rutidosperma (Mouzanmbé blan, Ti Mouzanmbé ranpan, Ti kaya blan, Petit Mouzambé Blanc, Mouzambé rampant, petit Acaya blanc, White Mouzanmbé, Crawling Mouzanmbé, White Acaya, Little White Mouzambé, Crawling Mouzambé, Little White Acaya) — famille Capparacées.

Synonymes scientifiques : Cleome ciliata Schumach. & Thonn., C guineensis-Hook I, C thyrisiflora-De Wild & TD, Sieruela rutidosperma –(DC.) Roalson & J. C. Hall.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 44 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Racine.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Mondal S (2009)

     Extrait In the present study, the ethanolic extract of the roots of Cleome rutidosperma was tested for hypoglycaemic activity in normoglycaemic & alloxan induced hyperglycaemic rats at doses levels of 200 & 400 mg/kg p.o respectively. The study revealed that the root extract of CR caused significant reduction in the blood glucose level in both normoglycaemic & alloxan induced diabetic rats at the tested dose levels in a dose dependant manner.

   • Selon Okoro IO (2014)

     Extrait The present study was carried out to investigate the effects of oral administration of aqueous extracts of Cleome rutidosperma leaves & Senecio biafrae roots on blood glucose, biochemical parameters, lipid profile, antioxidant enzymes activity & hepatic glucose regulating enzyme activities in Streptozotocin (STZ)-induced diabetic rats. The aqueous extract of both plants at different doses (125mg/Kg, 250mg/Kg & 500mg/Kg) administered orally to the diabetic rats for 28 days, produced significant (p < 0.05) decrease in the level of blood glucose, feed & water intake as well as serum cholesterol, triacylglycerols, low density lipoprotein (LDL), creatinine, urea, bilirubin & activity of liver marker enzymes such as AST, ALT, ALP & TBARS in liver and kidney.

   • Selon Oridupa OA (2017)

     Extrait The hypoglycaemic & antihyperglycaemic effects of methanol extract of leaves of Cleome rutidosperma (Cr) DC (Family: Capparidaceae) was investigated in Wistar rats. Fasting blood glucose levels (FBGL) were determined & alloxan-treated rats with BGL >200 mg/dl 48 h post-induction were considered diabetic.

   • Selon Okoro I (2014)

     Extrait the present study aimed to investigate the acute antihyperglycemic effects of four different solvent extracts (Petroleum ether, acetone, absolute ethanol & water) of two plants: Cleome rutidosperma (leaves) & Senecio biafrae (root) in STZ-induced diabetic mice & their in vitro antioxidant activities as well as their phytoconstituents. All extracts as well as the standard drug, glibenclamide (at 600 μg/kg body weight) significantly lowered blood glucose level (p<0.05) of the diabetic mice by 28.784±15.46-40.866±15.61% for CR & 10.652±6.36-19.858±7.65% for Senecio biafrae within 6 hrs of extracts administration.

   • Selon Khuntia A (2022)

     Extrait By centralizing medical data provided by the scientific literature, we offer in the present work a comprehensive perspective on a wide range of bioactive compounds identified from diverse Cleome species, emphasizing the correlation of natural active substances with potential pharmacological activities that can contribute to the improvement of therapeutic management for a range of pathologies. The potential biological actions & pharmacological effects, such as analgesic, anti-inflammatory, antipyretic, anti-diabetic, antidepressant, antibacterial, anti-arthritic, anticancer, & hepatoprotective are closely related to the active substances contained in various parts of the plants.

2. 2

   Douleur : hyperalgie, fièvre

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Bose A (2007)

     Extrait Oral administration of the ethanolic extract (200 a&400 mg/kg, p.o) & its fractions (200 mg/kg each) of the aerial parts of Cleome rutidosperma produced significant analgesic activity in acetic acid-induced writhing & tail immersion tests, anti-inflammatory effect against carrageenin induced inflammation & adjuvant induced polyarthritis & antipyretic activity against yeast-induced pyrexia.

   • Selon Khuntia A (2022)

     Extrait The potential biological actions & pharmacological effects, such as analgesic, anti-inflammatory, antipyretic, anti-diabetic, antidepressant, antibacterial, anti-arthritic, anticancer, & hepatoprotective are closely related to the active substances contained in various parts of the plants. By centralizing medical data provided by the scientific literature, we offer in the present work a comprehensive perspective on a wide range of bioactive compounds identified from diverse Cleome species, emphasizing the correlation of natural active substances with potential pharmacological activities that can contribute to the improvement of therapeutic management for a range of pathologies.

   • Selon Mondal (2009)

     Extrait Mondal et al, Analgesic, anti-inflammatory & antipyretic studies of Cleome rutidosperma DC.

   • Selon Ansari P (2016)

     Extrait rutidosperma is used in folk medicine for diuretic, laxative, analgesic, anti-inflammatory, antipyretic, antimicrobial, anti-oxidant, hypoglycemic, & anthelmintic activities. Methods: Thermal method (hot plate test & tail flick test) was induced to judge the anti-inflammatory effect & couple of chemical method also used (formalin induced licking test; writhing test carried by acetic acid) to evaluate analgesic effect.

   • Selon BOSE A (2004)

     Extrait BOSE A et al, Analgesic & locomotor activity of extracts of Cleome rutidosperma DC, Indian j of Pharmaceut Sci, 66 (6):795-7, 2004,.

3. 3

   Infection fongique : Aspergillus niger, Penicillium notatum, Candida albicans, Helminthosporium solani

   Partie usitée : Parties aériennes. Profil pharmacologique documenté : Clotrimazole-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Morah F (2018)

     Extrait The oil exhibited antimicrobial activity against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Streptococcus faecalis, Candida albicans & Aspergillus niger. Cleome rutidosperma is extensively employed in herbal medicine.

   • Selon Knunta A (2011)

     Extrait The extracts were vacuum dried & studied for in vitro antifungal activity against Aspergillus niger, Penicillium notatum, Candida albicans, Helminthosporium solani. However thorough literature survey indicated that different plants of the same genus available in tropical parts of India have various reported biological activities like antifungal activity, antibacterial activity.

   • Selon Morah F (2018)

     Extrait To determine the chemical constituents, antimicrobial & anthelmintic activities of chloroform fraction of the ethanol extract of the aerial part of Cleome rutidosperma. The antimicrobial sensitivity test was carried out using agar disc diffusion method while broth dilution method was used to determine the minimum inhibitory, minimum bactericidal & minimum fungicidal concentrations.

   • Selon Ragavan MR (2018)

     Extrait The present study was aimed to analyze the phytochemicals of leaf extracts of Cleome rutidosperma & to check their antioxidant, antimicrobial & anticancer activities using in vitro methods. Antibacterial activity of the prepared extracts was performed against Bacillus cereus, Staphylococcus aureus, Escherichia coli & Salmonella typhi.

   • Selon Khuntia A (2022)

     Extrait By centralizing medical data provided by the scientific literature, we offer in the present work a comprehensive perspective on a wide range of bioactive compounds identified from diverse Cleome species, emphasizing the correlation of natural active substances with potential pharmacological activities that can contribute to the improvement of therapeutic management for a range of pathologies. The potential biological actions & pharmacological effects, such as analgesic, anti-inflammatory, antipyretic, anti-diabetic, antidepressant, antibacterial, anti-arthritic, anticancer, & hepatoprotective are closely related to the active substances contained in various parts of the plants.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.