Dodonea viscosa (Mang-lozèy) : vertus médicinales en extraction alcoolique

Dodonea viscosa (Mang-lozèy, Mangle-oseille) — famille Sapindacées.

Synonymes scientifiques : Dodonea ehrenbergii-Schdtl., Dodonea viscosa-(L)-Lacq..

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 19 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 102 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Feuille. Profil pharmacologique documenté : Glibenclamide-like.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Muthukumran P (2011)

     Extrait The different extracts of the Dodonaea viscosa were tested for anti-diabetic activity, by glucose tolerance test in normal rats & alloxan induced diabetic rats. In long term treatment of alloxan induced diabetic rats, the degree of protection was determined by measuring blood glucose, triglycerides, cholesterol & urea levels on 0,3,5,7 & 10th day.

   • Selon AHMAD M (2012)

     Extrait It is concluded from the study that aqueous: methanolic (70:30) extract of Dodonaea viscosa leaves exerts antihyperlipidemic & hepatoprotective effects in the alloxan-induced diabetic rabbits,. The present study was conducted to determine the antihyperlipidemic & hepatoprotective activity of Dodonaea viscosa leaves extracts in the alloxan-induced diabetic rabbits.

   • Selon Akhtar MS (2011)

     Extrait Antidiabetic folkloric use of Dodonaea (D.) viscosa leaves was evaluated in normal and alloxan-diabetic rabbits. In addition, synergistic hypoglycemic effects of oral intake of A-M extract (representing 500 mg/kg) along with different doses of insulin were studied in diabetic rabbits.

   • Selon Veerapur VP (2010)

     Extrait Veerapur VP et al, Antidiabetic effect of Dodonaea viscosa (L) Lacq aerial parts in high fructose-fed insulin resistance rats: A mechanism-based study, Indian J of Experimental Biol, 48, 2010, 800-10.

   • Selon Meenu I (2011)

     Extrait Meenu I et al, EVALUATION OF ANTIHYPERGLYCEMIC ACTIVITY OF DODONAEA VISCOSA LEAVES IN NORMAL & STZ-DIABETIC RATS, Inter J of Pharm & Pharmaceut Sci, 3 Suppl 3, 2011.

2. 2

   Troubles hépatiques : cirrhose, hépatite, fibrose hépatique

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shalaby N (2012)

     Extrait viscosa ethanol extract & two fractions were examined in vivo against liver fibrosis induced by CCl4 in rats. The work was extended to measure serum protein content & liver function enzymes; aspartate and alanine aminotransferases (AST and ALT), alkaline phosphatase (ALP) & gamma glutamyl transferase (GGT).

   • Selon AHMAD M (2012)

     Extrait The oral administration of aqueous: methanol (70:30) extract of the Dodonaea viscosa leaves significantly (P<0.01) decreased the raised parameters (triglyceride, total cholesterol & LDL-cholesterol) to normal values. It is concluded from the study that aqueous: methanolic (70:30) extract of Dodonaea viscosa leaves exerts antihyperlipidemic & hepatoprotective effects in the alloxan-induced diabetic rabbits,.

   • Selon Ali (2014)

     Extrait In the present study we investigated the hepatoprotective potential of the methanolic extract of the whole plant of DV & its ethyl acetate, aqueous, butanol & n-hexane fractions against carbon tetrachloride (CCl₄) induced hepatoxicity in rats. HPLC fingerprinting suggested that Hautriwaic acid present in the methanolic extract & its ethyl acetate, & aqueous fractions may be responsible for this hepatoprotective activity of DV which was confirmed by in vivo experiments,.

   • Selon Tong ZW (2021)

     Extrait The intake of DV extracts restored the level of hepatic enzymes (ALP, AST ALT, & Direct bilirubin), hematological parameters (RBCs, WBCs, & Platelets), total protein, & liver antioxidant enzymes (SOD, GPx, and CAT) after a decline in levels by CCL4. Dodonaea viscosa flowers are found to have a protective effect against oxidative stress produced by CCL4 in the liver, kidney, & spleen.

   • Selon CAO S (2009)

     Extrait 5 A southern Brazilian outbreak of acute hepatic insufficiency in which 14 dairy animals died after consumption of D viscosa has been reported. Liquid-liquid partitioning of a portion of an EtOH extract of the roots of D viscosa into hexane, CH2Cl2 & aqueous MeOH fractions indicated that the CH2Cl2 fraction (326.5 mg) was the most active fraction, with an IC50 value of 1.0 μg/mL.

3. 3

   Cancer : traitement adjuvant du carcinome mammaire

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Shafek RE (2015)

     Extrait The main objective of this present work is to find out good pharmacological activities in herbal source with their phytochemical study, which is aimed to investigate of 80% ethanolic extract of Dodonaea Viscosa flowers for their antioxidant, analgesic & cytotoxic activities. Its cytotoxic activity against breast carcinoma cell line (MCF7) showed IC50 19.4 μg/ml compared with the standard used (Cisplatin), which its IC50 is 5.48μg/ml.

   • Selon BREVET (s.d.)

     Extrait The invention disclosed herein relates to the use of an extract of Dodonaea viscosa in breast cancer therapy, either alone or in combination with other breast cancer therapies.

   • Selon Rehman S (2023)

     Extrait This study aimed to assess the anti-rheumatic potential of Dodonaea viscosa to evaluate its bioactive small molecules for their beneficial effects in the management of rheumatoid arthritis. viscosa (ethanol extract) had drug-like properties.

   • Selon CAO S (2009)

     Extrait Bioassay-guided fractionation of an EtOH extract obtained from the roots of the Madagascan plant Dodonaea viscosa led to the isolation of two new antiproliferative oleanane-type triterpenoid saponins, dodoneasides A and B (1 and 2). In this paper, we report the isolation, structure elucidation, & antiproliferative activity of two new triterpenoid saponins (1 & 2) obtained from the roots of D viscosa.

   • Selon Anandan M (2018)

     Extrait The gold Nanoparticles with distinct morphologies were synthesized using Dodonaea viscosa leaf extract in different polar/non polar solvents.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.