Cucumis melo (Milon) : vertus médicinales en extraction alcoolique

Cucumis melo (Milon, Melon) — famille Cucurbitacées.

Synonymes scientifiques : Bryonia callosa Rottler, Cucumis melo var. microcarpus Pangalo C microcarpus (Pangalo) Pangalo, C moschatus Gray, C odoratissimus Moench, C pubescens Willd., 1805, C callosus (Rottler) Cogn. ex Engl., C chate L., Cucumis chito E.Mor., C cognata Fenzl ex Hook.f., C conomon Thunb., C deliciosus Salisb., Cs flexuosus L., C melo var. cultus Kurz, Melo sativus Vassilcz..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 23 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 103 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome hépatique

   Partie usitée : Fruit. Profil pharmacologique documenté : Cyclophosphamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Vidya R (2021)

     Extrait In this present research work, the anticancer efficacy of Cucumis melo fruit extract & its silver nanoparticles was explored. The levels of serum tumor markers viz., Alpha feto protein (AFP) & Carcinoembryonic antigen (CEA) elevated in rats induced with DEN, which then were reduced following CM fruit treatment, indicating the anticancer activity of the drug.

   • Selon Bouazzaoui N (2016)

     Extrait Bouazzaoui N et al, Fatty acids & minerals composition of Melon (cucumis melo L.

   • Selon Rolim PM (2018)

     Extrait To assess the antiproliferative potential in human cancer cell lines, such as kidney carcinoma, colorectal carcinoma, cervical adenocarcinoma & cervical carcinoma, MTT assay was performed. Melon (Cucumis melo L.) has high economic value and in recent years, its production has increased; however, part of the fruit is wasted.

   • Selon Rolim PM (2018)

     Extrait To assess the antiproliferative potential in human cancer cell lines, such as kidney carcinoma, colorectal carcinoma, cervical adenocarcinoma & cervical carcinoma, MTT assay was performed. Melon (Cucumis melo L.) has high economic value & in recent years, its production has increased; however, part of the fruit is wasted.

   • Selon Sibi P Ittiyavirah (2013)

     Extrait Sibi P Ittiyavirah et al, Studies of Cytotoxic Potential of Cucumis melo. Linn Fruit Aqueous Extract in Prostate Cancer Cell lines PC-3 Using MTT and Neutral Red Assay, Iranian J of Pharmacol & Ther, 2013.

2. 2

   Obésité, syndrome métabolique : insulino-résistance

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Lee D (2018)

     Extrait Cucumis is thus a promising treatment for obesity-induced insulin resistance & the inflammatory state. We found that Cucumis improved IR in obese mice & relieved inflammation in adipose tissu&blood.

   • Selon Parmar HS (2008)

     Extrait the peel extracts of Mangifera indica (MI), Cucumis melo (CM) & Citrullus vulgaris (CV) fruits in ameliorating the diet-induced alterations in dyslipidemia, thyroid dysfunction and diabetes mellitus have been investigated in rats. In the second experiment rats were maintained on pre-standardized atherogenic diet CCT (supplemented with 4% cholesterol, 1% cholic acid & 0.5% 2-thiouracil) to induce dyslipidemia, hypothyroidism & diabetes mellitus and the effects of the test peel extracts (200 mg/kg of MI & 100 mg/kg for CM & CV for 10 consecutive days) were studied by examining the changes in tissue LPO (in heart, liver & kidney), concentrations of serum lipids, thyroid hormones, insulin & glucose.

   • Selon Srivastav A (2020)

     Extrait C melo toluene fraction (CMTF) exhibited a significant (*P < 0.05) reduction of blood glucose level on the 28th day, i.e., 122 mg/dL, in comparison with the positive control group (streptozotocin (STZ)). Cucumis melo possesses several biological properties including antioxidant, anti-inflammatory, antibacterial, antihypothyroidism, & antiangiogenic activities.

   • Selon Gopalasatheeskumar K (2020)

     Extrait Antihyperglycemic & antihyperlipidemic activities of wild musk melon (Cucumis melo var. agrestis) in streptozotocin-nicotinamide induced diabetic rats.

   • Selon Babulreddy N (2013)

     Extrait Babulreddy N et al, Anti-Hyperglycemic Activity of Cucumis melo Leaf Extracts in Streptozotocin Induced Hyperglycemia in Rats, Inter J Pharm RAS, 2: 4 (2013): 22-7.

3. 3

   Diabete mellitus de type II

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Srivastav A (2020)

     Extrait C melo toluene fraction (CMTF) exhibited a significant (*P < 0.05) reduction of blood glucose level on the 28th day, i.e., 122 mg/dL, in comparison with the positive control group (streptozotocin (STZ)). Cucumis melo possesses several biological properties including antioxidant, anti-inflammatory, antibacterial, antihypothyroidism, & antiangiogenic activities.

   • Selon Parmar HS (2008)

     Extrait Rats, treated simultaneously with either of the peel extracts reversed the CCT-diet induced increase in the levels of tissue LPO, serum lipids, glucose, creatinine kinase-MB & decrease in the levels of thyroid hormones & insulin indicating their potential to ameliorate the diet induced alterations in serum lipids, thyroid dysfunctions & hyperglycemia/diabetes mellitus. the peel extracts of Mangifera indica (MI), Cucumis melo (CM) & Citrullus vulgaris (CV) fruits in ameliorating the diet-induced alterations in dyslipidemia, thyroid dysfunction and diabetes mellitus have been investigated in rats.

   • Selon Lee D (2018)

     Extrait Cucumis is thus a promising treatment for obesity-induced insulin resistance & the inflammatory state. This experimental study was designed to investigate the effects of Cucumis melo L.

   • Selon Gopalasatheeskumar K (2020)

     Extrait Antihyperglycemic & antihyperlipidemic activities of wild musk melon (Cucumis melo var. agrestis) in streptozotocin-nicotinamide induced diabetic rats.

   • Selon Babulreddy N (2013)

     Extrait Babulreddy N et al, Anti-Hyperglycemic Activity of Cucumis melo Leaf Extracts in Streptozotocin Induced Hyperglycemia in Rats, Inter J Pharm RAS, 2: 4 (2013): 22-7.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.