Echinacea purpurea (Échinacée pourpre) : vertus médicinales en extraction alcoolique

Echinacea purpurea (Échinacée pourpre, rudbeckie pourpre, Purple Echinacea, Purple rudbeckia) — famille Astéracées.

Synonymes scientifiques : Brauneria purpurea (L.) Britton, Echinacea serotina (Sweet) D. Don, Rudbeckia purpurea L. Helichroa purpurea (L.) R.

Sources externes reconnues associées à cette monographie : Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 14 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 125 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Diabète mellitus de type II

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Delorme D (2005)

     Extrait The NOD (non-obese diabetic) mouse is currently regarded as an excellent animal model of human Type 1 diabetes. Based on this hypothesis, & the fact that the herb, Echinacea, is a well demonstrated immunostimulant of NK cells in normal mice/humans, we aimed to investigate, in NOD mice, the effect of short term (days) & long term (months) daily dietary administration of Echinacea, on the absolute levels of NK cells, & five other classes of hemopoietic & immune cells, in the bone marrow and spleen.

   • Selon Chiou SY (2017)

     Extrait The extraction yield, total phenols, Caffeic acid derivatives (CAD), & antioxidant properties of 50% ethanolic Echinacea purpurea flower extract were determined. purpurea extract & CAD have good potential for managing hyperglycemia & hypertension.

   • Selon Aarland RC (2017)

     Extrait Materials & methods: Density, dry matter, phenols (Folin-Ciocalteu method), flavonoids (AlCl3method), alkylamides (GC-MS analysis), antioxidant capacity (DPPH a&ABTS methods), antiproliferative effect (SRB assay), anti-inflammatory effect (paw oedema assay, 11 days/Wistar rats; 0.4 mL/kg) & hypoglycaemic effect (33 days/Wistar rats; 0.4 mL/kg) were determined in three Echinacea extracts which were labelled as A, B & C (A, roots of Echinacea purpurea L. Moench; B, roots, leaves, flowers & seeds of Echinacea purpurea; C, aerial parts & roots of Echinacea purpurea & roots of Echinacea angustifolia DC).

   • Selon Mao CF (2018)

     Extrait Echinacea purpurea ethanol extract (EE) contains phenolic acid & isobutylamides had been proven to ameliorate diabetic complications. The results show that the nano-EE5 can improve hyperglycemia, insulin resistance, and plasma fibroblast growth factor 21 (FGF 21) resistance.

2. 2

   Viremie : virus influenza A virus strain H1N1 (PR8)

   Partie usitée : Parties aériennes. Association synergique mentionnée : association synergique avec HUMULUS LUPULUS-L (Fleur).

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Percaccio E (2023)

     Extrait Moreover, the immunomodulating properties of the mixture in murine macrophages against antioxidant & inflammatory stimuli & its antiviral efficacy against the PR8/H1N1 influenza virus were assayed. In the present study, we developed a mixture of two hydroalcoholic extracts from the aerial parts of Echinacea purpurea (L.) Moench (ECP) & the cones of Humulus lupulus L.

   • Selon Merali S (2003)

     Extrait Antifungal & anti-inflammatory activity of the genus Echinacea.

   • Selon Auteur (2012)

     Extrait Extracts of Echinacea purpurea (EP, purple Coneflower) have been used traditionally in North America for the treatment of various types of infections & wounds, & they have become very popular herbal medicines globally. Recent studies have revealed that certain standardized preparations contain potent & selective antiviral & antimicrobial activities.

   • Selon Binns SE (2002)

     Extrait Antiviral activity of characterized extracts from Echinacea spp. (Heliantheae: Asteraceae) against herpès simplex virus (HSV-I).

   • Selon Binns SE (2000)

     Extrait Light-mediated antifungal activity of Echinacea extracts.

3. 3

   Cancer : traitement adjuvant du carcinome colorectal

   Partie usitée : Fleur.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Tsai YL (2012)

     Extrait The aims of this study were to provide a preliminary validation of the effects of 50% aqueous ethanol extract of E purpurea flowers & its major compound, Chicoric acid, on human colon cancer cells Caco-2 & HCT-116. MATERIALS & METHODS: The cytotoxic effects of Echinacea flower extracts & Chicoric acid on cell viability, telomerase activity, DNA fragmentation, β-catenin, caspase-9, & cleavage of poly-ADP-ribose polymerase (PARP) of human colon cancer cell were examined.

   • Selon Lersch CM (1992)

     Extrait Two months after onset of therapy a partial tumor regression was documented in one and a stable disease in 6 other patients by abdominal ultrasonography, decrease of the tumor markers carcinoembryonic antigen (CEA), CA 19-9, CA 15-3, and/or chest roentgenography, which may also be attributed to the natural course of disease. Outpatients (n = 15) with metastasizing far advanced colorectal cancers received immunotherapy consisting of low-dose cyclophosphamide (LDCY) 300 mg/m2 every 28 days i.v.

   • Selon Mac-Cann DA (2007)

     Extrait PBMCs from vaccinated individuals were stimulated in vitro with Echinacea tinctures & influenza virus; cytokine production (IL-2, IL-10, & interferon-gamma [IFN-gamma]) was compared prevaccination & postvaccination. In the first set of experiments, PBMCs were stimulated in vitro with tinctures alone & assayed for proliferation & production of interleukin-10 (IL-10), IL-12, & tumor necrosis factor-alpha (TNF-alpha).

   • Selon Steinmuller C (1993)

     Extrait Polysaccharides (EP) isolated from large scale plant cell cultures of Echinacea purpurea, have been shown to activate human & murine phagocytes. EP-treated macrophages exhibited increased production of tumor necrosis factor-alpha (TNF) and enhanced cytotoxicity against tumor target WEHI 164 as well as against the intracellular parasite Leishmania enriettii.

   • Selon Aarland RC (2017)

     Extrait Materials & methods: Density, dry matter, phenols (Folin-Ciocalteu method), flavonoids (AlCl3method), alkylamides (GC-MS analysis), antioxidant capacity (DPPH a&ABTS methods), antiproliferative effect (SRB assay), anti-inflammatory effect (paw oedema assay, 11 days/Wistar rats; 0.4 mL/kg) & hypoglycaemic effect (33 days/Wistar rats; 0.4 mL/kg) were determined in three Echinacea extracts which were labelled as A, B & C (A, roots of Echinacea purpurea L. Moench; B, roots, leaves, flowers & seeds of Echinacea purpurea; C, aerial parts & roots of Echinacea purpurea & roots of Echinacea angustifolia DC).

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.