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Curcuma zedoria (Zédwè) : vertus médicinales en extraction alcoolique

Curcuma zedoria (Zédwè, Jenjanb-blan, Zédoaire, Gingembre blanc, Fleur de mai, White Jenjanb, White ginger, May flower) — famille Zingiberacées.

Synonymes scientifiques : Amomum zedoaria-Christm., Curcuma pallida-Lour, C xanthorryza-Recb..

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 22 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 116 références scientifiques pour cette espèce (détail intégral dans l’application).

Indications thérapeutiques en extraction alcoolique :

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

  1. Cancer :traitement adjuvant du carcinome ovarien, pulmonaire, œsophagien et hépatique

    Partie usitée : Rhizome.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon Zhong M (2025)

      Extrait Curcumae Rhizoma, a traditional Chinese medicine derived from the dried rhizome of Curcuma species, has long been used to treat liver-related disorders. In the classical medical text Taiping Shenghui Fang, it was recorded for the treatment of hepatocellular carcinoma (HCC) characterized by Qi stagnation & blood stasis.

    • Selon Ekowati Heny (2013)

      Extrait Measurements of parameters based on liver histopathology and the parameters of serum alanine amino transferase (ALT) & aspartate amino transferase (AST). Curcuma Xanthorrhiza, Curcuma longa & Zingiber officinale are commonly used as herbals in Indonesia and around the world.

    • Selon Soni KB (1992)

      Extrait Soni KB et al, Reversal of aflatoxin induced liver damage by turmeric & curcumin.

    • Selon DEVARAJ S (2010)

      Extrait The results of the present study indicated that CX possess hepatoprotective effects which could act as an effective treatment for acute hepatic diseases. The hepatoprotective activity of this extract was studied using ethanol- induced liver toxicity in rats.

    • Selon Yasni S (s.d.)

      Extrait Addition of essential oils (0.02%), prepared by steam distillation, to a purified diet resulted in a lower hepatic triglyceride concentration without influencing the serum triglyceride, whereas addition of the hexane-soluble fraction (0.5%) resulted in a lower concentration of serum as well as liver triglycerides. Rats fed the EO & hexane-soluble fraction had lower hepatic fatty acid synthase activity.

  2. Diabete mellitus de type II

    Partie usitée : Rhizome. Profil pharmacologique documenté : Glibenclamide-like.

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon ALIPIN K (2019)

      Extrait Diabetes mellitus (DM) is a metabolic disorder characterized by high blood glucose levels or hyperglycemia due to deficiency or ineffectiveness of insulin. This study aims to determine the effectiveness & optimum dosage combination CX rhizomes & AB fruit extract as anti-diabetic herbs in decreasing blood glucose levels, improve pancreas histopathology & the liver structure repair of diabetic male Wistar rats induced by streptozotocin.

    • Selon Rahmatullah M (2012)

      Extrait The objective of the present research was to evaluate in oral glucose tolerance tests, the anti-hyperglycemic potential of methanol extract of Curcuma zedoaria rhizomes & fruits of Sonneratia caseolaris, both of which are used as anti-diabetics in the folk medicinal system of Bangladesh. The demonstrated anti-hyperglycemic activities by rhizomes of CZ & fruits of S validate their folk medicinal uses & warrants further studies towards elucidation of responsible phytochemical components, which can be potentially more efficacious drugs for treatment of diabetes.

    • Selon Prasetyawan S (2023)

      Extrait Type 2 diabetes mellitus (T2DM) is a metabolic disease with a high risk of complications & mortality.

    • Selon Handjani J (2015)

      Extrait Streptozotocin (STZ) (Naclai tesque, Kyoto Japan) with a dose of 40 mg/kg was used to create hyperglycemia condition in those rats. The control group was consisted often rats, divided into two subgroups, as the positive control group (induced with 10 mg/kg of Glibenclamide) & the negative control group (induced with propylene glycol).

    • Selon Rahmat E (2021)

      Extrait To date, over 40 active compounds, including terpenoids, curcuminoids, & other phenolic compounds, have been isolated & identified from C.X Some pharmacological tests reported that CX has antioxidant, antimicrobial, anti-inflammatory, anticancer & antitumor, antidiabetic, & skincare & hepatoprotective properties. Curcuma xanthorrhiza Roxb., locally famed as Temulawak, has been extensively utilized in Indonesia as medicinal & nutritional plants since immemorial time.

