Clerodendrum philippinum (Karaktè-dézonm) : vertus médicinales en extraction alcoolique

Clerodendrum philippinum (Karaktè-dézonm, caractère-des-Hommes, The Character of Man) — famille Verbénacées.

Synonymes scientifiques : Agricolaea fragrans (V.) Schrank, Clerodendrum chinense var. hamrense Das, S & B, C chinense var. parviflorum M.R.A, C chinense var. plenum M.R.Almeida, C chinense var. simplex (M) S.L.Chen, C fragrans Willd., C fragrans f. pleniflorum (Schauer) Standl. & Steyerm., C fragrans var. pleniflorum Schauer, C japonicum (Jacq.) G, C lasiocephalumC.BC, C macradenium-Miq, C philippinum f. subfertile Moldenke, C riedelii Oliv., C roseum Poit., Cryptanthus chinensis Osbeck, Ovieda fragrans (V.) H., Volkameria fragrans Vent., V japonica Jacq..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 11 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 52 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Infection bactérienne : Escherichia coli &. Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumonia, Bacillus subtilis, Corynebacterium kroppenstedtii & Vibrio cholerae

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pranati D (2018)

     Extrait Staphylococcus aureus, Pseudomonas aeruginosa, Streptococcus pneumonia, Bacillus subtilis, Corynebacterium kroppenstedtii & Vibrio cholerae by disc diffusion method. Clerodendrum philippinum plant was evaluated for its secondary metabolites & antibacterial activity.

   • Selon Venkatanarasimman B (2012)

     Extrait Roots & leaf extracts of Clerodendrum philippinum have been used for the treatment of rheumatism, asthma & other inflammatory diseases. aureus, Bacillus & Klebsiella & minimum inhibitory concentration of CP.

   • Selon Nababan JL (2021)

     Extrait The results of antibacterial test against the oral bacteria Streptococcus mutans ATCC (25175) showed that 0.5% & 0.75% of the oral antibacterial mouthwash was found to be effective as oral antibacterial with an average inhibition zone diameter of 16.55 & 16.9 mm. Clerodendrum fragrans is a local plant of North Sumatra, containing secondary metabolites of alkaloids, steroids, flavonoids, triterpenoids, saponins, tannins, & quinones that have bioactivity such as antibacterial & antioxidant.

   • Selon Simorangkir M (s.d.)

     Extrait Sarang banua plant, known as Clerodendrum fragrans is a division of the Verbenaceae family found in Simalungun district of Indonesia, which is traditionally used as medicinal plants. aureus (90.0%) with inhibitory zones of 11.25 ± 0.2 mm, meanwhile the n-hexane (non-polar) extract had the greatest inhibition against Gram-negative bacteria of the E.

   • Selon Lalitha KG (2017)

     Extrait The research work deals with the ethanolic extract of Clerodendrum philippinum flowers for anti-anxiety & central nervous system depressant activity. The CP flowers are known to contain sterols, flavonoid, glycosides & phenyl propanoid derivatives as chemical components & are reported to have antifungal activity.

2. 2

   -cancer : traitement adjuvant du carcinome mammaire, pulmonaire et utérin

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Chittasupho C (2023)

     Extrait This study aims to investigate the antioxidant & anti-cancer activities of Clerodendrum chinense leaf ethanolic extract. CC leaf extract exhibited anti-proliferative activity against A549 lung cancer cells in a dose- & time-dependent manner, with the IC50 value of 340.63 ± 89.43, 210.60 ± 81.74, and 107.08 ± 28.90 µg/mL after treatment for 24, 48, and 72 h, respectively.

   • Selon Barung EN (2021)

     Extrait RESULTS: The results showed that ethanol extract, hexane fraction, ethyl acetate fraction, & water-soluble fraction of CF had anticancer activity on A549 lung cancer cells. fragrans leaves obtained in Malalayang I Timur Village, Malalayang District, Manado City, North Sulawesi Province, while the subjects in this study were A549 lung cancer cells from Cell-Culture Laboratory, Faculty of Pharmacy, Universitas Padjadjaran Bandung.

   • Selon Gogoi B (2017)

     Extrait Clerodendrum indicum & Clerodendrum serratum are reported to have anticancer activity; therefore, a study was carried out to identify selective anticancer agents from these plants’ species. We predicted five compounds, namely apigenin 7-glucoside, hispidulin, scutellarein-7-O-beta-D-glucuronate, acteoside & verbascoside, to be potential binding therapeutics for cancer target proteins.

   • Selon Qi J (2021)

     Extrait As part of our continuing efforts toward the discovery of the biologically active diterpenoids from medicinal plants, six new C-ring aromatized abietane diterpenoids, clerodenoids A—F (1—6), were isolated from Clerodendrum chinense. Compounds 5 & 6 displayed strong antiproliferative activities against A549 & HL-60 cell lines.

   • Selon Kalonio DE (2017)

     Extrait Kalonio DE et al, Anticancer activity of plants of the genus Clerodendrum (Lamiaceae).

3. 3

   Cancer : traitement adjuvant du carcinome pulmonaire

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Barung EN (2021)

     Extrait RESULTS: The results showed that ethanol extract, hexane fraction, ethyl acetate fraction, & water-soluble fraction of CF had anticancer activity on A549 lung cancer cells. fragrans leaves obtained in Malalayang I Timur Village, Malalayang District, Manado City, North Sulawesi Province, while the subjects in this study were A549 lung cancer cells from Cell-Culture Laboratory, Faculty of Pharmacy, Universitas Padjadjaran Bandung.

   • Selon Chittasupho C (2023)

     Extrait This study aims to investigate the antioxidant & anti-cancer activities of Clerodendrum chinense leaf ethanolic extract. CC leaf extract exhibited anti-proliferative activity against A549 lung cancer cells in a dose- & time-dependent manner, with the IC50 value of 340.63 ± 89.43, 210.60 ± 81.74, and 107.08 ± 28.90 µg/mL after treatment for 24, 48, and 72 h, respectively.

   • Selon Qi J (2021)

     Extrait As part of our continuing efforts toward the discovery of the biologically active diterpenoids from medicinal plants, six new C-ring aromatized abietane diterpenoids, clerodenoids A—F (1—6), were isolated from Clerodendrum chinense. Compounds 5 & 6 displayed strong antiproliferative activities against A549 & HL-60 cell lines.

   • Selon Gogoi B (2017)

     Extrait Clerodendrum indicum & Clerodendrum serratum are reported to have anticancer activity; therefore, a study was carried out to identify selective anticancer agents from these plants’ species. We predicted five compounds, namely apigenin 7-glucoside, hispidulin, scutellarein-7-O-beta-D-glucuronate, acteoside & verbascoside, to be potential binding therapeutics for cancer target proteins.

   • Selon Kalonio DE (2017)

     Extrait Kalonio DE et al, Anticancer activity of plants of the genus Clerodendrum (Lamiaceae).

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.