Cleome viscosa (Ti-kaya jôn) : vertus médicinales en extraction alcoolique

Cleome viscosa (Ti-kaya jôn, Ti Mouzanmbé, Petit Acaya jaune, petit Mouzambé, Little yellow Acaya, little Mouzambé) — famille Capparacées.

Synonymes scientifiques : Cleome icosandra-L, Polanisia viscosa-(L)-DC, Polanisia icosandra-(L)-W & A.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 16 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 39 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Neuropathie diabétique, sciatique

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Rao BS (2014)

     Extrait In the present study, we investigated the neuroprotective effect of ethanolic extract of Cleome viscosa (EECV) against streptozotocin (STZ) induced diabetic neuropathy in Wistar rats. Diabetic neuropathy (DN) is a secondary microvascular complication of diabetes causing damage to the nerves and is characterized by fall in nerve conduction velocity, severe pain, impaired sensation and degeneration of nerve fibres.

   • Selon Yarrappagaari S (2020)

     Extrait The current research is to develop an easy & eco-friendly method for the synthesis of three different concentrations of silver nanoparticles (1mMCvAgNPs, 2mMCvAgNPs & 3mMCvAgNPs) using aqueous whole plant extract of Cleome viscosa & to evaluate their antibacterial, antioxidant & antidiabetic properties. Hence, to validate our results, the in vivo studies at the molecular level are needed to develop CV as an antibacterial, antioxidant & anti-diabetic agent.

2. 2

   Detoxifiante hépatique, fibrose hépatique

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Kumar SV (2009)

     Extrait The liver weight that increased following CCl4 administration due to déposition of Collagen was reduced by the ethanolic extract C viscosa L. Liver fibrosis is the excessive accumulation of extracellular matrix proteins including Collagen that occurs in most types of chronic liver diseases.

   • Selon Nguyen TP (2017)

     Extrait At the concentration of 25 μM and 50 μM, 1 showed cytotoxic activity against HepG2 cells (cell viability was decreased to 22.2 & 23.0%, respectively, compared with doxorubicin control), while at the concentration of 100 μM, 1 showed hepatoprotective activity against CCl4-induced hepatotoxicity on HepG2 cells (34.3%, compared with quercetin control).-OJOGBANE et al, Acute toxicity & histopathological assessment of methanolic extract of Cleome viscosa Linn whole plant, Planta Medica, 80 :10, 2014.-Abstract : Cleome viscosa Linn (Cleomaceae) is a medicinal plant used widely in ethnomedicine. One new flavonol glycoside named visconoside C (1), together with seven known flavonol glycosides, quercetin 3-O-β-d-glucopyranoside 7-O-α-l-rhamnopyranoside (2), quercetin 7-O-α-l-rhamnopyranoside (3), astragalin (4), kaempferol 3-O-(4-O-acetyl)-α-l-rhamnopyranoside (5), kaempferol 7-O-α-l-rhamnopyranoside (6), kaempferitrin (7) and kaempferol 3-O-β-d-glucopyranoside 7-O-α-l-rhamnopyranoside (8) were isolated by various chromatography methods from the leaves of Cleome viscosa, Their structures were elucidated by IR, UV, HR-ESI-MS & NMR (1D & 2D) experiments.

   • Selon DAHIYA V (2014)

     Extrait Aim: This study was carried out to investigate the Chemopreventive effects of ethanolic extract of Cleome viscosa (EECV) on mutagenicity & hepatotoxicity caused by Benzo(a)Pyrène. Results: The activities of serum aminotransferases & the hepatic content of lipid peroxides were increased whereas liver antioxidants, such as glutathione (GSH), glutathione peroxidase (GPx), glutathione réductase (GR) were decreased in B(a)P-treatment group than control, but all these levels were significantly and dose dependently reversed by the treatment with EECV.

   • Selon Kumar Mobiya A (2010)

     Extrait In present study, Hepatoprotective activity of the ethanolic extract of Cleome Viscosa L. The hepatoprotective effect was evaluated on the basis of liver function parameters viz serum total Bilirubin, total protein, alanine transaminase, aspartate transaminase and alkaline phosphatase activities.

   • Selon Nguyen TP (2017)

     Extrait One new flavonol glycoside named visconoside C (1), together with seven known flavonol glycosides, quercetin 3-O-β-d-glucopyranoside 7-O-α-l-rhamnopyranoside (2), quercetin 7-O-α-l-rhamnopyranoside (3), astragalin (4), kaempferol 3-O-(4-O-acetyl)-α-l-rhamnopyranoside (5), kaempferol 7-O-α-l-rhamnopyranoside (6), kaempferitrin (7) & kaempferol 3-O-β-d-glucopyranoside 7-O-α-l-rhamnopyranoside (8) were isolated by various chromatography methods from the leaves of Cleome viscosa, Their structures were elucidated by IR, UV, HR-ESI-MS & NMR (1D & 2D) experiments. At the concentration of 25 μM and 50 μM, 1 showed cytotoxic activity against HepG2 cells (cell viability was decreased to 22.2 & 23.0%, respectively, compared with doxorubicin control), while at the concentration of 100 μM, 1 showed hepatoprotective activity against CCl4-induced hepatotoxicity on HepG2 cells (34.3%, compared with quercetin control).

3. 3

   Diabète mellitus de type II

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Rao BS (2014)

     Extrait In the present study, we investigated the neuroprotective effect of ethanolic extract of Cleome viscosa (EECV) against streptozotocin (STZ) induced diabetic neuropathy in Wistar rats. Diabetic neuropathy (DN) is a secondary microvascular complication of diabetes causing damage to the nerves and is characterized by fall in nerve conduction velocity, severe pain, impaired sensation and degeneration of nerve fibres.

   • Selon Yarrappagaari S (2020)

     Extrait The current research is to develop an easy & eco-friendly method for the synthesis of three different concentrations of silver nanoparticles (1mMCvAgNPs, 2mMCvAgNPs & 3mMCvAgNPs) using aqueous whole plant extract of Cleome viscosa & to evaluate their antibacterial, antioxidant & antidiabetic properties. Hence, to validate our results, the in vivo studies at the molecular level are needed to develop CV as an antibacterial, antioxidant & anti-diabetic agent.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.