  3. Prevention des troubles hépatiques causés par la Doxorubicine

    Partie usitée : Rhizome. Association synergique mentionnée : Curcuma longa, association synergique avec ZINGIBER OFFICINALE-Roscoe (Rhizome).

    Références scientifiques (courts extraits)

    Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

    • Selon Ekowati Heny (2013)

      Extrait Curcuma Xanthorrhiza, Curcuma longa & Zingiber officinale are commonly used as herbals in Indonesia and around the world. officinale has a protective effect in rats against liver damage induced by doxorubicin.

    • Selon Zhong M (2025)

      Extrait Curcumae Rhizoma, a traditional Chinese medicine derived from the dried rhizome of Curcuma species, has long been used to treat liver-related disorders. In the classical medical text Taiping Shenghui Fang, it was recorded for the treatment of hepatocellular carcinoma (HCC) characterized by Qi stagnation & blood stasis.

    • Selon DEVARAJ S (2010)

      Extrait The results of the present study indicated that CX possess hepatoprotective effects which could act as an effective treatment for acute hepatic diseases. The hepatoprotective activity of this extract was studied using ethanol- induced liver toxicity in rats.

    • Selon Yasni S (s.d.)

      Extrait Addition of essential oils (0.02%), prepared by steam distillation, to a purified diet resulted in a lower hepatic triglyceride concentration without influencing the serum triglyceride, whereas addition of the hexane-soluble fraction (0.5%) resulted in a lower concentration of serum as well as liver triglycerides. Rats fed the EO & hexane-soluble fraction had lower hepatic fatty acid synthase activity.

    • Selon Yasni S (1991)

      Extrait xanthorrhiza decreased the concentrations of serum triglycerides and phospholipids, and liver cholesterol, and increased serum HDL-cholesterol and apo A-I. xanthorrhiza on serum & liver lipids, serum high density lipoprotein (HDL)-cholesterol and apolipoprotein (apo) A-I, & liver lipogenic enzymes in rats.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.

Évolution de cette fiche publique

Sous le CTA · journal des mises à jour

Contenu

+2 indications · ~4 indications corrigées · +9 synergies · ~ posologie vétérinaire · +4 références

Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes des références ajoutées, corrigées ou retirées sont ci-dessous.

+2 indications~4 indications corrigées+9 synergies~ posologie vétérinaire+4 références
+4 références — afficher les textes
Aspamufita N et al, Efek ekstrak etanol rimpang temulawak (curcuma xanthorrhiza Roxb) terhadap memori spasial tikus model demensia yang diinduksi trimethyltin. Pharm, 3(2) : 2013-Abstract : Curcuma xaAspamufita N · 2013

Aspamufita N et al, Efek ekstrak etanol rimpang temulawak (curcuma xanthorrhiza Roxb) terhadap memori spasial tikus model demensia yang diinduksi trimethyltin. Pharm, 3(2) : 2013-Abstract : Curcuma xanthorrhiza Roxb is one of the plants containing curcumin. Curcumin has anti-amyloidogenic, antioxidant, & anti-inflammatory activity that can prevent dementia. The aim of the research was to know the effect of CX rhizome ETOH extract (CREE) to spatial memory on dementia model rat induced by trimethyltin (TMT). This research uses 30 rats, divided into 6 groups, each group consisted of 5 rats. Al…

Ajoutée
HARTANI D, THE PHARMACOGNOSTIC STANDARDS, ANTIOXIDANT ACTIVITY, & HEPATIC SAFETY PROFILE OF AN INDONESIAN ANTIDIABETIC POLYHERBAL FORMULATION, Indonesian Jl of Pharm, 2022-Abstract: This study evaluatHARTANI D · 2022

HARTANI D, THE PHARMACOGNOSTIC STANDARDS, ANTIOXIDANT ACTIVITY, & HEPATIC SAFETY PROFILE OF AN INDONESIAN ANTIDIABETIC POLYHERBAL FORMULATION, Indonesian Jl of Pharm, 2022-Abstract: This study evaluated the selected pharmacognostic characters, antioxidant activities, total phenolic content, & the hepatic safety of a polyherbal formulation containing seven plant constituents used by Klinik Wisata Kesehatan Jamu Kalibakung, Tegal, Indonesia, to treat diabetes patients. The pharmacognostic properties of the formulation were characterized according to the WHO quality control methods for herbal …

