Cytrus hystrix (Combava) : vertus médicinales en extraction alcoolique

Cytrus hystrix (Combava, Kaffir lime) — famille Rutacées.

Synonymes scientifiques : Citrus micranta-W, Fortunella sagittifolia-F & M.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 13 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 118 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Hépatopathie & cardiopathie induite par la Doxorubicine

   Partie usitée : Fruit.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Pallavi M (2021)

     Extrait Remarkably, lime peel extract followed by sour orange & orange at 500 mg kg-1 dose improved hepatic architecture to near normal with less deposition of fat globules & fewer sinusoids.

   • Selon Arumugam A (2015)

     Extrait On the 7th day animals were sacrificed & liver function markers (ALT, AST, ALP), total bilirubin & total protein in blood serums & hepatic antioxidants (SOD, CAT, GSH & GPx) in liver homogenate were estimated. The leaf extracts restored the liver function markers & hepatic antioxidants to the normal level than elevated levels noticed on paracetamol control at p < 0.001.

   • Selon Putri H (2013)

     Extrait ChEE repaired cardiohistopathology profile of doxorubicin induced cardiotoxicity & hepatotoxicity rats, but did not repair neither hepatohisto-pathology profile nor reduce serum activity of ALT & AST. To observe the combination effect of doxorubicin & Citrus hystrix (kaffir lime's) peel ethanolic extract (ChEE) on blood serum alanine aminotransferase (ALT) & aspartate aminotransferase (AST) activity & cardio-hepato-histopathology of female Sprague Dawley rats.

   • Selon Ishak M (2020)

     Extrait This study aims to investigate the efficacy of Citrus hystrix leaf extract (CLE) in alleviating CAC.

   • Selon Dertyasasa (2017)

     Extrait : Previous studies have reported that a number of organic compounds are present in kaffir lime (Citrus hystrix DC.) leaf extracts.

2. 2

   Infection bacterienne : Escherichia colo, Staphylococcus aureus, Salmonella Typhimurium, Pseudomonas aeruginosa

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Arumugam A (2012)

     Extrait The microorganisms used include Staphylococcus aureus (MTCC 3160), Salmonella typhi (MTCC 3215), Escherichia coli (MTCC 40), Pseudomonas aeruginosa (MTCC 424), Klebsiella pneumoniae (MTCC 3384). Since plants are used as therapeutic agents, the present study was conducted to evaluate the antibacterial activities of methanolic extracts of different components of Citrus hystrix & Citrus maxima ( Red & White) fruit.

   • Selon Nendissa SJ (2021)

     Extrait To support its use and increase its application in supporting food safety, a test the inhibition of on kaffir lime leaf extract against pathogenic bacteria, namely Gram Negative Bacteria (Escherichia coli, Salmonella typhimurium ) & Gram Positive bacteria ( Staphylococcus aereus, P. The antibacterial activity of CH leaf extract was tested by diffusion method using disc paper to determine of the bacterial growth inhibition area.

   • Selon Srisukh Vimol (2012)

     Extrait The antibacterial activities were tested by disc-diffusion & broth microdilution methods against 411 isolates of groups A, B, C, F, G streptococci, Streptococcus pneumoniae, Haemophilus influenzae, Staphylococcus aureus (methicillin-resistant & -sensitive S. Citrus hystrix DC, or makrut lime, contains two essential oils, makrut leaf oil & makrut (fruit peel) oil, of which we determined the inhibitory effect against respiratory pathogens & evaluated their active components.

   • Selon Othman (2016)

     Extrait hystrix essential oil has been experimentally shown to have antimicrobial & antifeedant activities, while no bioactivity study has been reported on the essential oils of other Malaysian Citrus species.

   • Selon DOREEN SH (2011)

     Extrait A study was conducted to evaluate the antibacterial activities of the emulsions containing essential oil of Kaffir lime, Citrus hystrix. Emulsion with surfactant mixture of Tween 80 & Span 80 at the ratio of 90:10 with 2% essential oil had the most effective antibacterial properties.

3. 3

   Colite associée au carcinome colorectal

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ishak M (2020)

     Extrait Patients with IBD are associated with high risk of colorectal cancer (CRC), namely, colitis associated cancer (CAC). Thus, CLE effect on colitis associated cancer was further investigated in an animal model to see how the body respond to CLE absorption in the body of mice.

   • Selon Abelmaesoomi M (2022)

     Extrait In this study, the antioxidant activities of hexane, ethyl acetate, methanol & water extracts of CH leaves & their growth inhibitory effects on colorectal (HCT 116) & breast cancer (MCF 7, MDA-MB 231 & HCC 1937) cells were analysed. However, information on breast & colorectal cancer is limited especially the mechanistic aspects.

   • Selon Wijayanti N (2015)

     Extrait The objective of this research was to determine the cytotoxicity effect & apoptosis induced by leaves extract CH to cervical cancer cell line (HeLa cells). Leaves of CH contain of polyphenols & essential oils thus they were possibly cytotoxic to cancer cell line.

   • Selon Ho Y (2020)

     Extrait This study aimed to evaluate the anticancer properties of CH leaf extract & its bioactive constituents citronellol & citronellal against the triple negative breast cancer MDA-MB-231 cell line. The in vitro anticancer effects of CH leaf extracts, & its bioactive constituents (citronellol & citronellal) were evaluated against MDA-MB-231 cell line using cytotoxic MTT assay, cell proliferation, wound scratch migration, colony formation, cell cycle, apoptosis assay, Hoechst staining, RT-qPCR, & Western blot analysis.

   • Selon Tunjung WAS (2015)

     Extrait These data showed that CH extract reduces the viability of cervical & neuroblastoma cell lines & may have potential as anti-cancer compounds. The objective of this study was to examine the cytotoxic effect of CH leaf extract on cervical cancer & neuroblastoma cell lines.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.