Cyperus rotundus (Koko-chat) : vertus médicinales en extraction alcoolique

Cyperus rotundus (Koko-chat, Ti-Vensan, Chien-Kôk, Coco-à-chat, Petit Vincent, Chien-coq, Koko-cat, Little Vincent) — famille Cypéracées.

Synonymes scientifiques : Cyperus purpurea variegatus-Böcklr. C hexastachyus-Roxb. C hydra-Michx..

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 33 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 118 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome buccal, colorectal, hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Xue BX (2023)

     Extrait Their pharmacological effects on the digestive system, nervous system, gynecological diseases, & other bioactivities like antioxidant, anti-inflammatory, anti-cancer, insect repellent, anti-microbial activity, etc. In traditional Chinese medicine (TCM), its rhizomes are frequently used to treat liver disease, stomach pain, breast tenderness, dysmenorrheal & menstrual irregularities.

   • Selon Gurusamy K (2010)

     Extrait The ethanolic extracts of the polyherbal medicinal plants (Asteracantha longifolia, Cyperus rotundus & Bryophyllum pinnatum) were evaluated for hepatoprotective activity in carbon tetrachloride induced liver damage in rats. exhibited a significant protective effect by lowering serum and liver activities of aspartate transaminase (AST), alanine transaminase (ALT), acid phosphatase (ACP), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), serum Bilirubin, serum cholesterol & serum total protein when compared with standard silymarin.

   • Selon DHANYA NV (2017)

     Extrait The present study was carried out to investigate the in vitro anticancer potential of ethanol extract of the rhizome of Cyperus rotundus in KB oral cancer cell lines. All these results establish the effect of CR as a potent anticancer agent against oral cancer cell lines.

   • Selon Nidugala H (2016)

     Extrait This study was designed to investigate the in vitro anticancer potential of aqueous & ethanol extracts of Cyperus rotundus (L.). Nidugala H et al, in vitro cytotoxic activity of rhizome extracts of Cyperus rotundus (L.) against colon Carcinoma and Ehrlich ascites Carcinoma.

   • Selon Suryawanshi S (2019)

     Extrait Aim of the study: The present study is aimed at evaluating the anticancer activity of the polyherbal formulation (HC9) & its mechanism of action against breast cancer cell lines. Cyperus rotundus L., Zingiber officinale Roscoe, Cedrus deodara (Roxb.

2. 2

   Diabète mellitus de type II

   Partie usitée : Rhizome.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Raut Na (2012)

     Extrait Traditional systems of medicine reported the use of Cyperus rotundus in the treatment of diabetes. These fractions were screened for antidiabetic activity using alloxan induced diabetes in rats.

   • Selon Raut NA (2006)

     Extrait In light of the traditional claim of C rotundus in the treatment of diabetes, investigations were carried out to evaluate its effect on alloxan induced hyperglycemia in rats.

   • Selon Kabbashi AS (2015)

     Extrait rotundus whole plant ethanol extract which exhibited 100% mortality within 96 h, at a concentration 500 ppm; this was compared with Metronidazole which gave 96% inhibition at concentration 312.5 µg/ml at the same time In addition cytotoxicity (MTT assay) with different concentration (500, 250 & 125 ppm) in comparison to triton-x100 (the reference control) which verified the safety of the examined extract with an IC50 less 100 µg/ml. (Family: Cyperaceae), has a number of pharmacological and biological activities including anti-inflammatory, antidiabetic, antidiarrhoeal, cytoprotective, antimutagenic, antimicrobial, antioxidant, cytotoxic and apoptotic, anti-pyretic & analgesic activities.

   • Selon Nagaraj Kanagali S (2021)

     Extrait The present study aimed to evaluate the interaction of reported bioactives from Cyperus rotundus against obesity via network pharmacology & to evaluate the efficacy of hydroalcoholic extract of CR against the olanzapine-induced weight gain & metabolic disturbances in experimental animals. During treatment, body weight & food intake were recorded; after the successful completion of 21 days of treatment, animals were fasted to perform oral glucose & insulin tolerance tests.

3. 3

   Hépatite B, cirrhose, stéatose hépatique

   Partie usitée : Rhizome.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Xue BX (2023)

     Extrait In traditional Chinese medicine (TCM), its rhizomes are frequently used to treat liver disease, stomach pain, breast tenderness, dysmenorrheal & menstrual irregularities.

   • Selon Gurusamy K (2010)

     Extrait The ethanolic extracts of the polyherbal medicinal plants (Asteracantha longifolia, Cyperus rotundus & Bryophyllum pinnatum) were evaluated for hepatoprotective activity in carbon tetrachloride induced liver damage in rats. exhibited a significant protective effect by lowering serum and liver activities of aspartate transaminase (AST), alanine transaminase (ALT), acid phosphatase (ACP), alkaline phosphatase (ALP), lactate dehydrogenase (LDH), serum Bilirubin, serum cholesterol & serum total protein when compared with standard silymarin.

   • Selon AL-MASSARANI SHAZA (2016)

     Extrait AL-MASSARANI SHAZA et al, Composition & biological activity of Cyperus rotundus L tuber volatiles from Saudi Arabia, Natural Volatiles & Essential Oils, 3’2) :2016.Abstract The present study was conducted to investigate the composition of the oïl of Cyperus rotundus L. The essential oïl recovered with diethyl ether demonstrated potent cytotoxic activities against colon (HCT-116), hepatocellular (Hep G-2) & breast (MCF-7) human cancer cell lines with IC50s of 1.06, 1.17 & 2.22 µg/mL, respectively.

   • Selon Oladunni OM (2011)

     Extrait The present study was undertaken to investigate the physicochemical properties of the oil, mineral & nutritional compositions of Cyperus rotundus (nut of nut grass).

   • Selon Babiaka SB (2021)

     Extrait Since 1965, a total of about 192 compounds including terpenoids, flavonoids, stilbenes, aromatics & aliphatic fatty acids have been characterized. (Nutgrass, family Cyperaceae) is a notorious weed which is widespread in temperate tropical & subtropical regions of the world.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.