Ajoutée
SU JY et al, Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil & Zedoary Turmeric Oil in vivo, SU JY · 2012

SU JY et al, Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil & Zedoary Turmeric Oil in vivo, Jl of Ethnopharmacol, 141(2):608-14. 2012-Abstract: Chrysanthemum indicum (Compositae) Linné, Pogostemon cablin (Blanco) Benth & Curcuma wenyujin (Zingiberaceae) Y. H. Chen et C. Ling are three of the extensively used herbal remedies among traditional Chinese medicines for the purpose of anti-inflammation. A traditional Chinese medicine (TCM) recipe named CPZ consisting extracts of the above th…

Ajoutée
ALIPIN K et al, The Potential of Combined Curcuma xanthorrhiza Rhizome & Averrhoa bilimbi Fruit Extract on Decreasing Blood Glucose Levels, Insulitis Degree & Liver Structure Repair of Diabetic Male WALIPIN K · 2019

ALIPIN K et al, The Potential of Combined Curcuma xanthorrhiza Rhizome & Averrhoa bilimbi Fruit Extract on Decreasing Blood Glucose Levels, Insulitis Degree & Liver Structure Repair of Diabetic Male Wistar Rats Streptozotocin Induced, JL of Diabetes & Metabolism, 10:10, 2019-Abstract: Curcuma xanthorrhiza Roxb. rhizomes & Averrhoa bilimbi L. fruits have been potential as anti-diabetic herbs. Diabetes mellitus (DM) is a metabolic disorder characterized by high blood glucose levels or hyperglycemia due to deficiency or ineffectiveness of insulin. The combined use of natural herb (polyherbal) …

Ajoutée

Par Emmanuel Nossin · ethnopharmacologue

Contenu

+2 indications · ~1 indication corrigée · +2 synergies · +4 références

Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes complets des références ajoutées, corrigées ou retirées sont ci-dessous.

+2 indications~1 indication corrigée+2 synergies+4 références
+4 références — afficher les textes
Aspamufita N et al, Efek ekstrak etanol rimpang temulawak (curcuma xanthorrhiza Roxb) terhadap memori spasial tikus model demensia yang diinduksi trimethyltin. Pharm, 3(2) : 2013-Abstract : Curcuma xaAspamufita N · 2013

Aspamufita N et al, Efek ekstrak etanol rimpang temulawak (curcuma xanthorrhiza Roxb) terhadap memori spasial tikus model demensia yang diinduksi trimethyltin. Pharm, 3(2) : 2013-Abstract : Curcuma xanthorrhiza Roxb is one of the plants containing curcumin. Curcumin has anti-amyloidogenic, antioxidant, & anti-inflammatory activity that can prevent dementia. The aim of the research was to know the effect of CX rhizome ETOH extract (CREE) to spatial memory on dementia model rat induced by trimethyltin (TMT). This research uses 30 rats, divided into 6 groups, each group consisted of 5 rats. Al…

Ajoutée
HARTANI D, THE PHARMACOGNOSTIC STANDARDS, ANTIOXIDANT ACTIVITY, & HEPATIC SAFETY PROFILE OF AN INDONESIAN ANTIDIABETIC POLYHERBAL FORMULATION, Indonesian Jl of Pharm, 2022-Abstract: This study evaluatHARTANI D · 2022

HARTANI D, THE PHARMACOGNOSTIC STANDARDS, ANTIOXIDANT ACTIVITY, & HEPATIC SAFETY PROFILE OF AN INDONESIAN ANTIDIABETIC POLYHERBAL FORMULATION, Indonesian Jl of Pharm, 2022-Abstract: This study evaluated the selected pharmacognostic characters, antioxidant activities, total phenolic content, & the hepatic safety of a polyherbal formulation containing seven plant constituents used by Klinik Wisata Kesehatan Jamu Kalibakung, Tegal, Indonesia, to treat diabetes patients. The pharmacognostic properties of the formulation were characterized according to the WHO quality control methods for herbal …

Ajoutée
SU JY et al, Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil & Zedoary Turmeric Oil in vivo, SU JY · 2012

