Coix lacryma (Grenn Jôb) : vertus médicinales en extraction alcoolique

Coix lacryma (Grenn Jôb, Graines de Job, Job’s Seeds) — famille Poacées.

Synonymes scientifiques : Coix lacryma-jobi var. mayuen, orth. Var, C var. ma-yuen (Rom.Caill.) Stapf.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 24 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 116 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome hépatique, gastrique,& utérin

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Devaraj RD (2020)

     Extrait Coix seed constituents have strong antioxidant, anti-inflammatory, anti-obesity activity, stimulate reproductive hormones, promote uterine contraction & modulate gut microbiota. Coix has strong chemical constituents to inhibit enzymes of cyclooxygenase (COX), fatty acid synthase, matrix metalloproteinases & liver cholesterol synthesis.

   • Selon He W (2020)

     Extrait Adlay (Coix lacryma-jobi L.) bran has recently attracted much attention because it is rich in neutral oil, which promises its potential usage as a health-promotion product. The results proved that crude ABO extracted by the ethanol-water method probably had a potential higher anticancer function than Kanglaite® injection.

   • Selon LI H (2024)

     Extrait Numerous pharmacological effects of Coix seed have been demonstrated through modern pharmacological studies, such as hypoglycemia, improving liver function, anti-tumor, regulating intestinal microbiota, improving spleen function, & anti-inflammatory effects. In addition to its anti-tumor effect, it also has pharmacological effects such as hypoglycemia, improving liver function, regulating intestinal microbiota, improving spleen function, & anti-inflammatory effects.

   • Selon Gu L (2021)

     Extrait Coix lacryma-job seed oil (CLSO) is an active component extracted from Coix lacryma-jobi seed (CLS) which has been found to be effective of reducing blood fat & antioxidative. Our result showed that CLSO decreased the liver/body weight ratio, lowered the total cholesterol (TC) & triacylglycerol (TG), & elevated the high-density lipoprotein (HDL) in serum.

   • Selon HUANG CC (2021)

     Extrait Coix lacryma-jobi var. The results indicates that AB-SCF displays a prevention of dramatic body weight gains, lower levels of serum TG, TC, LDL-C & higher in HDL-C, amelioration of cardiovascular risk, alleviation of hepatic TG, TC & lipid peroxidation, & enhancement on cholesterol metabolism with higher bile acid excretion.

2. 2

   Hépatopathie grasse non alcoolique, (Non-Alcoholic Fatty Liver Disease (NAFLD)

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Gu L (2021)

     Extrait The lipid metabolism disorder is the key role of Nonalcoholic fatty liver disease (NAFLD). Coix lacryma-job seed oil (CLSO) is an active component extracted from Coix lacryma-jobi seed (CLS) which has been found to be effective of reducing blood fat & antioxidative.

   • Selon He W (2020)

     Extrait Adlay (Coix lacryma-jobi L.) bran has recently attracted much attention because it is rich in neutral oil, which promises its potential usage as a health-promotion product.

   • Selon Devaraj RD (2020)

     Extrait Coix has strong chemical constituents to inhibit enzymes of cyclooxygenase (COX), fatty acid synthase, matrix metalloproteinases & liver cholesterol synthesis. The annual millet Coix lacryma-Jobi L.

   • Selon LI H (2024)

     Extrait Numerous pharmacological effects of Coix seed have been demonstrated through modern pharmacological studies, such as hypoglycemia, improving liver function, anti-tumor, regulating intestinal microbiota, improving spleen function, & anti-inflammatory effects. Coix lacryma-jobi var.

   • Selon HUANG CC (2021)

     Extrait Coix lacryma-jobi var. The results indicates that AB-SCF displays a prevention of dramatic body weight gains, lower levels of serum TG, TC, LDL-C & higher in HDL-C, amelioration of cardiovascular risk, alleviation of hepatic TG, TC & lipid peroxidation, & enhancement on cholesterol metabolism with higher bile acid excretion.

3. 3

   HTA, rétention hydrique, oedème

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ouyang Y (2022)

     Extrait The data generated from this study revealed the characteristic diversity of Coix collected from different locations, which will facilitate the utilization of antihypertensive peptides from glutelin –. Coix lacryma-jobi L.

   • Selon Zhang CF (2019)

     Extrait Results: The values of paw oedema, PGE2 & MMP-3 decreased from 1.46 ± 0.04 to 0.66 ± 0.07 cm3, from 126.2 ± 11.48 to 79.71 ± 6.8 pg/mL & from 142.7 ± 8.36 to 86.51 ± 5.95 ng/mL, respectively; the values of body weight increased from 177.25 ± 5.94 to 205 ± 6.52 g in HASE group. In addition, treatment of ASE reduced the levels of pro-inflammatory cytokines (IL-1β, TNF-α, IL-6, MCP-1), & increased the activities of antioxidant enzyme (GSH-Px, SOD, & CAT).

   • Selon Huang DW (2009)

     Extrait Subfractions AHE-Ea-J, AHE-Ea-K, & AHE-Ea-M had anti-inflammatory activities, as they counteracted the increased cellular production of nitric oxide & prostaglandin E2 induced by lipopolysaccharide by down-regulating inducible nitric oxide synthase & cyclooxygenase 2 expression. Eriodictyol (1), the ceramide (2S,3S,4R)-2-[(2'R)-2'-hydroxytetracosanoyl-amino]-1,3,4-octadecanetriol (2), & p-coumaric acid (3) were found in the subfractions, & the first two compounds appeared to be primarily responsible for the anti-inflammatory activity.

   • Selon Li SC (2011)

     Extrait Previous studies have shown that adlay has anti-tumour & anti-inflammatory activity.

   • Selon Devaraj RD (2020)

     Extrait Coix seed constituents have strong antioxidant, anti-inflammatory, anti-obesity activity, stimulate reproductive hormones, promote uterine contraction & modulate gut microbiota. The annual millet Coix lacryma-Jobi L.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.