Eclipta alba (Podjak) : vertus médicinales en extraction alcoolique

Eclipta alba (Podjak, Kongo-Lala) — famille Astéracées.

Synonymes scientifiques : Cotula alba-L, Eclipta alba-(L)-Kuntze, E brachypoda-Michx, E erecta-L, E prostata-L, E punctata-L, Eupatoriophalacron album-(L)-Hitch, Verbesina alba-L, V prostata-L.

Sources externes reconnues associées à cette monographie : TRAMIL et Pharmacopée française.

Cette base documente les extractions alcooliques (éthanol) des substances actives. Notre monographie recense actuellement 31 indications en extraction alcoolique pour cette espèce. Le catalogue Lapo v2 enregistre 153 références scientifiques pour cette espèce (détail intégral dans l’application).

Important — références scientifiques sur cette page publique : seuls de courts extraits de chaque source citée sont présentés (phrases d’abstract sélectionnées), conservés dans leur langue d’origine (le plus souvent l’anglais), sans traduction. Ces extraits ne constituent pas le texte intégral de l’article ni une bibliographie complète. Les fiches de référence complètes et le détail monographique sont disponibles dans l’application Lapo v2 (essai gratuit 30 jours).

1. 1

   Cancer : chemoprevention du carcinome hépatique, renal, mammaire hormono-dépendant et du gliome, (action anti-métastasique)

   Partie usitée : Parties aériennes.

   Scientific references (short excerpts)

   Short excerpts only (not the full article). Full reference records are in the Lapo v2 application.

   • Selon Xia Y (2013)

     Excerpt The purpose of this study was to demonstrate the anti-fibrotic effects of wedelolactone on activated human hepatic stellate cell (HSC) line LX-2 & the possible underlying mechanisms by means of MTT assay, Hoechst staining, as well as real-time quantitative PCR & western blot. Wedelolactone is a major coumarin of Eclipta prostrata, which is used for preventing liver damage.

   • Selon Singh B (1993)

     Excerpt An alcoholic extract of freshly collected Eclipta alba exhibited dose-dependent (62.5–500.0 mg/kg p.o.) significant hepatoprotective activity against carbon tetrachloride-induced liver injury in rats & mice. K (2011) — extrait : Eclipta Alba is small branched annual herbaceous plant with a long History of traditional medicines uses in many countries especially in tropical and subtropical regions. The present study confirmed the antibacterial potential of aerial parts extracts of E alba in solvents like acetone, ethanol, methanol, aqueous & hexane against selected gram positive & gram-negative bacterial species.

   • Selon Vasuki R (2012)

     Excerpt A comparative analysis in evaluating the hepatoprotective action of ethanolic extract of Eclipta alba (EAE) & Piper longum (PLE) with their combination Biherbal extract (BHE) against carbon tetrachloride (CCl 4) induced hepatic damage is reported in albino rats. The results strongly indicate that BHE has more potent hepato-protective action than EAE or PLE individually against CCl 4 induced hepatic damage in rats.

   • Selon Auteur (1985)

     Excerpt BREVET : 3525363A1-Allemagne-1985: Process for the preparation of extracts of Eclipta alba standardized for wedelolactone and/or desmethyl-wedelolactone and use of the extracts for the preparation of a liver therapeutic : The invention relates to a process for the preparation of extracts of Eclipta alba standardized for wedelolactone and/or desmethy-lwedelolactone, which is characterized by the following stages: (a) extraction of the dried, pulverized above-ground constituents of the plant Eclipta alba with methanol and/or ethanol (b) digestion of the alcohol extract freed from the solvent with water at a temperature of up to 80 DEG C, (c) filtration of the aqueous extract, (d) extraction by shaking of the aqueous extract with an inert organic solvent which is poorly miscible or immiscible with water, (e) performance of a qualitative and quantitative HPLC standardization of the enriched fraction obtained

   • according to (a) to (d) under the following conditions

     Excerpt use of a column packed with reverse phase and acid-containing acetonitrile/water mixtures or methanol/water mixtures as the solvent, & use of the external standard method for the quantitative determination of wedelolactone and/or desmethyl-wedelolactone by means of their peak surface areas. An extract standardized in this way can be used for the preparation of an antihepatotoxic & hepatoprotective medicament.