SU JY et al, Experimental study on anti-inflammatory activity of a TCM recipe consisting of the supercritical fluid CO2 extract of Chrysanthemum indicum, Patchouli Oil & Zedoary Turmeric Oil in vivo, Jl of Ethnopharmacol, 141(2):608-14. 2012-Abstract: Chrysanthemum indicum (Compositae) Linné, Pogostemon cablin (Blanco) Benth & Curcuma wenyujin (Zingiberaceae) Y. H. Chen et C. Ling are three of the extensively used herbal remedies among traditional Chinese medicines for the purpose of anti-inflammation. A traditional Chinese medicine (TCM) recipe named CPZ consisting extracts of the above th…

Ajoutée
ALIPIN K et al, The Potential of Combined Curcuma xanthorrhiza Rhizome & Averrhoa bilimbi Fruit Extract on Decreasing Blood Glucose Levels, Insulitis Degree & Liver Structure Repair of Diabetic Male WALIPIN K · 2019

ALIPIN K et al, The Potential of Combined Curcuma xanthorrhiza Rhizome & Averrhoa bilimbi Fruit Extract on Decreasing Blood Glucose Levels, Insulitis Degree & Liver Structure Repair of Diabetic Male Wistar Rats Streptozotocin Induced, JL of Diabetes & Metabolism, 10:10, 2019-Abstract: Curcuma xanthorrhiza Roxb. rhizomes & Averrhoa bilimbi L. fruits have been potential as anti-diabetic herbs. Diabetes mellitus (DM) is a metabolic disorder characterized by high blood glucose levels or hyperglycemia due to deficiency or ineffectiveness of insulin. The combined use of natural herb (polyherbal) …

Ajoutée

Par Emmanuel Nossin · ethnopharmacologue

Contenu

+1 indication · −1 indication · +1 synergie · +4 références · −4 références

Compteurs et domaines uniquement : les libellés d’indications et les noms de synergies ne sont pas publiés ici (ouvrir la fiche dans l’application). Les textes des références ajoutées, corrigées ou retirées sont ci-dessous.

+1 indication−1 indication+1 synergie+4 références−4 références
+4 références — afficher les textes
DEVARAJ S et al, Evaluation of the hepatoprotective activity of standardized ethanolic extract of Curcuma xanthorrhiza Roxb, J of Med Plants Res, 4(23) :2512-7, 2010-Abstract: Curcuma xanthorrhiza is DEVARAJ S · 2010

DEVARAJ S et al, Evaluation of the hepatoprotective activity of standardized ethanolic extract of Curcuma xanthorrhiza Roxb, J of Med Plants Res, 4(23) :2512-7, 2010-Abstract: Curcuma xanthorrhiza is widely used in Indonesia folk medicine to treat liver disorders. This study has evaluated the hepatoprotective activity of standardized ethanolic extract of C. xanthorrhiza. The extract was standardized using GC-MS. The hepatoprotective activity of this extract was studied using ethanol- induced liver toxicity in rats. This respective activity was assessed through monitoring liver function tes…

Ajoutée
Devaraj S et al, Evaluation of the Antinociceptive Activity & Acute Oral Toxicity of Standardized Ethanolic Extract of the Rhizome of Curcuma xanthorrhiza Roxb, Molecules, 22 :15(4) :2925-34, 2010.-AbDevaraj S · 2010

Devaraj S et al, Evaluation of the Antinociceptive Activity & Acute Oral Toxicity of Standardized Ethanolic Extract of the Rhizome of Curcuma xanthorrhiza Roxb, Molecules, 22 :15(4) :2925-34, 2010.-Abstract: Ethanolic extract of Curcuma xanthorrhiza was used to evaluate the analgesic & toxicity effects in vivo. The extract was standardized using GC-MS, which showed that 1 mg of Curcuma xanthorrhiza ethanolic extract contains 0.1238 mg of xanthorrhizol. The Analgesic activity was studied in rats using three different models, namely the hot plate test, tail flick test and formalin-induced pai…

Ajoutée
YASNI S et al, Effects of C. Xanthorryza & curcuminoids on the level of serum & lever lipids, serum apolipoprotein A-1 & lipogenic enzymes in rats, Food Chem Toxicol, 31(3) :213-8, 1993.YASNI S · 1993

YASNI S et al, Effects of C. Xanthorryza & curcuminoids on the level of serum & lever lipids, serum apolipoprotein A-1 & lipogenic enzymes in rats, Food Chem Toxicol, 31(3) :213-8, 1993.

