Coriandrum sativum (Coriandre) : vertus médicinales en extraction alcoolique

Coriandrum sativum (Coriandre, Coriander) — famille Apiacées.

Synonymes scientifiques : Apium leptophyllum auct non (Pers.) Muell ex Benth, Coriandrum diversifolium Gilib., C. globosum Salisb, C. majus Gouan, C. melphitense Ten. & Guss., Selinum Coriandrum E.H.L. Krause.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 25 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 142 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Normalisation des paramètres sériques : SGOT, SGPT, ALP, Bilirubine

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sharma B (2016)

     Extrait Results: After 28 days treatment the extracts significantly (p<0.001) reduce serum glucose level and recovered liver function tests (p<0.001) (SGOT, SGPT, ALP & Bilirubin) as well glycosylated haemoglobin (p<0.001). The aim of the present study was to evaluate the antidiabetic & hepatoprotectivity of ethanolic extracts of Coriandrum sativum in alloxan induced diabetic rat & find out the harmonious activity of the extract.

   • Selon Pandey A (2011)

     Extrait Materials & methods: This study was aimed at investigating the hepatoprotective activity of CS against carbon tetrachloride (CCl4), with estimation of serum glutamyl oxaloacetic acid transaminase (SGOT), serum glutamyl pyruvate transaminase (SGPT), alkaline phosphatase (ALP) & bilirubin, & with liver histopathology. CS signifies hepatoprotection by reducing the liver weight, activities of SGOT, SGPT, & ALP, & direct bilirubin of CCl (4) intoxicated animals.

   • Selon Talaei R (s.d.)

     Extrait Treatment with CS extract significantly decreased bio- chemical parameters, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), lactate dehydrogenase (LDH) & creatine phosphokinase (CPK), & improved tissue damage & decreased iron accumulation in the liver compared to the iron overload group (P < 0.05). Conclusions: The study showed that the hydro-alcoholic extract of C.S has iron-chelating & liver protective effects similar to deferoxamine against experimental iron overload condition in rats,.

   • Selon Kansal Leena (2011)

     Extrait Treatment with coriander significantly reduced the adverse effects related to most of biochemical parameters altered in animals treated with lead, related to hepatic & renal oxidative stress. The effect of these treatments in influencing the lead induced changes on hepatic and renal oxidative stress and biochemical changes along with histopathological alterations in soft tissues was studied.

   • Selon Mostafa Saeed (2014)

     Extrait The possible protective effect of Coriandrum sativum seeds methanolic extract on hepatorenal toxicity induced by sodium arsenite in albino rats.

2. 2

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Metformine-like, Acarbose-like, Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sharma B (2016)

     Extrait The aim of the present study was to evaluate the antidiabetic & hepatoprotectivity of ethanolic extracts of Coriandrum sativum in alloxan induced diabetic rat & find out the harmonious activity of the extract. Methods: The alloxan (150 mg/kg, i.p) used for induction of diabetes after making diabetic model the ethanolic extract of C sativum leaves used at a dose of 200 a&400 mg/kg b.w.

   • Selon Aligita W (2018)

     Extrait Diabetes mellitus is one of the metabolic disorders marked by hyperglycemia caused by carbohydrate, fat, & protein metabolism abnormality. There is a significant increase in diabetes case every year in Indonesia & the long-term use of antidiabetic drugs can cause various side effects.

   • Selon Sharma B (2017)

     Extrait To evaluate the antidiabetic & rejuvenating capability of tissues on alloxan induced diabetic rats under the effect of ethanolic leaf extract of Coriandrum sativum. The effect of ethanolic leaf extract of CS leaf extract on serum blood glucose, insulin, lipase, α- amylase & LDH as well as kidney function test [urea, uric acid, albumin, protein & creatinine] were measured in the alloxan induced diabetic rats.

   • Selon Eldi M (s.d.)

     Extrait In the present study, an ethanol extract of the seeds was investigated for effects on insulin release from the pancreatic beta cells in streptozotocin-induced diabetic rats. Administration of streptozotocin decreased the number of beta cells with insulin secretory activity in comparison with intact rats, but treatment with the CS seed extract (200 mg/kg) increased significantly the activity of the beta cells in comparison with the diabetic control rats.

   • Selon Aissaoui A (2011)

     Extrait Results: A single dose of CS-extract or GLB suppressed hyperglycemia in OHH rats, & normo-glycemia was achieved at 6-h post-dose; there was no effect on lipids, TG or insulin, but IR decreased significantly. The use of an aqueous extract of Coriandrum sativum seeds (CS-extract) in Moroccan traditional treatment of diabetes remains to be experimentally validated.

3. 3

   Infection bacterienne : S. aureus, Bacillus humilis, Klebsiella pneumonia, E. coli, Ps. Aeruginosa, S. typhi

   Partie usitée : Semence.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Matasyoh JC (2009)

     Extrait The oil was screened for antimicrobial activity against both Gram positive (Staphylococcus aureus, Bacillus spp.) & Gram negative (Escherichia coli, Salmonella typhi, Klebsiella pneumonia, Proteus mirabilis, Pseudomonas aeruginosa) bacteria & a pathogenic fungus, Candida albicans. The oil showed pronounced antibacterial & antifungal activity against all of the microbes tested, except for P.

   • Selon Bakhiet O (2006)

     Extrait Petroleum ether, ethanolic and water extracts of Petroselinum sativum and Coriandrum sativum were screened for antibacterial activity against one standard gram-positive bacterium (Staphylococcus aureus) & three gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa & Salmonella typhi). sativum was active against only Pseudomonas aeruginosa.

   • Selon Charan AA (2013)

     Extrait coli, Bacillus pumila, & Klebsiella pneumonia to determine the sample’s antibacterial activity. The present study was carried out to evaluate the antibacterial and antioxidant activity of the crude ethanolic an acetone extracts of Mentha Piperata, Spinacia oleracea & Coriandrum sativum.

   • Selon Cao XZ (2012)

     Extrait Antibacterial experiment indicated that only water extract presented significant antimicrobial activity & the minimum inhibition concentration (MIC) was below 10% of original extract. The results showed that antibacterial activity of coriander extracts was stable under heating & had the best antibacterial effects at pH 6 with 2.0% NaCl concentration,.

   • Selon Begnami (2010)

     Extrait The aim of this study was to evaluate the chemical and antifungal activity of the essential oil from Coriandrum sativum L. In conclusion, the EO and its fractions could be used as potential antimicrobial agents to treat or prevent Candida yeast infections.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.