Dioscorea bulbifera (Koko-bourik) : vertus médicinales en extraction alcoolique

Dioscorea bulbifera (Koko-bourik, Adon, Coco-à-bourrique) — famille Dioscoréacées.

Synonymes scientifiques : Dioscorea anthropophagorum-A.Chev, D crispata-Roxb, D latifolia-Benth, D tamifolia-Salisb, D violacea-Baudon, Helmia bulbifera-(L.) Kunth, Polynome bulbifera -L.) Salisb.

Sources externes reconnues associées à cette monographie : TRAMIL.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 10 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 114 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : traitement adjuvant du carcinome colorectal, hépatique & sarcome

   Partie usitée : Tubercule.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Guan XR (s.d.)

     Extrait bulbifera is effective in treating a wide range of diseases, such as pharyngitis, goitre, pyogenic skin infections, orchitis & cancer. The possible reasons for its toxicity include the toxic effects of diosbulbin B & D on hepatocytes, the inhibition of antioxidant enzymes in liver mitochondria, & inhibition of enzymes that ordinarily metabolize the herb’s components.

   • Selon Chinko BC (2016)

     Extrait Key words; Dioscorea bulbifera, lipid profile,serum glucose, liver enzymes. The control group received distilled water while the experimental groups received hydromethanolic extracts of Dioscorea bulbifera at 20mg/kg, 50mg/kg and 100mg/kg.

   • Selon Wang J (2011)

     Extrait The present study was undertaken to investigate the gender-related liver injury induced by Dioscorea bulbifera, a traditional medicinal plant, in mice, & further explored its hepatotoxic chemical compound. Further, comparing the liver injury induced by Diosbulbin B isolated from DB with that induced by EF on the basis of chemical analysis for the amounts of Diosbulbin B in EF of DB, we found that Diosbulbin B could be the main hepatotoxic chemical compound in DB.

   • Selon Wang J (2010)

     Extrait Hepatic tissues were used to assay for the level of lipid peroxide (LPO), amounts of antioxidants such as glutathione, & activities of antioxidant-related enzymes for liver oxidative-antioxidative status in mice. Taken together, our results indicate that the EF contains the main toxic ingredients of DB rhizome, & the mechanism of hepatotoxicity induced by it may be due to liver oxidative stress injury in mice.

   • Selon Tan X (2003)

     Extrait To explore the liver-toxic fraction in Rhizoma of Dioscorea bulbifera. Direct bilirubin (DBil) & Glutamic-pyruvic transaminase (GPT) were examined, & liver index was measured.

2. 2

   Diabète mellitus de type II

   Partie usitée : Tubercule.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ghosh S (2012)

     Extrait Two plants with significant traditional therapeutic potential, namely, Gnidia glauca & Dioscorea bulbifera, were tested for their efficiency to inhibit α-amylase & α-glucosidase. bulbifera were sequentially extracted with petroleum ether, ethyl acetate, & methanol as well as separately with 70% ethanol.

   • Selon Chinko BC (2016)

     Extrait The control group received distilled water while the experimental groups received hydromethanolic extracts of Dioscorea bulbifera at 20mg/kg, 50mg/kg and 100mg/kg. The present study is aimed at studying the biochemical effects of hydromethanolic extract of Dioscorea bulbifera on biochemical parameter using Wistar rats.

   • Selon Ghosh S (2014)

     Extrait This is the first report of its kind that provides an intense scientific rationale for use of diosgenin as novel drug candidate for type II diabetes mellitus,. Herein we report the promises of Dioscorea bulbifera & its bioactive principle, diosgenin as novel α-amylase & α-glucosidase inhibitor.

   • Selon Maithili V (2011)

     Extrait Indian J Pharmacol 2011; 43:455-9-Objective: To evaluate the antidiabetic activity of ethanolic extract of Dioscorea alata in glucose loaded & alloxan induced diabetic rats. Maithili V et al, Antidiabetic activity of ethanolic extract of tubers of Dioscorea alata in alloxan induced diabetic rats.

   • Selon Eni Kalu S (2019)

     Extrait Aerial yam (Dioscorea bulbifera) is an indigenous plant grown by few for food. Information also has it that it is used by rural diabetes patients.

3. 3

   Rétinopathie diabétique

   Partie usitée : Tubercule.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ghosh S (2012)

     Extrait Two plants with significant traditional therapeutic potential, namely, Gnidia glauca & Dioscorea bulbifera, were tested for their efficiency to inhibit α-amylase & α-glucosidase. bulbifera were sequentially extracted with petroleum ether, ethyl acetate, & methanol as well as separately with 70% ethanol.

   • Selon Chinko BC (2016)

     Extrait The control group received distilled water while the experimental groups received hydromethanolic extracts of Dioscorea bulbifera at 20mg/kg, 50mg/kg and 100mg/kg. The present study is aimed at studying the biochemical effects of hydromethanolic extract of Dioscorea bulbifera on biochemical parameter using Wistar rats.

   • Selon Ghosh S (2014)

     Extrait This is the first report of its kind that provides an intense scientific rationale for use of diosgenin as novel drug candidate for type II diabetes mellitus,. Herein we report the promises of Dioscorea bulbifera & its bioactive principle, diosgenin as novel α-amylase & α-glucosidase inhibitor.

   • Selon Maithili V (2011)

     Extrait Indian J Pharmacol 2011; 43:455-9-Objective: To evaluate the antidiabetic activity of ethanolic extract of Dioscorea alata in glucose loaded & alloxan induced diabetic rats. Maithili V et al, Antidiabetic activity of ethanolic extract of tubers of Dioscorea alata in alloxan induced diabetic rats.

   • Selon Eni Kalu S (2019)

     Extrait Aerial yam (Dioscorea bulbifera) is an indigenous plant grown by few for food. Information also has it that it is used by rural diabetes patients.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.