2. 2

   Diabète mellitus de type II

   Partie usitée : Plante entière.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Ahmad R (2008)

     Extrait Eclipta alba Hassk (Asteraceae) whole plant, roots of Berberis aristata DC (Berbidaceae), stem wood of Betula utilis D. (Myristcaceae) exhibited 7.5, 8.3, 9.2, 6.0, & 8.7% significant fall in blood glucose profile in a single dose experiment on Streptozotocin-induced diabetic rats.

   • Selon Ananthi J (2003)

     Extrait Eclipta alba, an indigenous medicinal plant, has a folk (Siddha & Ayurvedha) reputation in rural southern India as a hypoglycemic agent. In order to confirm this claim, the present study was carried out to evaluate the antihyperglycemic effect of E.A & to study the activities of liver hexokinase & gluconeogenic enzymes such as glucose-6-phosphatase & fructose 1,6-bisphosphatase in the liver of control & alloxan-diabetic rats.

   • Selon Jaiswal N (2012)

     Extrait Antidiabetic effect of Eclipta Alba associated with the inhibition of α-glucosidase & aldose reductase.

   • Selon PHAN TKP (2022)

     Extrait These findings align with the traditional use of EPL for enhancing memory and cognitive function, as well as its potential benefits in diabetes management.

3. 3

   Infection bactérienne : Salmonella typhi, S paratyphi, Shigella sonnei, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis, B Cereus, B megaterium, Staphylococcus aureus, S. pyogenes, K. Pneumoniae, Proteus mirabilis

   Partie usitée : Parties aériennes.

   Références scientifiques (courts extraits)

   Courts extraits uniquement (pas le texte intégral de l’article). Fiches de référence complètes dans l’application Lapo v2.

   • Selon Karthikkumar S (2007)

     Extrait the hexane, ethyl acetate, ethanol & water extract of aerial parts of the Eclipta prostrata were tested for its antibacterial activities against Escherichia coli, Klebsiella pneumoniae, Shigella dysenteriae, Salmonella typhi, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus aureus. Highest activity of both antibacterial & antioxidant was observed only in ethanol & ethyl acetate extracts, while hexane & water extracts did not show any significant results.

   • Selon Uddin N (2010)

     Extrait Large zone of inhibition was observed in disc diffusion Antibacterial screening against gram negative Salmonella typhi, Shigella sonnei, Escherichia coli, Salmonella paratyphi, Pseudomonas sp (1) & Pseudomonas sp (II), & gram-positive Bacillus subtilis, Bacillus Cereus, Bacillus megaterim & Staphylococcus aureus at the concentration of 1mg/disc. this study was subjected to investigate antioxidant, Cytotoxic & antimicrobial (Antibacterial & Antifungal) properties of Eclipta alba ethanol extract. K (2011) — extrait : The present study confirmed the antibacterial potential of aerial parts extracts of E alba in solvents like acetone, ethanol, methanol, aqueous & hexane against selected gram positive & gram-negative bacterial species. Hexane extract of showed E alba high antibacterial activity against S.aureus, B.

   • Selon Selvamani S (2014)

     Extrait Methanol extract of the plant had higher inhibitory action against Staphylococcus aureus, Bacillus subtilis, Proteus mirabilis & Pseudomonas fluorescens. The antibacterial activity of Eclipta alba against three gram positive & five-gram negative bacterial strains were investigated.

   • Selon Rangineni V (2007)

     Extrait Rangineni V et al, Diuretic, hypotensive, & Hypocholesterolemic effects of Eclipta alba in mild Screening of antibacterial & antioxidant activities of leaves of Eclipta prostrata hypertensive subjects: a pilot study.

D’autres indications (y compris d’autres modes d’extraction le cas échéant), posologies, précautions d’emploi et les <strong>références scientifiques complètes</strong> (fiches intégrales, pas seulement les courts extraits ci-dessus) sont disponibles dans la fiche monographique de l’application Lapo v2.