Cleome spinosa (Gwo Mouzanmbé) : vertus médicinales en extraction alcoolique

Cleome spinosa (Gwo Mouzanmbé, Gwo kaya, Mouzanmbé sis fèy, moustach-chat, Gros Mouzambé, Gros Acaya, Mouzambé-à-six feuilles, Moustache-à-chat, cat’s moustache, Big Acaya, Six-leaved Mouzambé, Cat’s-whisker) — famille Capparacées.

Synonymes scientifiques : Cleome heptaphylla L., C pubescens Sims, Neocleome spinosa (Jacq.) Small, C spinosa-SW, C tonduzii-Briq, Tarenaya spinosa (Jacq.) Raf.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 11 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 21 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome hépatique, mammaire & prostatique

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Abkari (2015)

     Extrait This study aimed to evaluate the effects of (CS) fruit extract on NASH compared to fenofibrate & explored the related molecular mechanism.Results: In the rats (n = 40) model of NASH, biochemical and histopathological examinations showed that liver steatosis, inflammation, & hepatic fibrosis were markedly attenuated in response to CS & fenofibrate interventions. In conclusion, CS has favorable therapeutic effects for NASH, which was associated with ameliorating steatosis & fibrosis via regulation of the DNL & β-oxidation pathway genes.

   • Selon Jayaprakash AP (2016)

     Extrait In this present context, one traditional medicinal plant namely Cleome viscosa was selected & its antioxidant effect by DPPH, ABTS & Nitric oxide scavenging assay methods, cytotoxic & in vitro anticancer effects in different fractions of solvent were evaluated phyto-constituents.The results of studies show that the plant has good antioxidant activity low cytotoxic effect & good anticancer properties. viscosa has less cytotoxic activity compared to other extracts & also Cleome viscose whole plant ethyl acetate fraction showed potent toxicity with CTC50 of 130.00±8.66 µg/ml.

   • Selon McNeil MJ (2010)

     Extrait Five different essential oil extractions of the aerial parts of Cleome spinosa Jacq were examined. The oils obtained by hydrodistillation of the whole aerial parts, aerial parts without flowers (fruit, leaves and stem), flowers, fruits & leaves have been examined by GC-FID and GC-MS.

2. 2

   Infection bactérienne : Escherichia coli, Staphylococcus aureus & Pseudomonas aeruginosa

   Partie usitée : Feuille. Profil pharmacologique documenté : Imipenem-like, Gentamycine-like, Norfloxacine-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon da Silva APS (2016)

     Extrait Additionally, antimicrobial & combinatory effects with oxacillin were assessed against eight clinical isolates of Staphylococcus aureus. aureus & their phenolic (r = −0.89) & flavonoid content (r = −0.87), reinforcing the possible role of these metabolite classes on the antimicrobial activity of CS derived extracts.

   • Selon Muniz Dos-Santos FM (2019)

     Extrait Methods: The bacterial Escherichia coli, Staphylococcus aureus & Pseudomonas aeruginosa strains, grown in Heart Agar Infusion, were tested. To evaluate the antibacterial activity & neuroprotective capacity of the ethanolic & aqueous extracts of Tarenaya spinosa as well as to determine & quantify some of its polyphenols by high performance liquid chromatography with diode-array detection (HPLC-DAD).

   • Selon Sant' Anna da Silva A (2016)

     Extrait Due to the use of Cleome spinosa in traditional medicine against inflammatory & infectious processes, this study evaluated the in vitro antimicrobial potential & phytochemical composition of extracts from its roots & leaves. Additionally, antimicrobial & combinatory effects with oxacillin were assessed against eight clinical isolates of Staphylococcus aureus.

   • Selon da Silva APS (2016)

     Extrait Due to the use of Cleome spinosa in traditional medicine against inflammatory & infectious processes, this study evaluated the in vitro antimicrobial potential & phytochemical composition of extracts from its roots & leaves. Additionally, antimicrobial & combinatory effects with oxacillin were assessed against eight clinical isolates of Staphylococcus aureus.

   • Selon Santos DA (2005)

     Extrait Considering these indications and using pharmacological methodologies, this study evaluated the antinociceptive and anti-inflammatory potential of the methanolic extract from aerial parts of Cleome spinosa (EMCS) & flavonoids compounds F10-16 & F11-13, orally administered, and the mechanisms of action involved. Some flavonoids showed anti-oxidant, antifungal, antibacterial, antimutagenic & anti-spasmodic activity.

3. 3

   Infection fongique : Candida albicans, C Krusei & C Tropicalis

   Partie usitée : Feuille. Association synergique mentionnée : Fluconazole.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon da Silva APS (2016)

     Extrait spinosa different extracts were obtained (cyclohexane: ChL & ChR; chloroform: CL & CR; ethyl acetate: EAL & EAR, methanol: ML & MR). The antimicrobial activity was evaluated by the broth microdilution method to obtain the minimum inhibitory (MIC) & microbicidal (MMC) concentrations against 17 species, including bacteria & yeasts.

   • Selon Rodriguez FC (2019)

     Extrait The IC50 results demonstrated that the combination of the extracts with fluconazole were more significant than the products tested alone, with values from 4.9 to 34.8 μg/mL for the ethanolic extract/fluconazole & 5 to 84.7 μg/mL for the aqueous extract/fluconazole. The effect of the combination extract/fluconazole was verified by microdilution, with the extracts in subinhibitory concentrations (MFC/16).

   • Selon McNeil MJ (2010)

     Extrait spinosa found in Jamaica & the in vitro antioxidant, insecticidal & antimicrobial potential of the oil from the aerial parts. Five different essential oil extractions of the aerial parts of Cleome spinosa Jacq were examined.

   • Selon Sant' Anna da Silva A (2016)

     Extrait Due to the use of Cleome spinosa in traditional medicine against inflammatory & infectious processes, this study evaluated the in vitro antimicrobial potential & phytochemical composition of extracts from its roots & leaves. The antimicrobial activity was evaluated by the broth microdilution method to obtain the minimum inhibitory (MIC) & microbicidal (MMC) concentrations against 17 species, including bacteria & yeasts.

   • Selon Muniz Dos-Santos FM (2019)

     Extrait To evaluate the antibacterial activity & neuroprotective capacity of the ethanolic & aqueous extracts of Tarenaya spinosa as well as to determine & quantify some of its polyphenols by high performance liquid chromatography with diode-array detection (HPLC-DAD). Conclusions: Although it does not present an antibacterial action, the extracts of TS can be used in the pharmaceutical industries since its extracts show modulating action of drugs.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.