Datura innoxia (Gwo-Konkonb-chien) : vertus médicinales en extraction alcoolique

Datura innoxia (Gwo-Konkonb-chien, Gwo-konkonb- djab, Gros-concombre-à-chien, Gros-concombre-à-diable, Trompette du Jugement, Large dog-cucumber, Large devil-cucumber, Trumpet of Judgement) — famille Solanacées.

Synonymes scientifiques : Brugmansia waymanni-Paxton, Datura humilis-dest, D metel-L, D meteloides-DC ex Dunal, D Wagmanii-Steud.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 42 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Infection bactérienne : E scherrichia coli, Bacillus anthracoides

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Kaushik P (2008)

     Extrait Various parts of Datura innoxia were examined for potential antibacterial activity by preparing their crude aqueous & organic extracts against Gram-negative bacteria (Escherichia coli & Salmonella typhi) & Gram-positive bacteria (Bacillus cereus, Bacillus subtilis & Staphylococcus aureus). The study promises an interesting future for designing a potentially active antibacterial agent from Datura innoxia.

   • Selon Effekthar F (2005)

     Extrait The antibacterial activity of the methanol extracts of the aerial parts of the Datura innoxia & Datura stramonium was investigated. Little or no antibacterial activity was found against Escherichia coli & Pseudomonas aeruginosa.

   • Selon Garaev EA (2021)

     Extrait The antimicrobial activity of plant oils of seed & ethanolic extracts of some parts (roots, stems, leaves, flowers, fruits & seeds) were studied on Staphylococcus aureus, Esherichia coli, Pseudomonas aeruginosa, Bacillus anthracoides, Klebsiella pneumoniae & Candida albicans. The purpose of the investigation is to study non-alkaloidal biological active compounds of various organs, the antimicrobial activity of plant oil & ethanolic extracts of Datura innoxia from nightshades (Solanaceae).

   • Selon Shama AI (2014)

     Extrait The aim of this study was evaluated the Antimicrobial Activity of extraction of Datura innoxia (Seeds, leaves & roots). Extracts of methanol, & aqueous of seeds, leaves & roots were prepared & tested against four types of bacteria namely: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa & Proteus vulgaris & two types of fungi namely: Aspergillus niger & Candida albicans.

   • Selon Tandon P (2016)

     Extrait The ethanol, hexane & aqueous leaf extracts of Datura inoxia were screened for their antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa & Escherichia coli. All extracts showed inhibitory effect against Staphylococcus aureus & Escherichia coli, while no inhibitory effect was found by aqueous & hexane extracts against Pseudomonas aeruginosa.

2. 2

   Cancer : traitement adjuvant du carcinome colorectal

   Partie usitée : Parties aeriennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Vermillion K (2011)

     Extrait Extracts and the purified compound were tested for their antiproliferative activities toward a panel of human normal & cancer cell lines. A new withanolide, Dinoxin B (12,21-dihydroxy-1-oxowitha-2,5,24-trienolide-27-O-β-d-glucopyranoside, 1), was isolated from a methanol extract of Datura inoxia leaves, using Bioassay-guided fractionation.

   • Selon Cheshomi H (2016)

     Extrait The present study was conducted to evaluate the cytotoxic effects of the methanolic extracts of Datura innoxia petals, native to central & South America & distributed in Africa, Asia, Australia, & Europe, on the breast cancer cell line (MCF-7). Conclusions: These findings indicate that the methanolic extracts of DI petals can act as a possible food supplement with anticancer effects & can be used after complementary tests,.

   • Selon Al-Zharani (2021)

     Extrait The cell viability study revealed that the ethanolic extract of DI demonstrated potent cytotoxicity, with a 50-IC value of 10 μg/mL against LoVo colon cancer cells. innoxia on various cancer cell proliferation.

   • Selon Arul Vasu C (2010)

     Extrait In the present study, we investigated the effects of methanolic leaf extracts from Datura innoxia, on the growth of human colon adenocarcinoma (HCT 15) & human larynx cancer cell lines (Hep-2). These herbal preparations alleged to have many biological activities, such as stimulation or suppression of immune responses & antiproliferative effects on cancer cells.

   • Selon BABU G (2019)

     Extrait Thus, this study reveals that the green synthesis is an ecofriendly method for production of AgNPs from Datura inoxia flower extract which provided a powerful anti-proliferative action on MCF7 cell line, suggesting them as a novel chemotherapeutic agent against human breast cancer. The silver nanoparticles (AgNPs) were synthesized biologically through a green synthesis method using the flower extract of Datura inoxia, a well-known medicinal plant for its antispasmodic, pacifying, pain relief, and for respiratory ailments.

3. 3

   Infection : bacterienne: Staphylococcus-aureus, Methicilline -résistante

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Kaushik P (2008)

     Extrait Various parts of Datura innoxia were examined for potential antibacterial activity by preparing their crude aqueous & organic extracts against Gram-negative bacteria (Escherichia coli & Salmonella typhi) & Gram-positive bacteria (Bacillus cereus, Bacillus subtilis & Staphylococcus aureus). The study promises an interesting future for designing a potentially active antibacterial agent from Datura innoxia.

   • Selon Effekthar F (2005)

     Extrait The antibacterial activity of the methanol extracts of the aerial parts of the Datura innoxia & Datura stramonium was investigated. Little or no antibacterial activity was found against Escherichia coli & Pseudomonas aeruginosa.

   • Selon George R (2021)

     Extrait Conclusion: Dinoxin B with its bactericidal properties & significant affinity towards Quorum-signaling Sar A protein & Penicillin Binding Protein can be considered as an effective bioactive compound against Methicillin Resistance Staphylococcus aureus. Objective: This research has focused to evaluate the efficacy of Dinoxin B Withanolide against infectious Staphylococcus aureus, including resistant strains.

   • Selon Garaev EA (2021)

     Extrait The antimicrobial activity of plant oils of seed & ethanolic extracts of some parts (roots, stems, leaves, flowers, fruits & seeds) were studied on Staphylococcus aureus, Esherichia coli, Pseudomonas aeruginosa, Bacillus anthracoides, Klebsiella pneumoniae & Candida albicans. The purpose of the investigation is to study non-alkaloidal biological active compounds of various organs, the antimicrobial activity of plant oil & ethanolic extracts of Datura innoxia from nightshades (Solanaceae).

   • Selon Shama AI (2014)

     Extrait The aim of this study was evaluated the Antimicrobial Activity of extraction of Datura innoxia (Seeds, leaves & roots). Extracts of methanol, & aqueous of seeds, leaves & roots were prepared & tested against four types of bacteria namely: Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa & Proteus vulgaris & two types of fungi namely: Aspergillus niger & Candida albicans.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.