Ajoutée
Yasni S et al, Dietary Curcuma xanthorrhiza Roxb. increases mitogenic responses of splenic lymphocytes in rats, & alters populations of the lymphocytes in mice, J Nutr Sci Vitaminol (Tokyo), 1993,39(4Yasni S · 1993

Yasni S et al, Dietary Curcuma xanthorrhiza Roxb. increases mitogenic responses of splenic lymphocytes in rats, & alters populations of the lymphocytes in mice, J Nutr Sci Vitaminol (Tokyo), 1993,39(4):345-54-Abstract: rhizomes of Curcuma xanthorrhiza Roxb, a medicinal plant in Indonesia, has been shown to exert diverse physiological functions. Hitherto, a little attention has been paid to its effect on immune functions. This study was carried out to determine the effect of this medicinal plant on mitogenic response of splenic lymphocytes in rats & population of splenic lymphocytes & macro…

Ajoutée
YASNI S et al, Effects of C. Xanthorryza & curcuminoids on the level of serum & lever lipids, serum apolipoprotein A-1 & lipogenic enzymes in rats, Food Chem Toxicol, 31(3) :213-8, 1993.YASNI S · 1993

YASNI S et al, Effects of C. Xanthorryza & curcuminoids on the level of serum & lever lipids, serum apolipoprotein A-1 & lipogenic enzymes in rats, Food Chem Toxicol, 31(3) :213-8, 1993.

Retirée
DEVARAJ S et al, Evaluation of the hepatoprotective activity of standardized ethanolic extract of Curcuma xanthorrhiza Roxb, J of Med Plants Res, 4(23) :2512-7, 2010-Abstract: Curcuma xanthorrhiza is DEVARAJ S · 2010

DEVARAJ S et al, Evaluation of the hepatoprotective activity of standardized ethanolic extract of Curcuma xanthorrhiza Roxb, J of Med Plants Res, 4(23) :2512-7, 2010-Abstract: Curcuma xanthorrhiza is widely used in Indonesia folk medicine to treat liver disorders. This study has evaluated the hepatoprotective activity of standardized ethanolic extract of C. xanthorrhiza. The extract was standardized using GC-MS. The hepatoprotective activity of this extract was studied using ethanol- induced liver toxicity in rats. This respective activity was assessed through monitoring liver function tes…

Retirée
Devaraj S et al, Evaluation of the Antinociceptive Activity & Acute Oral Toxicity of Standardized Ethanolic Extract of the Rhizome of Curcuma xanthorrhiza Roxb, Molecules, 22 :15(4) :2925-34, 2010.-AbDevaraj S · 2010

Devaraj S et al, Evaluation of the Antinociceptive Activity & Acute Oral Toxicity of Standardized Ethanolic Extract of the Rhizome of Curcuma xanthorrhiza Roxb, Molecules, 22 :15(4) :2925-34, 2010.-Abstract: Ethanolic extract of Curcuma xanthorrhiza was used to evaluate the analgesic & toxicity effects in vivo. The extract was standardized using GC-MS, which showed that 1 mg of Curcuma xanthorrhiza ethanolic extract contains 0.1238 mg of xanthorrhizol. The Analgesic activity was studied in rats using three different models, namely the hot plate test, tail flick test and formalin-induced pai…

Retirée
Yasni S et al, Dietary Curcuma xanthorrhiza Roxb. increases mitogenic responses of splenic lymphocytes in rats, & alters populations of the lymphocytes in mice, J Nutr Sci Vitaminol (Tokyo), 1993,39(4Yasni S · 1993

Yasni S et al, Dietary Curcuma xanthorrhiza Roxb. increases mitogenic responses of splenic lymphocytes in rats, & alters populations of the lymphocytes in mice, J Nutr Sci Vitaminol (Tokyo), 1993,39(4):345-54-Abstract: rhizomes of Curcuma xanthorrhiza Roxb, a medicinal plant in Indonesia, has been shown to exert diverse physiological functions. Hitherto, a little attention has been paid to its effect on immune functions. This study was carried out to determine the effect of this medicinal plant on mitogenic response of splenic lymphocytes in rats & population of splenic lymphocytes & macro…

Retirée

Par Emmanuel Nossin · ethnopharmacologue

Contenu

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Par Emmanuel Nossin · ethnopharmacologue