Costus spicatus (Kann Kongo) : vertus médicinales en extraction alcoolique

Costus spicatus (Kann Kongo, Kann dlo, Ti dégonflé, Canne-à-Congo, canne-d ’eau, Petit dégonflé, water cane, Little deflator) — famille Costacées.

Synonymes scientifiques : Alpinia spicata-Jacq, Amomum petiolatum-Lam, Costus cylindrica-Aubl non L, C micranthus -Gag..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 20 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabete mellitus de type II

   Partie usitée : Rhizome. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sivalungam MA (2019)

     Extrait Anti-diabetic effect of plant Costus spicatus. ECS & Glibenclamide of STZ induced diabetic animals restored the normal plasma glucose levels & SGOT, SGPT & ALP levels without damaging the pancreas.

   • Selon Femi-Olabisi F (2021)

     Extrait In this study, the inhibitory activities of phytosterols & saccharides from aqueous extract of Costus spicatus rhizome were investigated against phosphoenol-pyruvate carboxykinase (PEPCK), α-amylase, β-glucosidase, & fructose 1,6-biphosphatase (FBPase) in silico as potential novel therapeutic targets for T2DM-associated-PCOS. Insulin resistance is the hall mark of PCOS as it predisposes the affected subjects to a higher risk of impaired glucose tolerance & type 2 diabetes mellitus (T2DM).

   • Selon Sivalungam AM (2021)

     Extrait The characteristic phytochemical constituents are steroids, tri-terpenoid, Anthraquinone glycosides, proteins are established in the concentrates of Costus spicatus flower. Oral administration of effect of ECS to diabetic induced rats at dosage of 500 mg/kg body weight resulted during significant decrease of elevated blood glucose & hepatic transaminase enzyme levels, at different treatment period (0 th day, 28 th day & 45 th day) which also showed the structural changes in cytoarchitecture of STZ induced diabetic rats.

   • Selon Sivalungam MA (2023)

     Extrait The study found that Costus spicatus extract had a beneficial effect on body weight & blood glucose levels in diabetic rats. The study found that the CS leaf extract was effective in improving the antioxidant activity of important parameters such as SOD, CAT, GPx, & GR, & protected against hyperglycemia and oxidative damage in type 2 diabetes-induced hepatorenal functions both in vitro & in vivo .

   • Selon Keller AC (2009)

     Extrait More investigation is needed to more fully explore dosages & the possible utility and biological activity of this common Dominican herbal remedy for the treatment of type 2 diabetes mellitus. Insulina was identified as Costus spicatus.

2. 2

   Diabète mellitus de type II

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Sivalungam AM (2021)

     Extrait The characteristic phytochemical constituents are steroids, tri-terpenoid, Anthraquinone glycosides, proteins are established in the concentrates of Costus spicatus flower. Oral administration of effect of ECS to diabetic induced rats at dosage of 500 mg/kg body weight resulted during significant decrease of elevated blood glucose & hepatic transaminase enzyme levels, at different treatment period (0 th day, 28 th day & 45 th day) which also showed the structural changes in cytoarchitecture of STZ induced diabetic rats.

   • Selon Sivalungam MA (2019)

     Extrait Anti-diabetic effect of plant Costus spicatus. ECS & Glibenclamide of STZ induced diabetic animals restored the normal plasma glucose levels & SGOT, SGPT & ALP levels without damaging the pancreas.

   • Selon Femi-Olabisi F (2021)

     Extrait Insulin resistance is the hall mark of PCOS as it predisposes the affected subjects to a higher risk of impaired glucose tolerance & type 2 diabetes mellitus (T2DM). In this study, the inhibitory activities of phytosterols & saccharides from aqueous extract of Costus spicatus rhizome were investigated against phosphoenol-pyruvate carboxykinase (PEPCK), α-amylase, β-glucosidase, & fructose 1,6-biphosphatase (FBPase) in silico as potential novel therapeutic targets for T2DM-associated-PCOS.

   • Selon Sivalungam MA (2023)

     Extrait The study found that Costus spicatus extract had a beneficial effect on body weight & blood glucose levels in diabetic rats. The study found that the CS leaf extract was effective in improving the antioxidant activity of important parameters such as SOD, CAT, GPx, & GR, & protected against hyperglycemia and oxidative damage in type 2 diabetes-induced hepatorenal functions both in vitro & in vivo .

   • Selon Keller AC (2009)

     Extrait More investigation is needed to more fully explore dosages & the possible utility and biological activity of this common Dominican herbal remedy for the treatment of type 2 diabetes mellitus. Insulina was identified as Costus spicatus.

3. 3

   Dermatophytose: Epidermophyton floccosum, Trichophyton mentagrophytes, T. rubrum, Microsporum gypseum & M. canis

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Silva DN (2008)

     Extrait rubrum, Microsporum gypseum & Epidermophyton floccosum, the higher activity being against M. These results suggest, for the first time, the antifungal effectiveness of CS leaves, namely of a flavonoid-rich fraction, for dermatophytosis which are referred to as „tinea “infections.

   • Selon Ali A (2022)

     Extrait Costus spicatus (spiked spiral flag ginger) is traditionally utilised for its advantages such as antidiabetic, antihyperlipidemic, diuretic, antimicrobial, & anticancer properties. Thus, this study tested the nephroprotective effect of the polyphenol-rich extract of Costus spicatus leaves (PCSL) using preclinical models, including the HeK cell line & Wistar albino rats against cisplatin-induced toxicity.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.