Coccinia indica (Ti-konkonb-Lyenn) : vertus médicinales en extraction alcoolique

Coccinia indica (Ti-konkonb-Lyenn, Ti-Goud, Petite concombre-liane, Petite gourde, Small vine cucumber, Small gourd) — famille Cucurbitacées.

Synonymes scientifiques : Coccinia grandis-(L)-Voigt..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 17 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 69 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Parties aériennes. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shibib BA (2012)

     Extrait To explore how ethanolic extract of Coccinia indica affects normal & diabetic rats. CONCLUSION :Results suggested that CI extract had anti-hyperglycaemic & anti-ureogenic effects on the diabetic rats as judged by the decreased level of blood glucose & fatty acid & hepatic arginase activity,.

   • Selon Venkateswaran S (2003)

     Extrait The antioxidant effect of an ethanolic extract of Coccinia indica leaves, an indigenous plant used in Ayurvedic medicine in India, was studied in Streptozotocin-diabetic rats. The extract also causes a significant increase in reduced glutathione, superoxide dismutase, catalase, glutathione peroxidase & glutathione-S-transferase in liver & kidney of streptozotocin diabetic rats, which clearly shows the antioxidant property of CLEt.

   • Selon Venkateswaran S (2003)

     Extrait The present study was carried out to investigate the antioxidant effect of an ethanolic extract of Coccinia indica leaves, an indigenous plant used in Ayurvedic Medicine in India, in Streptozotocin-diabetic rats. The effect of CLEt at 200 mg/kg body weight was more effective than glibenclamide.

   • Selon Kumar Balaraman A (2010)

     Extrait Antihyperglycemic & hypolipidemic effects of ethanol extract of aerial parts of Melothria maderaspatana & Coccinia indica were evaluated in STZ induced diabetes in Sprague-Dawley rats. Administration of EEMm or EECi to STZ-diabetic rats caused significant antihyperglycemic & hypolipidemic effects (p < 0.001).

   • Selon Mohammed S Iqbal (2016)

     Extrait Results: Treatment of experimental rats with diabetes induced by streptozotocin by ethanolic leaf extract (500 mg/kg) caused significant (P < 0.001) reduction in blood glucose (312–169 mg/100 mL), increase in body weight (181–210 g) & serum insulin (1.28–3.10 IU/dL). to evaluate antidiabetic & antioxidative properties of Coccinia grandis leaf extract in experimental diabetic rats & to study the co-relation of the two in vivo.

2. 2

   Hépatopathie congestive, trouble hépato-cardiaque

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Vinoth-Kumar G (2019)

     Extrait Coccinia indica is indigenous plant wildly used in traditional medicinal system including Ayurvedic, Siddha & Unani. In this study, the protective effect of CI leaf extract against enalapril induced hepatotoxicity proves, the plant has many medicinal properties.

   • Selon Shibib BA (2012)

     Extrait To explore how ethanolic extract of Coccinia indica affects normal & diabetic rats. CONCLUSION :Results suggested that CI extract had anti-hyperglycaemic & anti-ureogenic effects on the diabetic rats as judged by the decreased level of blood glucose & fatty acid & hepatic arginase activity,.

   • Selon Kumar Balaraman A (2010)

     Extrait Antihyperglycemic & hypolipidemic effects of ethanol extract of aerial parts of Melothria maderaspatana & Coccinia indica were evaluated in STZ induced diabetes in Sprague-Dawley rats. After 14 days experimental period, rats were sacrificed by cervical decapitation, blood & liver samples were collected.

   • Selon Jamwal A (2019)

     Extrait Coccinia indica Wight. Quercetin caused slight change in hepatic marker enzymes and kidney functions markers in diabetic rats.

   • Selon Attanayake A (2016)

     Extrait Leaves of ivy gourd; Coccinia grandis (L.) Voigt (Family: Cucurbitaceae) is one of the well-known leafy vegetables, which has been consumed by Sri Lankans for centuries. In addition, the optimum effective therapeutic dose of the aqueous CG extract was found to be safe in terms of hepatotoxicity, renotoxicity, hematotoxicity in vivo.

3. 3

   Infection bactérienne : Enterobacter aerogenes, Pseudomonas aeruginosa, Staphylococcus epidermidis, Bacillus subtilis & Salmonella typhimurium

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Hussain A (2010)

     Extrait The aqueous & organic solvent (Petroleum ether, chloroform & ethanol) extracts from the leaves of CI(Cucurbitaceae) were tested against Enterobacter aerogenes, Pseudomonas aeruginosa, Staphylococcus epidermidis, Bacillus subtilis & Salmonella typhimurium by agar well diffusion method & broth dilution method. The aim of the present research was focused on investigating the antibacterial & preliminary phytochemical properties of Coccinia indica (W.A.) via in vitro approach.

   • Selon Sakharkar P (2017)

     Extrait The antibacterial activities of the extracts were tested against Staphylococcus aureus, Enterococcus faecalis, Escherichia coli & Pseudomonas aeruginosa using the modified Kirby-Bauer diffusion method & compared against erythromycin. Little knowledge is available on the antimicrobial and antioxidant properties of Coccinia grandis fruits & no study has reported on its cell proliferative property.

   • Selon Al-Madhagy SA (s.d.)

     Extrait CG50 hydrogel showed a pronounced inhibition of the bacterial growth in wounds infected by Bacillus cereus in rats comparable to those treated with hydrogel base only showing 85.08 & 16.50% inhibition for the bacterial growth for the CG50 hydrogel & hydrogel base, respectively. A polyphenolic-rich fraction (CG50) was obtained from the methanol extract of Coccinia grandis leaves by chromatographic fractionation over a Diaion column using 50% aqueous methanol.

   • Selon Chinni SV (2021)

     Extrait the present study was planned to characterize & analyze the antimicrobial activity of silver nanoparticles (AgNP) biosynthesized using a Coccinia indica leaf (CIL) ethanolic extract. The biogenic AgNP & CIL extracts were further investigated against different bacterial strains for their antimicrobial activity.

   • Selon Rahman FL (s.d.)

     Extrait In this present study, the leaf extracts of Coccinia grandis L., were subjected to evaluation of the phytochemical screenings, thrombolytic, membrane stabilizing, antioxidant, antimicrobial & cytotoxic activity. Leave extracts of CG revealed moderate antimicrobial activity against some gram positive and gram negative microorganisms.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.