Diodia sarmentosa (Lyenn-makônnèt) : vertus médicinales en extraction alcoolique

Diodia sarmentosa (Lyenn-makônnèt, Lyenn-razié, Liane -à-cornette, Liane-à-halliers) — famille Rubiacées.

Synonymes scientifiques : Diodia riparia -Sagot, D scandens-Benth, Spermacoce spinosa -Loefl, S aspera-Aubl.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 7 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 18 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome-hépatique

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Okoroafor FE (2024)

     Extrait It evaluated the biochemical, antioxidant, & anti-tumour potentials of the DS leaf extract on diethylnitrosamine-induced hepatocellular carcinoma in adult albino Wistar rats. This is the first in vivo study on the anti-cancer activities of Diodia sarmentosa leaves.

   • Selon Okoroafor FE (2019)

     Extrait This research aimed at studying the biochemical, antioxidant & anti-tumorigenic potentials of the ethanol extract of Diodia sarmentosa on Uterine Leiomyoma, Benign Prostatic Hyperplasia & Hepatocellular carcinoma in adult albino Wistar rats. Benign Prostatic Hyperplasia was induced by daily subcutaneous injection of 10 mg/kg body weight of testosterone propionate for 28 days & Hepatocellular carcinoma was induced by oral administration of 20 mg/kg body weight of diethyl nitrosamine (DEN) dissolved in normal saline (0.9%) < given 5 times a week for 6 weeks.

   • Selon Okoroafor FE (2024)

     Extrait It evaluated the biochemical, antioxidant, & anti-tumour potentials of the DS leaf extract on diethylnitrosamine-induced hepatocellular carcinoma in adult albino Wistar rats. This is the first in vivo study on the anti-cancer activities of Diodia sarmentosa leaves.

   • Selon Ezejiofor TIN (2019)

     Extrait Biochemical & histopathological evidence of anticancer potentials of ethanolic leaves extract of Diodia sarmentosa (Sw) against diethyl nitrosamine-induced hepatocellular carcinoma in albino rats (Abstracts).

2. 2

   Diabete mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon ---Elechi NA (2020)

     Extrait This study has investigated the antidiabetic potential of the extracts of Diodia sarmentosa (Rubiaceae) leaves on alloxan induced diabetic Wistar rats. Diabetes was induced by the intraperitoneal injection of 120mg/kg body weight of alloxan monohydrate to the rats.

   • Selon Elechi NA (2020)

     Extrait This study has investigated the antidiabetic potential of the extracts of Diodia sarmentosa (Rubiaceae) leaves on alloxan induced diabetic Wistar rats. Diabetes was induced by the intraperitoneal injection of 120mg/kg body weight of alloxan monohydrate to the rats.

   • Selon OGHOGHO AI (2018)

     Extrait This study demonstrates the hypoglycaemic & anti-diabetic activity of the aqueous ethanol extract & ethylacetate fractions of DS in alloxan-induced diabetic rats. Diodia sarmentosa (Rubiaceae) commonly called tropical button weed, has been used locally in the treatment of diabetes.

   • Selon Ijomone OR (2018)

     Extrait This study demonstrates the hypoglycaemic & anti-diabetic activity of the aqueous ethanol extract & ethylacetate fractions of Diodia sarmentosa in alloxan-induced diabetic rats. Diodia sarmentosa (Rubiaceae) commonly called tropical button weed, has been used locally in the treatment of diabetes.

   • Selon Ezejiofor TIN (2020)

     Extrait This study investigated the Free radical scavenging & antioxidant potential of ethanolic leaf extract of Diodia sarmentosa on high fat fed wistar rats. Free radical scavenging & antioxidant potential of ethanolic leaf extracts of Diodia sarmentosa on high fat fed Wistar rats.

3. 3

   Stress oxydatif

   Partie usitée : Feuille.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon EZEJIOFIR TIN (2022)

     Extrait Conclusion: The ETOH extract of-DS eaves mitigated oxidative stress &< improved the impaired antioxidant system caused by uterine leiomyoma induction. Diodia sarmentosa leaves have gained application in the local treatment of certain ailments.

   • Selon OKORO CA (2025)

     Extrait This study explored the preliminary phytochemical composition, antioxidant properties, & Fourier transform infrared (FTIR) analysis of bioactive compounds in Diodia sarmentosa (DS) aerial parts 70% ethanol extract. Its extensive phytochemical profile, antioxidant efficacy & accompanying functional groups demonstrate its potential for managing ailments such as oxidative stress related diseases, warranting more research for potential pharmaceutical development & therapeutic applications,.

   • Selon Ezejiofor TIN (2020)

     Extrait This study investigated the Free radical scavenging & antioxidant potential of ethanolic leaf extract of Diodia sarmentosa on high fat fed wistar rats. Free radical scavenging & antioxidant potential of ethanolic leaf extracts of Diodia sarmentosa on high fat fed Wistar rats.

   • Selon KORIE SC (2021)

     Extrait Diodia sarmentosa (Sw) also known as Zimbabwe flora or Tropical button weed is a straggling or procumbent perennial herb that grows in evergreen forest, riverine vegetation & bush land. This study investigated the role of the ethanolic leaf extract of DS as a free radical scavenger, and an antioxidant in high fat diet fed Wistar rats.

   • Selon Okoroafor FE (2024)

     Extrait This is the first in vivo study on the anti-cancer activities of Diodia sarmentosa leaves. In the treated group, significant (P<0.05) improvements were recorded in the serum levels of glutathione peroxidase, superoxide dismutase, catalase, vitamin C, glutathione, & total antioxidant capacity compared to the positive control.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.