Costus speciosus (Kann Kongo) : vertus médicinales en extraction alcoolique

Costus speciosus (Kann Kongo, Kann dlo, Ti dégonflé, Canne-à-Congo, canne-d ’eau, It’s gone flat, water pipe) — famille Costacées.

Synonymes scientifiques : Banksia speciosa-K, Costus spicatus-(Jacq)-Sw.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 51 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome mammaire et hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon NAIR SVG (2014)

     Extrait This is the first report to demonstrate in vitro anticancer activity of leaf extract of CS in relation to liver cancer,. speciosus on the growth of human hepatocellular carcinoma (HepG2) cell & understand possible mechanisms of its action.

   • Selon Verma N (2009)

     Extrait The hepatoprotective activity of the ethanolic extract of the rhizomes of Costus speciosus (Koenig) Sm. The extract registered a significant fall in the levels of serum glutamyl oxalacetic acid transaminase (SGOT), serum glutamyl pyruvate transaminase (SGPT), alkaline phosphatase (ALKP), serum bilirubin (SBLN) & liver inflammation supported by histopathological studies on liver, thus exhibited a significant hepatoprotective activity.

   • Selon Viduranga Y (2015)

     Extrait Costus speciosus & Coccinia grandis are plants which contain reservoirs of anti-diabetic effects as well as other medicinal properties. These plants have been known to demonstrate pharmacological activities such as anti-inflammatory, anti-microbial, antioxidant, anti-dyslipidemic & anti-cancer.

   • Selon Selim S (2015)

     Extrait Results: The results indicated that the treatment of HepG2 cells with the sample resulted in a cytotoxic effect as concluded from the IC50 value 32.62 μg/ml, while the treatment of HepG2 cells with paclitaxel, a known anti-cancer drug, resulted in an IC50 value of 0.48 μg/ml. Conclusions: The results presented here may suggest that diosgenin isolated from CS possess anticancer & apoptotic effects on cell proliferation, & therefore, can be used as pharmaceuticals drug,.

   • Selon Shediwah FM (2019)

     Extrait An extract of Costus speciosus (CSE), an herb widely used in folk medicine, was evaluated for its antioxidant, antihyperlipidemic & ameliorating effects on histopathological changes in atherogenic rabbits. Total protein increased in the liver, heart & aorta after treatment with CSE & also a marked improvement in histopathological parameters was demonstrated.

2. 2

   Troubles hépatiques : anormalité des paramètres sériques : SGOT, SGPT, ALKP(Alcaline Phosphatase), Bilirubine, protéine totale

   Partie usitée : Rhizome.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Verma N (2009)

     Extrait The extract registered a significant fall in the levels of serum glutamyl oxalacetic acid transaminase (SGOT), serum glutamyl pyruvate transaminase (SGPT), alkaline phosphatase (ALKP), serum bilirubin (SBLN) & liver inflammation supported by histopathological studies on liver, thus exhibited a significant hepatoprotective activity. The hepatoprotective activity of the ethanolic extract of the rhizomes of Costus speciosus (Koenig) Sm.

   • Selon NAIR SVG (2014)

     Extrait Costus speciosus is a medicinal plant commonly known as wild ginger distributed in South and Southeast Asian countries. speciosus on the growth of human hepatocellular carcinoma (HepG2) cell & understand possible mechanisms of its action.

   • Selon Reavathy J (2014)

     Extrait The antidiabetic effect of ethanolic extract of Costus speciosus rhizome was determined. The ethanolic extract shows significant reduction in blood glucose, glycosylated haemoglobin, blood urea, serum uric acid, serum creatinine, triglycerides, total cholesterol, phospholipids, low density lipoprotein (LDL), very low-density lipoprotein (VLDL), & increase in liver glycogen, insulin & lactate dehydrogenase (LDH).

   • Selon Shediwah FM (2019)

     Extrait Total protein increased in the liver, heart & aorta after treatment with CSE & also a marked improvement in histopathological parameters was demonstrated. An extract of Costus speciosus (CSE), an herb widely used in folk medicine, was evaluated for its antioxidant, antihyperlipidemic & ameliorating effects on histopathological changes in atherogenic rabbits.

   • Selon Bavarva JH (2008)

     Extrait In the present study, the antihyperglycemic, antihyperlipemic & antioxidant potency of an ethanol extract of Costus speciosus root was investigated in alloxan-induced diabetic male (Charles Foster) rats. These doses also reversed the hyperlipidemia by reducing plasma total lipid (12.87%, 178.24%), cholesterol (21.92%, 30.77%) & triglyceride (25.32%, 33.99%) & improved hepatic antioxidant enzyme activities.

3. 3

   Diabète mellitus de type II

   Partie usitée : Rhizome. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Daisy P (2008)

     Extrait rhizome extracts on biochemical parameters in streptozotocin (STZ)-induced male diabetic Wistar rats. Thus, this study shows that the CS hexane extract has antihyperglycemic & hypolipidemic activity, is able to ameliorate the diabetic state & is probably a source of hypoglycemic compounds.

   • Selon Reavathy J (2014)

     Extrait The antidiabetic effect of ethanolic extract of Costus speciosus rhizome was determined. Our experimental findings with respect to the mechanism of action of extract in alloxan induced diabetic rats suggest that it enhances insulin secretion by the islets of Langerhans, enhances peripheral glucose utilization & increases serum protein levels.

   • Selon Revathy J (2011)

     Extrait Revathy J et al, An experimental evaluation of the antidiabetic & antioxidant effect of Costus speciosus rhizome extract in alloxan-induced albino rat, BioSci Biotechnol Res Asia, 2011-.

   • Selon Eliza J (2011)

     Extrait Normalizing effects of Costus speciosus rhizome crude extracts & its fractions on diabetic complications in STZ-induced diabetic rats.

   • Selon Ferosakhan M (s.d.)

     Extrait It is concluded from the present study that the Costus species extracts potentiate the antidiabetic activity & can be used as an alternate for the treatment of diabetes after completing successful clinical trials. Fresh elder leaves of species viz., Costus pictus & Costus speciosus were collected from Western Ghats, Tamil Nadu.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.